Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$100K - $120K *

Elevate project outcomes by leading architectural design teams, ensuring compliance with standards, and transforming client visions into high-performing spaces that drive business success...

3 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Transform client visions into high-performing spaces by leading architectural projects, ensuring design integrity, compliance, and quality. Collaborate with teams and clients to deliver innovative sol...

3 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$93K - $159K *

Advance your career by developing and standardizing Procurement processes that enhance compliance and efficiency. Collaborate with cross-functional teams to create clear documentation and governance p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in engineering excellence, overseeing a team of 60 while driving AI initiatives and enhancing operational strategies. Collaborate with product leadership to elevate engineering practic...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $110K *

Drive critical cross-functional initiatives, bridging strategy and execution to enhance mobile and fixed video services. Lead project management, streamline operations, and deliver impactful reporting...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$94K - $132K *

Lead the charge in Post Market Surveillance Analytics, managing a team to enhance complaint handling through innovative data insights, executive reporting, and robust analytics tool governance in a co...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$101K - $152K *

Champion innovative solutions by leveraging Epic expertise to enhance operational efficiency and drive strategic initiatives across healthcare environments, ensuring high-performance standards and cli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $130K *

Champion global expansion initiatives by managing the FedRAMP program. Collaborate with cross-functional teams to ensure project timelines and deliverables are met while navigating a fast-paced enviro...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K *

Unlock potential by leading the strategy and execution of hardware and support services for veterinary practices, driving P&L performance, vendor relationships, and cross-functional collaboration to e...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $190K *

Lead the charge in shaping data platform strategies and governance, driving innovative solutions and team development. Collaborate with partners to enhance AI readiness and ensure successful technical...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$170K - $230K *

Drive strategic growth and innovation in AI-enabled assessment and workforce solutions. Lead high-impact projects, foster collaboration, and enhance AIR's national leadership in education and workforc...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$274K - $457K *

Champion innovative clinical strategies for global drug development, leading cross-functional teams to design and execute pivotal studies, ensuring compliance and regulatory submission excellence for...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Shape the future of project management by leading software implementations, fostering stakeholder relationships, and delivering quality results in complex environments. Collaborate with clients to ens...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$122K - $125K *

Lead and manage warehouse operations to ensure profitability, customer satisfaction, and compliance. Collaborate with teams to enhance service quality and streamline processes while overseeing financi...

3 weeks ago

  •   5 - 7 years exp.  •   Transportation

$130K - $160K *

Lead the charge in project quality management, ensuring compliance with ISO standards and fostering a culture of safety and excellence. Collaborate with diverse teams to drive continuous improvement a...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Energy & Utilities

$135K - $155K *

Drive impactful data solutions by bridging business needs with engineering teams. Own project intake, prioritize requests, and ensure clear communication across departments to enhance efficiency and d...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Drive impactful AI and Agentforce delivery projects, managing customer relationships and internal initiatives. Leverage your strategic planning and analytical skills to oversee project execution and f...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$136K - $160K *

Drive global procurement strategies and foster client relationships while overseeing multi-regional teams. Lead sourcing initiatives, ensure compliance, and deliver measurable value aligned with clien...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$135K - $160K *

Lead the charge in scaling our Customer Success Management team, driving product adoption and retention across diverse customer segments. Collaborate cross-functionally to create impactful processes a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Lead the charge in developing compelling scientific content and strategic initiatives. Collaborate with cross-functional teams to enhance medical communications across therapeutic areas, driving engag...

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's shaping innovative scientific communication strategies. This role combines advanced content development with strategic leadership across therapeutic areas, engaging directly with cl...

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$106K - $132K *

Lead high-impact procurement initiatives, providing strategic guidance and expert consultation to enhance sourcing and supplier management. Drive improvements in procurement practices while influencin...

2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$113K - $141K *

Innovate procurement strategies by leading high-impact initiatives, providing expert guidance, and driving supplier performance. Collaborate across divisions to enhance sourcing practices and ensure a...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$106K - $132K *

Unlock potential by leading high-impact procurement initiatives that drive strategic decisions and enhance supplier performance. Serve as a trusted advisor, guiding cross-functional teams to optimize...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$180K - $270K *

Lead the charge in optimizing HUB operations, ensuring financial performance and safety standards while managing a dynamic team in a fast-paced environment. Drive strategic initiatives and enhance ope...

3 weeks ago

  •   5 - 7 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.