Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$150K - $214K *

Join a team that's redefining healthcare product management through innovative supply chain solutions. Lead cross-functional initiatives and shape the future of resilience in healthcare with strategic...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$88K - $105K *

Drive your career with a pivotal role in enhancing manufacturing facilities. Lead major projects from concept to completion, collaborating with diverse teams to ensure operational excellence and compl...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$88K - $105K *

Shape the future of manufacturing facilities by leading major construction projects, assessing infrastructure needs, and developing comprehensive improvement plans to enhance operational capabilities...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$112K - $135K *

Join a team that's leading a complex SAP S/4HANA enhancement initiative, overseeing project lifecycles, managing resources, and ensuring alignment with strategic goals while collaborating with diverse...

Today

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Lead complex, cross-functional enterprise programs from strategy to execution, ensuring alignment and measurable business impact. Drive governance, manage risks, and facilitate stakeholder engagement...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$93K - $166K *

Transform the future by leading complex projects that drive innovation and efficiency. Collaborate with cross-functional teams to deliver business value while managing scope, schedule, and resources i...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Join us to lead capital programs, ensuring timely, budget-friendly delivery of high-quality facilities. As a trusted advisor, you'll manage a diverse team and oversee project portfolios from planning...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$88K - $105K *

Lead the charge in managing projects from design to construction, ensuring quality, cost efficiency, and client satisfaction while coordinating teams and resolving complex issues effectively...

Yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$88K - $105K *

Unlock potential by leading project teams to deliver high-quality designs while managing schedules and budgets. Foster client relationships and ensure project success through effective communication a...

Yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Transform product strategy in Chemical & Workplace Safety by leading initiatives from discovery to delivery. Collaborate across teams to balance customer needs and business goals, driving measurable o...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$172K - $203K *

Empower the distribution strategy by designing and managing rate content across channels, ensuring accurate delivery and partner trust. Collaborate with cross-functional teams to build scalable progra...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $120K *

Drive impactful business application initiatives by leading cross-functional projects that enhance efficiency and performance. Collaborate with stakeholders to ensure successful delivery of Microsoft...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$121K - $170K *

Lead the execution of Workplace Office Space Fit-Out projects, ensuring design integration and adherence to standards. Collaborate with clients and teams to manage construction activities, budgets, an...

RemoteRemote

4 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$200K - $240K *

Provide executive-level technical leadership for a WealthTech platform, shaping engineering vision and strategy. Lead high-performing teams, drive platform modernization, and ensure compliance while c...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$130K - $241K *

Contribute to innovative digital product strategies, leveraging AI technologies to enhance customer experiences. Collaborate with cross-functional teams to drive product development from ideation to l...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$130K - $241K *

Join a team that's redefining product management by driving AI-first digital solutions. Collaborate with diverse experts to transform strategic goals into impactful customer experiences, ensuring succ...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Drive complex project implementations by leading cross-functional teams, managing deliverables, and ensuring compliance. Leverage Salesforce expertise to optimize processes and foster client relations...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $135K *

Lead the charge in delivering complex projects from initiation to close, ensuring alignment among stakeholders, effective risk management, and adherence to timelines while utilizing AI tools to enhanc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Join a team that's shaping the future of consulting in P&C insurance. Lead client engagements, ensure quality standards, and foster long-term relationships while driving business growth and mentoring...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Elevate your career by managing complex capital and research projects in Radiation Oncology. Lead diverse teams, ensure compliance, and drive project success from inception to occupancy while meeting...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $191K *

Shape the future of HVAC solutions by leading a dynamic team across Europe, driving product strategy, and influencing innovation through strong stakeholder relationships and market insights...

5 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead and mentor a global team overseeing clinical trial supply operations. Drive compliance and operational excellence across clinical logistics activities, ensuring timely delivery of materials that...

Pennsylvania, USRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Optimize project delivery by leading enterprise SaaS implementations for utility clients. Build strong client relationships, manage competing priorities, and ensure successful project outcomes across...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $130K *

Lead data management initiatives, ensuring quality deliverables and compliance with regulatory standards. Collaborate with vendors and internal teams to enhance processes and drive efficiencies in cli...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$114K - $180K *

Join a team that's driving complex, cross-functional projects to modernize claims processes. As a Project Director, you'll lead initiatives, manage risks, and ensure alignment with organizational goal...

2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.