Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$120K - $145K *

Lead the Validation and Process Engineering teams to ensure compliance and efficiency in pharmaceutical manufacturing. Oversee equipment validation, project management, and cross-department collaborat...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Champion collaborative initiatives by fostering relationships and driving strategic growth. Leverage your expertise to navigate complex operations, optimize performance, and deliver impactful insights...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to managing complex construction projects, ensuring compliance, and fostering collaboration among stakeholders. Leverage your expertise to lead a skilled team and drive su...

3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$88K - $105K *

Lead the management of pharmaceutical programs, ensuring client satisfaction and operational excellence. Oversee daily activities, supervise staff, and drive strategic planning while maintaining stron...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead the charge in managing cross-functional projects with CMOs and suppliers, ensuring compliance and timely execution of manufacturing programs. Collaborate with stakeholders to drive project succes...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$128K - $193K *

Lead the successful delivery of SAP implementation projects, ensuring client satisfaction and project profitability. Manage resources, timelines, and quality assurance while cultivating strong client...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$245K - $392K *

Unlock potential by leading finance transformation initiatives that leverage AI, automation, and advanced analytics. Drive a multi-year roadmap, modernize workflows, and shape a high-performing financ...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Consumer Technology

$105K - $120K *

Transform your career by leading equipment design projects, managing schedules, and ensuring timely delivery while interfacing with clients and teams to drive success and efficiency in engineering ini...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$75K - $90K *

Join a dynamic team to manage commercial roofing projects from start to finish, ensuring timely execution and adherence to specifications while collaborating with various stakeholders to deliver high...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$216K - $318K *

Drive innovation as you lead engineering teams to build and scale Life360's critical platforms. Ensure reliability and security while fostering a culture of accountability and technical excellence for...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Drive construction project success from planning to completion, ensuring timely, budget-conscious delivery while maintaining quality standards and stakeholder satisfaction. Collaborate with teams to i...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$170K - $200K *

Join a team that's redefining financial leadership in a global, multi-site environment. Drive financial reporting, operational finance, and strategic insights while developing talent and ensuring comp...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$111K - $161K *

Transform the future of energy efficiency by leading a $200M facility upgrade project. Oversee construction, engage stakeholders, and ensure compliance with safety standards while managing resources a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$75K - $112K *

Unlock potential by managing complex billing processes and leading a team to ensure accurate invoicing and exceptional customer service. Collaborate across departments to drive efficiency and implemen...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$113K - $188K *

Unlock potential by leading product strategy and management for diverse lines, ensuring customer needs drive innovation while aligning with corporate goals. Collaborate with cross-functional teams to...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform talent management strategies by implementing succession planning and leadership development initiatives. Collaborate with HR and business leaders to enhance workforce planning and execute in...

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$76K - $86K *

Join a team that's dedicated to delivering multiple construction projects on time and within budget. Collaborate with diverse stakeholders while ensuring the university's mission is met through effect...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$118K - $222K *

Empower the delivery of transformative technology initiatives by collaborating with leaders to enhance project execution, manage dependencies, and drive value across teams, ensuring successful outcome...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$118K - $222K *

Unlock potential by leading complex technology initiatives within a strategic transformation program. Collaborate with business and tech leaders to enhance delivery predictability and drive enterprise...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Take ownership of construction projects, ensuring timely completion and budget adherence while collaborating with internal teams and external partners to drive success in a dynamic environment...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Food & Beverages

$184K - $253K *

Empower your career by leading MEP teams on complex projects, mentoring staff, and collaborating with project managers to drive success. Utilize your technical expertise and strategic mindset to enhan...

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$100K - $120K *

Transform your career by managing custom automation projects from design to delivery. Lead cross-functional teams, ensure customer satisfaction, and drive financial results while navigating complex pr...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's driving excellence in federal program management, overseeing multimillion-dollar contracts, and leading diverse teams across multiple locations to ensure compliance and successful o...

1 week ago

  •   11 - 15 years exp.  •   Business Services

$207K - $250K *

Unlock your potential as you lead engineering teams in building innovative platforms and AI experiences. Collaborate across departments to drive technical direction and elevate team performance while...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$145K - $190K *

Lead the charge in designing and optimizing scalable data pipelines using Azure, PySpark, and Airflow. Collaborate with teams to ensure data quality and performance while mentoring engineers and drivi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.