Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$92K - $98K *
Take ownership of federal proposal efforts, coordinating cross-functional teams to develop compliant, compelling proposals that align with strategic growth objectives and enhance organizational effect...
2 weeks ago
IT Senior Manager - Portfolio Management Office (PMO)
$120K - $145K *
Lead the charge in transforming portfolio management practices, enhancing strategic alignment, and fostering high-performing teams. Collaborate with executives to drive technology investments that del...
2 weeks ago
Director, Business Transitions
$225K - $250K *
Engage with business owners navigating M&A transactions, providing integrated planning and support. Collaborate with deal teams to ensure seamless transitions and optimize after-tax outcomes during cr...
1 week ago
Director, Proactive Defense Operations
$168K - $281K *
Lead the charge in Proactive Defense Operations, transforming threat data into automated defenses. Drive strategy, team performance, and operational excellence while collaborating across functions to...
1 week ago
Senior Manager, Sales Operations
$115K - $120K *
Lead the charge in driving operational excellence and strategic enablement across global Inside Sales teams, enhancing commercial effectiveness and delivering exceptional client value through innovati...
3 weeks ago
$120K - $145K *
Empower the development of innovative banking solutions by driving product strategy, collaborating across teams, and delivering scalable capabilities that enhance customer experiences and meet busines...
Reposted today
Director, Digital Systems & Strategic Growth
$140K - $180K *
Transform the digital manufacturing landscape by driving sales growth and market expansion. Collaborate across teams to develop strategies, support federal opportunities, and enhance customer value th...
3 weeks ago
Director, Client Media Solutions
$100K - $140K *
Drive innovative media strategies for healthcare clients, leveraging audience insights and performance data. Collaborate with cross-functional teams to enhance planning processes and deliver impactful...
2 weeks ago
Director, Professional Services (Ellucian Colleague and Anthology)
$125K - $150K *
Unlock potential by leading client engagements in higher education, ensuring delivery excellence and fostering executive relationships. Drive project success through oversight, escalation management...
Yesterday
Senior IT Project Manager (NSGS)
$140K - $180K *
Lead the execution of complex IT infrastructure projects, ensuring mission success for critical U.S. Coast Guard programs. Collaborate with stakeholders and manage resources to deliver seamless techno...
1 week ago
$85K - $124K *
Drive impactful SAP projects as a Project Manager/Scrum Master, leading teams to deliver innovative solutions. Collaborate with stakeholders, manage product backlogs, and ensure agile practices to mee...
1 week ago
Senior Manager, Program Management Operations
$143K - $179K *
Lead cross-functional initiatives, optimizing governance and operational readiness for programs. Collaborate with stakeholders to enhance portfolio execution, reporting, and PMO capabilities, driving...
Reposted 1 week ago
$150K - $180K *
Drive mobile engineering excellence across diverse product teams, ensuring strategic direction, fostering collaboration, and enhancing delivery. Lead managers, shape architecture, and cultivate a prod...
3 weeks ago
Senior Engineering Project Manager - Connectivity
$120K - $140K *
Transform your career by leading complex design change projects from inception to execution. Collaborate with cross-functional teams, manage substantial budgets, and drive innovation in a fast-paced e...
2 weeks ago
Program Director, Adobe Implementation
$75K - $150K *
Transform client initiatives by leading complex projects from planning to execution. Collaborate with teams and stakeholders to ensure timely, on-budget delivery while maintaining high standards of qu...
Yesterday
Project Manager (Civil Construction)
$85K - $102K *
Drive project success by leading teams, managing schedules, and ensuring quality outcomes in civil energy projects. Collaborate with stakeholders to align on goals and navigate complexities throughout...
1 week ago
Project Manager (Civil Construction)
$80K - $95K *
Elevate your career by leading project teams to deliver quality civil infrastructure solutions. Drive project success through strategic planning, risk management, and effective communication with stak...
3 weeks ago
Project Manager for Service Delivery - Atlanta, GA
$95K - $115K *
Join a team that's dedicated to delivering successful projects on time and on budget. As a key player, you'll drive project planning, coordinate with stakeholders, and ensure effective communication t...
Reposted 3 weeks ago
Workday Adaptive Planning Senior Manager
$178K - $338K *
Redefine financial planning with leadership in Workday Adaptive Planning implementations. Collaborate across teams to enhance reporting, optimize processes, and drive enterprise performance management...
Reposted 4 days ago
Interior Design Project Manager - Corporate
$80K - $95K *
Transform project execution by leading design and construction initiatives. Manage budgets, timelines, and client expectations while fostering collaboration and ensuring project excellence from start...
1 week ago
$88K - $105K *
Empower successful project delivery by managing engineering solutions that exceed client expectations. Collaborate with cross-functional teams to oversee project budgeting and scheduling while ensurin...
Reposted 1 week ago
Associate Director, Project Management
$120K - $140K *
Advance your career by leading project delivery and operational excellence in a dynamic healthcare agency. Collaborate across teams, manage client relationships, and drive innovative solutions to enha...
Today
Finance Manager, Adaptive Planning
$110K - $130K *
Lead the charge in optimizing our Adaptive Planning platform, ensuring accurate data management and seamless integrations. Collaborate with cross-functional teams to enhance reporting and streamline f...
3 days ago
Project Manager, Evidence Synthesis
$68K - $103K *
Engage with a dynamic team to drive successful execution of HEOR projects, ensuring timely delivery and high-quality outcomes through strategic portfolio management and collaboration with cross-functi...
Reposted 1 week ago
Deputy PM - Construction Manager, Senior
$125K - $225K *
Oversee complex industrial construction projects, ensuring safety, quality, and timely completion. Lead multidisciplinary teams, manage contractor performance, and coordinate with stakeholders to achi...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.