Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$126K - $162K *
Drive project success by leading design and construction phases, managing teams, and ensuring client satisfaction in commercial and mission-critical environments. Collaborate with stakeholders to deli...
3 weeks ago
Project Manager, Business Improvement
$100K - $120K *
Empower your career by driving impactful business improvement initiatives. Collaborate with cross-functional teams to manage projects, analyze data, and enhance operational efficiency in a dynamic env...
Reposted today
$100K - $140K *
Empower global business practices by leading diverse project teams in innovative industries. Collaborate with stakeholders to ensure project success through effective management and integration of cut...
Reposted 2 weeks ago
$140K - $150K *
Unlock potential by leading software implementation projects, applying Agile methodologies, and ensuring client satisfaction through effective communication and collaboration with cross-functional tea...
2 days ago
$109K - $129K *
Take ownership of product development in a dynamic, cross-functional team. Drive AI-assisted innovation from problem framing to launch, focusing on customer outcomes and strategic impact in a hyper-ag...
1 week ago
Director of Engineering, Product
$250K - $290K *
Elevate your career by leading a high-performing engineering team, driving strategy and innovation in web3 technologies. Shape the future of decentralized systems while ensuring top-tier security and...
Reposted 4 days ago
$125K - $150K *
Manage client relationships by leading strategic planning and execution of wealth strategies. Collaborate with families and their advisors to ensure alignment with their goals while guiding a dedicate...
1 month ago
Senior Technical Project Manager (Enterprise Modernization & AI Delivery
$130K - $155K *
Lead cross-functional teams to drive enterprise modernization through AI solutions. Oversee complex implementations, ensuring alignment across technical and business stakeholders while delivering meas...
1 week ago
$110K - $130K *
Shape the future of project management by leading complex initiatives, ensuring timely delivery and budget adherence while leveraging your expertise in Material Handling Systems and team leadership to...
Today
$110K - $130K *
Accelerate progress at managing complex projects with $30M+ budgets, ensuring timely delivery and stakeholder satisfaction. Leverage your expertise in project governance and material handling systems...
Today
$108K - $155K *
Elevate your career by leading complex public sector deployments, ensuring seamless execution of Zero Trust solutions while collaborating with cross-functional teams to achieve impactful business outc...
2 days ago
Sr Director, Product Management
$160K - $200K *
Drive the evolution of dealer marketing solutions by leading product management efforts, overseeing current offerings, and defining a next-gen platform that enhances customer engagement and retention...
1 week ago
Senior Project Manager - Life Sciences
$110K - $130K *
Pioneer innovative solutions in construction management, leading complex design-build projects in the Life Sciences sector. Drive project success from inception to closeout while mentoring a dynamic t...
2 weeks ago
Senior Project Manager - Transportation Design
$134K - $241K *
Deliver transformative transportation solutions by leading project teams, enhancing community infrastructure, and ensuring excellence in project execution through strategic planning and collaboration...
Reposted 4 days ago
Senior Director, Business Management & Execution Lead
$170K - $200K *
Champion operational excellence by leading business unit strategies, enhancing performance management, and driving cross-functional collaboration to achieve enterprise goals and scalable solutions...
4 days ago
$80K - $95K *
Lead a dynamic team to drive project success, ensuring optimal performance and efficiency while managing timelines, resources, and stakeholder communication throughout the project lifecycle...
2 weeks ago
Program Manager of Technical Development
$140K - $185K *
Drive technical excellence by developing standards and processes for commissioning, ensuring consistent execution across projects. Collaborate with cross-functional teams to enhance workforce capabili...
2 weeks ago
$140K - $150K *
Join a team that's driving strategic project execution and mentoring talent. Leverage advanced data analytics to build impactful dashboards and navigate stakeholder relationships, ensuring alignment w...
1 month ago
$89K - $150K *
Transform sourcing strategies to optimize cost, quality, and risk while managing competitive events and stakeholder partnerships. Drive process improvements and digital transformation in sourcing and...
2 days ago
$80K - $95K *
Support the execution of technical projects, ensuring alignment with scope, schedule, and budget. Collaborate with cross-functional teams to deliver successful outcomes for food retail customers while...
Reposted 2 days ago
Program Manager, Enterprise Growth & Capital Programs
$100K - $180K *
Lead the charge in delivering enterprise-level growth programs by ensuring alignment across all functions, driving planning and execution adherence, and managing complex initiatives for timely product...
Reposted 3 weeks ago
Program Manager, RES (Risk Engineering Solutions)
$105K - $125K *
Join a team that's driving innovation in risk engineering solutions. This role focuses on managing complex programs across global teams, enhancing workflows, and ensuring effective collaboration to me...
Today
Product Manager, Discovery & Use-Case Portfolio
$110K - $130K *
Lead the charge in defining and prioritizing AI use cases, ensuring alignment with engineering capabilities. Shape a new portfolio by actively discovering opportunities and writing clear requirements...
Reposted today
Director, Technical Program Management, Ad Tech
$162K - $228K *
Transform the Ad Tech landscape by leading cross-functional teams to ensure seamless delivery and execution of complex technology portfolios, driving strategic initiatives and fostering collaboration...
2 weeks ago
Director, Product Management - Enterprise Data Platform
$107K - $150K *
Shape the future of our enterprise data platform by leading product strategy, defining capabilities, and ensuring alignment across business and technology teams to deliver scalable, secure, and truste...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.