Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$195K - $325K *

Elevate the Risk & Compliance strategy for R&D, leading a team to foster a risk-aware culture, manage budgets, and engage with stakeholders to ensure effective cyber risk management across GSK's resea...

Philadelphia, PARemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$96K - $133K *

Join a team that's dedicated to delivering high-quality projects on time and within budget. As a key player, you'll coordinate efforts across departments, ensuring effective communication and resource...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$500K+*

Pioneer the evolution of Netflix's Compute Platform, driving innovation in distributed systems and AI integration. Lead product strategy, enhance efficiency, and collaborate across teams to ensure rob...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$87K - $293K *

Lead cross-functional teams to transform underwriting and claims processes, leveraging advanced analytics and AI solutions to enhance client outcomes and drive business development in the insurance se...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$94K - $293K *

Redefine the future of insurance by leading transformative initiatives that enhance underwriting and claims processes through innovative technology and data-driven strategies, while fostering client r...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$100K - $135K *

Champion a global HSEQ strategy, fostering compliance and quality across operational regions while developing a proactive safety culture and optimizing customer service delivery in the solar and stora...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Deliver innovative solutions by managing complex programs, ensuring seamless execution and coordination across multiple contracts while leveraging extensive IT expertise and leadership skills to drive...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Optimize project outcomes by managing all aspects of land surveying initiatives. Leverage your expertise in GPS and design software to ensure timely execution and client satisfaction while leading a d...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$192K - $310K *

Lead the charge in designing and implementing innovative sales compensation programs that align with business goals. Collaborate with cross-functional teams to ensure compliance, drive performance, an...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$88K - $105K *

Elevate talent management strategies by executing development programs, engaging stakeholders, and driving inclusion initiatives. Contribute to strategic HR priorities while enhancing processes throug...

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$110K - $130K *

Join a team that's redefining product management by building innovative features from concept to launch. Leverage AI tools to enhance efficiency and drive product operations, ensuring seamless deliver...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$154K - $193K *

Shape the future of public sector transformation by leading Organizational Change Management and training initiatives. Collaborate with stakeholders to ensure successful adoption of new systems and pr...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$188K - $230K *

Transform strategic visions into reality by owning product lifecycle from ideation to impact. Collaborate across teams to deliver innovative solutions, drive customer satisfaction, and ensure business...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$242K - $275K *

Lead and elevate the Database Platform team, driving data architecture, reliability, and team culture for scalable data solutions. Collaborate cross-functionally to ensure data integrity and operation...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform business operations by leading a dynamic team, managing financial reporting, and enhancing administrative efficiency across multiple locations. Drive strategic improvements and ensure compli...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$150K - $220K *

Join a dynamic team to define and lead enterprise software delivery strategies, enhancing organizational agility and delivery excellence while aligning technology capabilities with business priorities...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$239K - $298K *

Discover a pivotal role in shaping the future of our engineering function. Lead a small team to enhance our GTM engine, integrating product and marketing efforts while driving innovation in technology...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in complex software implementations for healthcare organizations, overseeing the full lifecycle from initiation to post-launch support while coordinating cross-functional teams and man...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Staffing

$110K - $166K *

Optimize site contract management by reviewing, drafting, and negotiating various legal agreements. Collaborate with clinical teams to ensure timely deliverables and serve as a subject matter expert i...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Transform the payments landscape by leading strategy and execution across product, engineering, and operations. Drive growth and innovation in embedded payments, ensuring alignment and measurable outc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $110K *

Shape the future of HR technology by managing and optimizing our HRIS. Serve as a vital expert, collaborating across departments to enhance system performance, streamline processes, and ensure data in...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Shape the future of mission-critical hardware by leading cross-discipline engineering teams. Drive product development of high-power RF solutions while ensuring compliance, managing risks, and meeting...

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$78K - $95K *

Join a team that's driving project success in commercial environments. Support project management tasks, coordinate resources, and ensure compliance while collaborating with diverse stakeholders to ac...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$135K - $160K *

Elevate our deal desk function by transforming processes into a scalable model. You'll implement AI tools, streamline order forms, and ensure efficient deal structuring while collaborating with cross...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Elevate your career by leading product strategy and innovation in Robotics. Collaborate cross-functionally to define market needs, drive product development, and support global sales efforts while ens...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.