Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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1,000+

Gastroenterologist Jobs in Alabama

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$90K - $110K *

Grow your career with us by leading strategic revenue initiatives, overseeing philanthropic efforts and corporate partnerships, while driving meaningful engagement in intercollegiate athletics and fos...

1 month ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$155K - $197K *

Innovate as a Tech Lead, driving architectural evolution and engineering execution for a global web platform. Collaborate with cross-functional teams to enhance digital experiences through advanced AI...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Join a dynamic team as a strategic partner to senior living operators, driving adoption and ROI. Leverage your clinical expertise and commercial acumen to enhance client relationships and ensure succe...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $300K *

Champion innovative radiology practices to enhance patient care and operational efficiency alongside a dynamic team. Drive clinical excellence and leverage technology to elevate standards across healt...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to managing diverse publications projects from start to finish. Collaborate with multidisciplinary teams, ensure client satisfaction, and maintain project budgets while dr...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$131K - $303K *

Join a team that's at the forefront of healthcare analytics, driving innovation and strategy. You will support financial stewardship, operational excellence, and executive communications in a high-vis...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Unlock potential by partnering with early-stage startups to build robust financial foundations. As a CFO-in-Residence, you'll drive critical finance functions, support fundraising, and shape strategic...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Drive client success by managing relationships, enhancing satisfaction, and identifying growth opportunities. Collaborate with internal teams to deliver exceptional service and exceed client expectati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $160K *

Accelerate growth in telehealth by leading strategic partnerships and business development. Drive revenue through innovative solutions, executive relationships, and a deep understanding of the healthc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Join a dynamic team to drive telehealth sales and strategic partnerships, identifying opportunities and building relationships across the healthcare ecosystem. Own the commercial process from prospect...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive your career with a pivotal role in CMC regulatory affairs, ensuring compliance for biologics and small molecules. Collaborate across teams to prepare high-quality submissions and strategies, imp...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $130K *

Drive rapid service restoration by leading IT incident management processes, ensuring effective communication and coordination for critical incidents. Leverage expertise in troubleshooting and support...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$171K - $231K *

Drive innovative patient recruitment strategies to enhance clinical trial enrollment and retention. Collaborate with cross-functional teams to implement data-driven approaches, optimize patient engage...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Join a team that's redefining forensics and collections globally. Lead a skilled team, enhance operational efficiency, and drive client engagement while ensuring compliance and defensibility across re...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Legal & Accounting

$158K - $326K *

Drive compliance excellence by managing investigations, enhancing policies, and collaborating with cross-functional teams to uphold ethical standards and legal requirements in a dynamic environment...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Accelerate progress at the forefront of healthcare sales by driving revenue growth and expanding strategic partnerships in the RCM sector. Lead comprehensive sales strategies to engage large clients a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$74K - $87K *

Transform customer experiences by leading Unanet ERP implementations, ensuring successful configurations and training for Government Contracting clients. Manage multiple projects, driving adoption and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $110K *

Partner with us to transform healthcare delivery by providing telephonic clinical triage and support. You'll advocate for members, ensuring they receive timely care while collaborating with a dedicate...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$155K - $190K *

Manage the planning and execution of CMC operations across multiple development programs, ensuring alignment with regulatory milestones and efficient collaboration with cross-functional teams and CDMO...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$247K - $309K *

Unlock potential by leading medical strategy for hematologic malignancies. Collaborate cross-functionally to drive evidence generation, stakeholder engagement, and launch readiness, ensuring impactful...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K *

Drive sales success by establishing strong relationships with healthcare professionals, achieving territory goals, and enhancing patient care through innovative medical technologies in a dynamic field...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$100K *

Drive sales success by establishing strong relationships with healthcare professionals, executing territory plans, and enhancing patient care through innovative medical technologies in a dynamic field...

Birmingham, ALRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$108K - $162K *

Lead the charge in delivering exceptional technical support and project leadership for Digital CMU solutions. Collaborate with teams to ensure successful implementations, optimize system performance...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Drive the technical relationship with healthcare accounts, ensuring platform adoption, risk mitigation, and customer growth through proactive advisory and strategic planning. Collaborate with IT teams...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Champion the growth of hematology products by educating healthcare providers, driving demand, and fostering relationships within cancer centers. Leverage cross-functional teams to ensure a positive ex...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.