Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.
Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.
Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.
Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.
Project Director - DE Highway Client Service Leader
$125K - $150K *
Unlock potential by managing key client relationships and leading mega projects. Drive financial performance, mentor teams, and collaborate with leadership to achieve business objectives while ensurin...
3 weeks ago
Project Director - DE Highway Client Service Leader
$125K - $150K *
Shape the future of client relations by leading mega projects, developing strategic plans, and ensuring client satisfaction through effective management and collaboration with diverse teams...
3 weeks ago
$90K - $110K *
Join a team that's dedicated to overseeing construction projects, ensuring quality, safety, and budget adherence from pre-planning through execution, while leading and managing diverse teams across mu...
4 weeks ago
Pre-Construction Project Manager
$118K - $148K *
Drive preconstruction excellence for utility-scale renewable energy projects, leading cross-functional teams to ensure alignment on scope, cost, and execution strategies. Influence investment decision...
4 weeks ago
Senior Technical Project Manager - Software Development
$138K - $180K *
Shape the future of medical device development by driving project execution, collaboration, and innovation within a dynamic Research & Development team focused on enhancing healthcare outcomes and pat...
Reposted 5 days ago
Project Manager - Access Service Line
$90K - $105K *
Drive strategic success in large-scale electrical transmission projects by overseeing estimating, pre-construction, and execution phases, ensuring seamless coordination across multiple companies and e...
4 days ago
Manager, Learning & Continuing Education
$80K - $95K *
Develop and manage continuing education programs, ensuring compliance with accreditation standards while driving healthcare innovation and enhancing educational offerings for professionals in the phar...
Reposted yesterday
Director of Product Design, Engage
$195K - $208K *
Reimagine user experiences by leading design for core product features, ensuring seamless integration and customer delight. Collaborate across teams to enhance engagement and trust, shaping the future...
2 weeks ago
$110K - $130K *
Champion enablement initiatives across Technical and Sales domains, partnering with experts to define and execute programs. Lead content development, delivery, and continuous improvement efforts to en...
Reposted 1 week ago
Director, Strategy and Operations
$150K - $180K *
Drive strategic planning and operational excellence for a dynamic Marketing & Communications team. Own budgeting, resource management, and cross-functional partnerships while leading initiatives that...
Today
$120K *
Join a team that's driving impactful cross-functional initiatives by leading strategic delivery efforts. Leverage your project management expertise to align complex projects with enterprise priorities...
2 days ago
Principal Technical Product Manager
$138K - $165K *
Elevate your career by leading complex product initiatives across technical domains. Collaborate with cross-functional teams to drive strategic direction into actionable plans, ensuring measurable out...
1 week ago
Senior Director, Global Study Management
$236K - $354K *
Elevate clinical operations by leading global study management, driving strategic vision, and ensuring high-quality trial execution. Collaborate across teams to optimize resources and foster a culture...
Yesterday
Senior Project Control Analyst
$95K - $115K *
Drive financial governance by tracking budgets, analyzing variances, and generating reports in a federal mission environment. Collaborate with cross-functional teams to ensure compliance and support e...
2 weeks ago
Sr. Manager, Program Management
$120K - $145K *
Manage a diverse portfolio of telemetry systems programs, ensuring strategic execution and customer satisfaction while leading a team of Program Managers to achieve technical and financial objectives...
2 weeks ago
Supervisor, Workday Operations
$80K - $110K *
Champion the operational excellence of Workday by overseeing daily support, configuration, and continuous improvement initiatives. Collaborate cross-functionally to resolve issues and enhance function...
Today
Director, Delivery & Deployment Excellence
$184K - $230K *
Lead the charge in transforming business readiness and deployment excellence across the Americas, ensuring seamless Oracle E-Business Suite upgrades while aligning regional priorities with global stra...
3 days ago
Senior Manager, Clinical Lab Project Management
$134K - $219K *
Lead clinical laboratory operations for precision medicine projects, ensuring timely deliverables and risk management across therapeutic areas. Collaborate with cross-functional teams to support clini...
3 weeks ago
$145K - $220K *
Drive the development and commercialization of innovative digital solutions for federal clients. Lead cross-functional teams, engage with customers, and manage the full product lifecycle from concept...
2 days ago
$90K - $110K *
Join a team that's dedicated to driving excellence in manufacturing processes. Oversee daily production operations, ensuring quality, safety, and efficiency while fostering a culture of continuous imp...
Reposted 3 days ago
Project Manager (Guidewire) - REMOTE
$120K - $145K *
Lead the charge in transforming core insurance technology platforms, overseeing a large team while ensuring operational excellence and driving modernization from legacy systems to Guidewire solutions...
2 weeks ago
Senior Director, Facilities, Real Estate & Security Operations
$159K - $215K *
Join a team that's driving operational excellence across 25+ sites, overseeing facilities, real estate, and security operations to ensure safe, efficient environments that support high-quality care de...
Today
Executive Director, PDMB Outsourcing
$255K - $402K *
Lead and innovate within the Outsourcing team, driving strategic partnerships and operational excellence in drug metabolism and bioanalytical development, while managing a diverse team to enhance scie...
2 weeks ago
Associate Director, Strategy & Operations
$179K - $248K *
Lead the charge in operationalizing strategy and driving cross-division initiatives. Collaborate with senior stakeholders to enhance efficiency and client satisfaction in a fast-paced corporate travel...
3 weeks ago
Director of Project Management
$120K - $145K *
Lead the charge in establishing a robust Project Management Office to drive enterprise initiatives across multiple facilities, ensuring projects are delivered on time and within budget while fostering...
1 week ago
What types of $100K+ jobs can I find in Pennsylvania?
Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.
Are these Pennsylvania jobs vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.
Can I find remote or hybrid jobs in Pennsylvania?
Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.