Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$110K - $135K *

Contribute to strategic project management within an Investment Office. Lead cross-functional teams, manage project risks, and drive solutions that align with business objectives in the financial serv...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by managing strategic initiatives in investment project management. Collaborate with stakeholders to drive successful project execution, ensuring compliance and operational excelle...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $125K *

Manage a team of medical writers to develop impactful scientific content, ensuring accuracy and compliance. Collaborate with clients and cross-functional teams to drive medical strategies and delivera...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Shape the future of organizational change by developing strategies, managing transitions, and driving transformation initiatives. Collaborate with teams to enhance productivity and ensure successful i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$146K - $215K *

Drive supplier development excellence by leading a team to enhance manufacturing capabilities, operational readiness, and performance improvement strategies, ensuring alignment with business growth in...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the charge in developing and executing innovative marketing strategies for bladder cancer treatments, driving cross-functional collaboration and launch readiness to enhance patient care and provi...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $205K *

Unlock the potential of our Pro offering by leading product strategy and roadmap. Collaborate across teams to enhance customer experiences for short-term rental operators and HOAs, ensuring scalable s...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Hospitality & Recreation

$100K - $150K *

Drive financial strategy by owning planning, forecasting, and analysis. Collaborate with leadership to provide insights that inform decisions, while building robust models in Excel to guide revenue an...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Optimize release orchestration and readiness across interdependent solution areas. Drive sequencing, prioritization, and risk management while ensuring delivery health and readiness criteria are met...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$85K - $100K *

Drive innovative civil engineering designs for land development projects, ensuring compliance with regulations while leading a collaborative team. Manage project lifecycles, mentor junior engineers, a...

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$130K - $165K *

Lead transformative technology projects by managing GIS solutions and systems integration. Mentor a skilled team while ensuring timely delivery and client satisfaction. Collaborate to drive business g...

3 weeks ago

  •   11 - 15 years exp.  •   Technical Services

$125K - $150K *

Lead strategic initiatives to enhance client enablement, manage resources, and drive productivity across the Americas. Collaborate with internal and external partners to achieve organizational goals a...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$170K - $220K *

Lead continuous improvement initiatives across QSR operations, driving cultural transformation and operational excellence. Manage CI strategies, develop leaders, and ensure alignment with enterprise g...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$160K - $175K *

Lead strategic initiatives to enhance customer success for high-value enterprise accounts, fostering long-lasting partnerships, driving engagement, and optimizing retention while managing a high-perfo...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$135K - $202K *

Drive product operations excellence by leading cross-functional teams, enhancing AI integration, and optimizing UX design to ensure a seamless product development lifecycle that empowers rapid, high-q...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Join a dynamic team as a senior leader, driving client relationships and revenue growth in lead-generation sectors. You'll manage a diverse portfolio, ensuring lead quality and speed while leveraging...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $100K *

Unlock potential by building a robust data infrastructure to enhance member experiences and drive growth for diverse businesses. Lead analytics initiatives, develop insights, and support performance m...

Yesterday

  •   5 - 7 years exp.  •   Business Services

$130K - $150K *

Elevate client success by leading a dynamic team to deliver innovative solutions, ensuring seamless execution and strategic alignment with business goals while fostering strong relationships across al...

5 days ago

  •   5 - 7 years exp.  •   Media

$130K - $150K *

Join us to lead client relationships and drive strategic solutions in a dynamic environment. Leverage your expertise to enhance client satisfaction and achieve business objectives while managing a tal...

5 days ago

  •   5 - 7 years exp.  •   Media

$95K - $115K *

Unlock your potential as a Program Manager, leading federal service contracts and driving operational excellence. Collaborate with teams to ensure quality delivery, financial performance, and customer...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$135K - $160K *

Elevate team performance by establishing Scrum practices, coaching self-management, and driving continuous improvement. Facilitate Scrum events, remove impediments, and ensure high-value delivery with...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $150K *

Shape the future of business operations by defining and deploying strategic solutions. Lead cross-functional teams to enhance efficiency, establish success metrics, and foster an inclusive environment...

Pennsylvania, USRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$163K - $261K *

Shape the future of electrification services by leading operations across the West U.S. region, driving performance excellence, and managing nationwide digital automation initiatives while advancing r...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the charge in technical product management, driving strategy and execution for managed accounts integrations. Collaborate across teams to deliver innovative solutions that meet client needs and e...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $160K *

Champion a robust information security program across multiple companies, leading a technical team while engaging in hands-on security operations. Drive risk management, compliance, and governance ini...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.