Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Manager, Deployed Engineering
$150K - $180K *
Pioneer innovative solutions as a Senior Manager in Deployed Engineering, leading hands-on deployments and building a high-performing team. Collaborate closely with customers and internal teams to dri...
3 weeks ago
Senior Manager, Strategic Growth
$110K - $130K *
Lead the charge in expanding into new healthcare verticals by developing and executing go-to-market strategies, managing partnerships, and driving campaign performance. Collaborate with cross-function...
3 weeks ago
$115K - $207K *
Elevate business growth by driving new client acquisitions and expanding existing accounts, while monitoring customer satisfaction and providing operational guidance across multiple plants to ensure s...
Reposted 1 week ago
$80K - $125K *
Unlock potential by guiding clients through Salesforce implementations, enhancing communication, managing change impacts, and delivering effective training to end-users, ensuring a smooth transition a...
Today
$82K - $153K *
Unlock potential by driving acquisition strategies and building relationships with agency owners. Collaborate with leadership to enhance deal pipelines and support growth initiatives through effective...
1 week ago
$125K - $295K *
Drive global delivery success by managing hub economics, resourcing, and operational systems. Collaborate with finance and commercial teams to ensure consistent pricing and routing, while overseeing d...
3 weeks ago
$170K - $200K *
Shape the future of healthcare integrations by leading product strategy and execution for seamless data connectivity between customer systems and our platform, enhancing user experience and operationa...
Today
Systems Engineer, Manager - Operations
$121K - $164K *
Champion a team of analysts to enhance enterprise infrastructure services, ensuring reliable support and operational excellence. Collaborate with cross-functional teams to align priorities and drive c...
2 weeks ago
Digital Delivery Manager - Energy Advisory | 1898 & Co
$110K - $130K *
Advance your career by leading digital delivery and innovation in Energy Advisory. Collaborate across teams to connect business needs with digital solutions, ensuring scalable and sustainable project...
2 weeks ago
Sr. Manager, Sales Strategy and Operations - Omni + OBT
$142K - $197K *
Drive strategic improvements and operational efficiency in Partnerships by establishing frameworks, integrating AI solutions, and optimizing team performance, all while collaborating with cross-functi...
Reposted 3 weeks ago
$95K - $115K *
Lead the proposal lifecycle by collaborating with cross-functional teams to create compelling, compliant proposals that drive growth in government contracting. Utilize your expertise to enhance proces...
4 days ago
$110K - $130K *
Reimagine space management and GIS solutions, driving innovation in product strategy and execution. Collaborate with universities to enhance workflows, optimize features, and deliver impactful results...
Yesterday
Project Manager - Building Structural Engineer 10+ Years
$110K - $155K *
Join a dynamic team as a project manager focused on structural engineering, overseeing diverse building projects from expansions to renovations. Mentor junior staff while ensuring quality and accuracy...
3 weeks ago
$122K - $261K *
Elevate employee experiences by leading digital transformation initiatives, providing strategic guidance, and implementing scalable solutions across enterprise environments to enhance productivity and...
2 weeks ago
Manager, Data Protection Analysts (Americas)
$120K - $145K *
Shape the future of data protection by leading a high-performing team of analysts. Drive incident response, enhance security strategies, and collaborate with clients to mitigate risks in a fast-paced...
1 week ago
$94K - $168K *
Drive strategic resource management by aligning talent with project needs, optimizing workforce planning, and enhancing operational efficiency across key business units to support organizational succe...
Today
Staff Software Engineer, Java Backend
$120K - $170K *
Lead engineering efforts by writing production code and mentoring a team. Drive modernization initiatives through Java microservices while managing performance and growth of engineers. Collaborate wit...
Reposted 3 days ago
$154K - $260K *
Champion cutting-edge AI solutions by leading a team to deploy real-time edge models, enhancing safety across millions of devices. Drive technical strategy and foster collaboration to deliver impactfu...
Today
$125K - $145K *
Drive product strategy and modernization for merchant onboarding solutions, collaborating with cross-functional teams to enhance risk management capabilities and ensure market-leading standards in a d...
Reposted 2 weeks ago
Principal Technical Program Manager
$125K - $150K *
Lead high-impact, cross-functional technical programs, translating business vision into structured execution. Drive Agile practices, enhance team efficiency, and ensure alignment with company objectiv...
1 week ago
Director, Business Development
$125K - $180K *
Elevate your career by driving business growth in the biotech and pharma sectors. This role allows you to influence strategies, build partnerships, and deliver sustainable revenue through innovative p...
Reposted yesterday
Senior Product Manager, Device Experience
$130K - $219K *
Drive the vision for Samsara device installations, enhancing user experiences and ensuring rapid, accurate setups. Collaborate with cross-functional teams to optimize the install process, making impac...
Reposted 3 weeks ago
Director, Onboard Core Software
$240K - $330K *
Champion the development of onboard software for autonomous vehicles, leading cross-functional teams to ensure a robust software foundation. Drive strategic vision, quality, and operational excellence...
3 weeks ago
$125K - $190K *
Accelerate progress at a leading Customer Success team, driving renewal outcomes and enhancing team effectiveness through innovative engagement strategies and AI-driven solutions for a diverse portfol...
2 weeks ago
Corporate Finance Manager, Fundraising and Investor Relations
$133K - $166K *
Champion the fundraising efforts of a dynamic corporate finance team, managing complex debt and equity processes while collaborating with senior leadership to craft compelling narratives for investors...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.