Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$110K - $130K *

Lead data management initiatives, ensuring quality deliverables and compliance with regulatory standards. Collaborate with vendors and internal teams to enhance processes and drive efficiencies in cli...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$114K - $180K *

Join a team that's driving complex, cross-functional projects to modernize claims processes. As a Project Director, you'll lead initiatives, manage risks, and ensure alignment with organizational goal...

2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Drive your career forward as a Senior Project Manager, leading diverse teams to ensure project success, client satisfaction, and achieving financial goals in a dynamic construction environment...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead the charge in managing multiple large-scale projects, ensuring client satisfaction and adherence to budget and schedule requirements while fostering effective team dynamics and proactive communic...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$95K - $115K *

Champion project success by leading technical teams through complex engineering phases, ensuring on-time, on-budget delivery while fostering collaboration across departments and building strong custom...

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$190K *

Transform the future of public safety as a Director of Product Management, leading a high-performing team to define and deliver innovative SaaS products. Collaborate across departments to drive produc...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Shape the future of architectural design by leading a talented team to deliver innovative new construction projects that meet client expectations and adhere to industry standards, ensuring quality and...

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$124K - $211K *

Drive your career with a Senior Project Manager role overseeing complex manufacturing projects. Collaborate with cross-functional teams to enhance capacity, reduce costs, and ensure operational excell...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $150K *

Lead and manage diverse construction projects, ensuring timely delivery and adherence to budget, quality, and safety standards. Collaborate with stakeholders, mentor junior staff, and drive project su...

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$160K - $180K *

Lead strategic health plan implementations and optimize client solutions. Drive cross-functional collaboration, manage complex projects, and enhance operational workflows to ensure successful launches...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join our Structures team to lead dynamic structural projects in transportation, ensuring innovative solutions and effective project management while mentoring junior engineers and engaging in business...

2 days ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $130K *

Shape the future of transportation infrastructure by leading dynamic structural projects. Leverage your expertise in bridge design and project management to deliver innovative solutions and mentor jun...

2 days ago

  •   8 - 10 years exp.  •   Technical Services

$95K - $115K *

Oversee dynamic structural projects related to transportation, providing expertise in engineering design, project management, and client relations while mentoring junior engineers and ensuring quality...

2 days ago

  •   8 - 10 years exp.  •   Technical Services

$120K - $145K *

Transform the VDC function by leading a multi-region team, enhancing model-based construction strategies, and driving proactive engagement across all project phases to reduce risk and improve executio...

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$115K - $172K *

Transform project execution by leading complex valve initiatives, coordinating with cross-functional teams to ensure timely delivery, manage risks, and enhance profitability while driving customer sat...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$165K - $200K *

Transform federal programs by leading owner's representative services, ensuring effective project delivery from inception to closeout. Leverage commercial real estate expertise to advocate for owners...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Engage in innovative process design engineering for life sciences projects, leading feasibility studies to construction. Collaborate with clients and mentor junior engineers while ensuring compliance...

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$77K - $90K *

Join a team that's integral to global commerce by supporting development and construction projects. This role offers exposure to the full development lifecycle, with opportunities for growth into adva...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$77K - $90K *

Join a team that's integral to global commerce, supporting development and construction projects. This role offers exposure to the full development lifecycle, with opportunities for growth into advanc...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K - $120K *

Drive customer success by managing complex onboarding projects, ensuring alignment across teams, and delivering high-quality implementations. This role is pivotal in creating structured processes in a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$162K - $243K *

Lead a dynamic team in managing complex clinical research trials, ensuring project execution aligns with strategic objectives. Drive process improvements and maintain client relationships while overse...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$162K - $243K *

Lead a dynamic team in managing complex clinical research trials, ensuring strategic execution and client satisfaction. Drive project success through effective communication, budget oversight, and qua...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Join a team that's driving innovation in energy. As a Senior Project Manager, you will oversee complex SLA projects, ensuring smooth execution and transition to operations while coordinating with dive...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$113K - $188K *

Pioneer a transformative Agile project management role overseeing large-scale software development. Lead coordination and execution across multiple teams and workstreams while ensuring alignment with...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Lead the charge in delivering exceptional client service and managing global healthcare market research projects. Utilize your expertise to enhance client relationships, ensure project success, and dr...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.