Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$114K - $143K *

Collaborate across teams to define and execute innovative packaging solutions, enhancing product visibility while balancing manufacturing capabilities and regulations. Drive sustainability and efficie...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$88K - $105K *

Drive quality improvement initiatives to ensure compliance with regulatory requirements and enhance market process automation. Collaborate cross-functionally to maintain consistent standards in govern...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $120K *

Lead the transformation of healthcare infrastructure by overseeing EHRM projects, ensuring compliance, quality assurance, and effective management of diverse teams to enhance the VA's capabilities in...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Join a team that's dedicated to enhancing customer success through expert guidance in Privilege Access Management. Leverage your technical skills to support enterprise clients, ensuring seamless deplo...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Transform healthcare delivery by leading program initiatives that drive partner success in value-based care. Utilize data-driven strategies to manage launch processes, ensuring alignment across teams...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$109K - $164K *

Drive advanced digital forensics and incident response initiatives while mentoring a skilled engineering team. Leverage deep technical knowledge to enhance operational capabilities and ensure exceptio...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $150K *

Transform the supply chain landscape by leading procurement and subcontracting efforts, ensuring compliance with federal regulations while driving efficiency and innovation in support of critical defe...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$110K - $130K *

Unlock potential by leading sales strategies in the renewable energy sector. Collaborate with cross-functional teams to engage clients, driving sales growth and building impactful relationships while...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $125K *

Analyze customer needs and drive product initiatives using AI tools. Own features from discovery to delivery, ensuring alignment with business priorities and quality outcomes while collaborating acros...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$74K - $90K *

Coordinate project execution and reporting to ensure success within budget and timelines. Engage in daily activities, manage client relations, and collaborate with internal teams to deliver exceptiona...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$140K - $160K *

Champion innovative media strategies that drive client growth and engagement. Lead cross-channel activation efforts, mentor teams, and collaborate with stakeholders to deliver high-impact campaigns an...

2 weeks ago

  •   8 - 10 years exp.  •   Media

$181K - $216K *

Empower the future of people operations by aligning strategy with business goals. Lead a dynamic team across HR functions, driving engagement, compliance, and organizational design while fostering a c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$175K - $210K *

Drive the development of innovative client reporting solutions, collaborating with cross-functional teams to shape product strategy and influence direction within the Managed Account Solutions platfor...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Empower our Healthcare team by leading project execution, managing resources, and enhancing client relations. Drive improvements, foster teamwork, and ensure compliance with healthcare design standard...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Technical Services

$244K - $305K *

Drive financial strategy and analysis for global commercialization efforts, partnering with cross-functional teams to enhance decision-making and support successful product launches in the biopharmace...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Elevate AI experiences from concept to value by collaborating with engineering and design teams. Drive strategy, build prototypes, and make data-driven decisions to enhance user engagement and product...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Drive the transformation of our accounting function by leading the monthly close, enhancing financial systems, and developing a high-performing team. Leverage AI and automation to improve accuracy and...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Drive the architectural vision by leading project teams, ensuring design excellence, compliance, and client satisfaction while transforming concepts into high-performing spaces that enhance business s...

3 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$95K - $158K *

Lead the charge in coordinating enterprise-wide safety initiatives, ensuring compliance and effective training programs while collaborating across departments to enhance safety management systems and...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $158K *

Drive enterprise-wide safety initiatives by coordinating training, compliance, and data management. Collaborate with cross-functional teams to enhance safety programs and ensure effective implementati...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $140K *

Transform your career by leading product development initiatives that enhance enterprise reporting and analytics. Collaborate with cross-functional teams to deliver high-quality solutions that meet bu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$190K *

Lead our product marketing efforts to drive strategy, market growth, and segmentation for innovative public safety software. Collaborate with teams to translate product features into compelling messag...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K *

Elevate channel strategy and partner relationships to drive revenue growth, enhance market positioning, and ensure effective collaboration across teams, while managing negotiations and performance met...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$220K - $260K *

Elevate the buying experience by leading product strategy, enhancing catalog quality, and optimizing marketplace economics. Drive measurable outcomes through collaboration with operations and engineer...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$126K - $191K *

Lead the charge in implementing an integrated risk framework across the enterprise, enhancing resilience and oversight while guiding teams in risk management, business continuity, and crisis response...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.