Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.
Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.
Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.
Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.
Water/Wastewater/Water Resources Project Manager
$95K - $115K *
Drive your career with impactful water resources projects, managing teams and client relationships while overseeing planning and design. Leverage your expertise to enhance infrastructure and contribut...
4 weeks ago
Water/Wastewater/Water Resources Project Manager
$90K - $110K *
Explore a pivotal role in managing diverse water resources projects, leading teams, and enhancing client relationships. Drive strategic initiatives for growth in the water/wastewater sector, ensuring...
4 weeks ago
Water/Wastewater/Water Resources Project Manager
$95K - $115K *
Elevate your career by managing diverse water resources projects, leading teams, and fostering client relationships. Drive strategic initiatives for growth while ensuring project success through effec...
4 weeks ago
Water/Wastewater/Water Resources Project Manager
$95K - $115K *
Drive impactful water resources projects by leading teams and managing client relationships. Leverage your engineering expertise to enhance infrastructure and contribute to strategic growth initiative...
4 weeks ago
Water/Wastewater/Water Resources Project Manager
$95K - $115K *
Shape the future of water resources by managing diverse projects, leading teams, and fostering client relationships. Drive strategic initiatives for growth in water/wastewater engineering, ensuring su...
4 weeks ago
Global Product Manager, Analytics Software
$115K - $165K *
Lead the charge in shaping software product strategy and lifecycle for analytics solutions. Collaborate across teams to enhance user experience and drive measurable outcomes, ensuring alignment with c...
3 days ago
$120K - $145K *
Lead the charge in multidisciplinary design delivery for data center projects, ensuring buildable, cost-effective designs from planning through construction. Collaborate with teams to meet tenant need...
1 week ago
Associate Director, Patient Recruitment and Retention Execution Manager
$194K - $266K *
Champion patient engagement strategies by leading a dynamic team focused on optimizing recruitment and retention across clinical trials. Drive performance, enhance collaboration, and ensure successful...
6 days ago
Project Manager - Construction
$80K - $95K *
Empower project success by managing all phases from design to completion, ensuring quality, safety, and customer satisfaction while leading a dynamic team in a fast-paced construction environment...
3 weeks ago
Engineering Manager, Data & Clinical Integration Teams
$125K - $150K *
Lead and develop engineering teams focused on clinical data integration and insights. Drive the direction of data pipelines and ensure impactful, equitable health outcomes through effective collaborat...
Reposted 4 weeks ago
Sr Manager II, EHS Strategic Projects
$110K - $130K *
Unlock potential by leading EHS initiatives across multi-site operations, ensuring safety and compliance through risk assessments, crisis management, and employee health programs. Collaborate with tea...
2 weeks ago
$107K - $145K *
Drive growth by identifying and securing new business opportunities in risk management and medical education. Collaborate with teams to develop proposals, manage sales pipelines, and ensure alignment...
Reposted yesterday
Executive Director, Statistical Programming
$298K - $340K *
Join a dynamic team to lead strategic statistical programming initiatives, ensuring top-quality deliverables and compliance across diverse clinical trials. Collaborate with cross-functional partners t...
Reposted 3 weeks ago
Director, QMS Process Owner - Global Change Control Management
$168K - $228K *
Transform global GxP Change Management processes by leading strategy, governance, and continuous improvement initiatives across the product lifecycle, ensuring effective risk-based changes and collabo...
Yesterday
Vice President, POM Product Management
$150K - $180K *
Lead the charge in developing and executing product strategies that align with client needs and business objectives, driving innovation and collaboration across teams to enhance product offerings and...
2 weeks ago
Senior Director, Business System Strategy & Transformation
$180K - $215K *
Lead the charge in transforming supply chain technology strategies, driving innovation and operational excellence across S2P and O2C value streams. Collaborate with cross-functional teams to enhance d...
Reposted 3 weeks ago
Salesforce Technical Project Manager
$110K - $130K *
Elevate the delivery of Salesforce programs by leading end-to-end project management, ensuring compliance, and fostering collaboration across teams to enhance federal application modernization efforts...
1 week ago
Senior Operational Strategy Director
$203K - $304K *
Champion innovative operational strategies in clinical research, driving excellence in bid defense meetings and proposal development. Collaborate with cross-functional teams to enhance study execution...
2 weeks ago
Director of Business Development
$135K - $150K *
Champion growth by leading strategic business development initiatives, forging partnerships, and driving revenue expansion. Collaborate with executives to align goals and enhance market presence while...
2 days ago
Business Systems & Integration Director
$120K - $145K *
Unlock potential by driving technology initiatives that enhance operations, streamline processes, and improve data utilization across the organization, while leading tuck-in integrations and maximizin...
4 weeks ago
Product Manager - Service of Process
$110K - $120K *
Accelerate product development by leading end-to-end processes, integrating advanced technologies, and driving outcomes across a suite of digital solutions for legal service operations, while ensuring...
Reposted 2 weeks ago
Principal Product Manager, GRC
$150K - $180K *
Drive product strategy and execution for a critical portfolio area, leading cross-functional teams to transform user insights into impactful software solutions while mentoring others and shaping platf...
3 days ago
$98K - $147K *
Lead project scheduling efforts for major capital initiatives, ensuring timely delivery and alignment with client goals. Collaborate with teams to analyze schedules, mitigate risks, and drive project...
2 weeks ago
$80K - $95K *
Shape the future of quality assurance by leading process improvement initiatives and managing a dedicated team to ensure high standards in production and compliance, while fostering a culture of safet...
2 weeks ago
Director, Expert Insights and Delphi Methodology
$100K - $130K *
Champion innovative methodologies in medical communications, leading Delphi studies and expert panels. Drive strategic insights and deliver scientifically rigorous findings to support clinical develop...
3 weeks ago
What types of $100K+ jobs can I find in Pennsylvania?
Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.
Are these Pennsylvania jobs vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.
Can I find remote or hybrid jobs in Pennsylvania?
Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.