Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Director, Project Management Jobs in Mississippi

Sort By: Relevance

$120K - $193K *

Join us in transforming infrastructure delivery by leading product strategy and execution for Infrastructure as Code. Collaborate across teams to enhance automation, improve user experiences, and driv...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Shape the future of battery storage procurement by leading strategic sourcing, negotiating contracts, and driving supplier performance to ensure cost competitiveness and supply security in a dynamic g...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $235K *

Transform data access and orchestration by managing a self-service platform that empowers engineers and analysts, ensuring safe, efficient workflows while driving innovation in AI integration and syst...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$134K - $219K *

Unlock potential by leading global site start-up strategies for complex clinical trials. Drive operational excellence, ensure compliance, and collaborate with cross-functional teams to accelerate stud...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$131K - $155K *

Drive regional website strategy for multiple international markets. Collaborate cross-functionally to enhance user experience, support AEO/SEO initiatives, and manage web performance metrics. Lead exp...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Champion the development of AI-driven products, leading strategic initiatives and execution. Drive product roadmaps, manage budgets, and ensure alignment with business goals while delivering impactful...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's redefining product management by leading AI and automation initiatives. Drive strategic roadmaps, enhance operational efficiency, and deliver impactful solutions while collaborating...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$133K - $210K *

Transform internal communications by connecting employees to strategy and culture. Lead a team, advise executives, and drive effective communication strategies that enhance organizational alignment an...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$100K - $120K *

Drive growth by leading a high-performing sales team focused on early-stage companies. Collaborate with leadership to refine strategies, enhance sales processes, and foster a supportive culture, ensur...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$145K - $218K *

Architect innovative market access strategies to enhance U.S. reimbursement for cutting-edge healthcare solutions. Collaborate across functions to drive payer engagement, coding, and coverage initiati...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$175K - $185K *

Unlock potential by leading global product strategies that drive growth and innovation. Collaborate cross-functionally to prioritize customer needs, enhance product performance, and support internatio...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$108K - $144K *

Champion maintenance planning by overseeing work order processes, coordinating outages, and ensuring compliance with policies. Collaborate with teams to optimize planning, reduce inventory, and enhanc...

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$140K - $165K *

Lead the charge in cultivating high-impact B2B client relationships through strategic oversight, innovative marketing solutions, and dedicated account management while driving growth and profitability...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Shape the future of clinical trials by managing CST services, ensuring data quality and integrity. Collaborate with teams and vendors to deliver projects from start to finish, while mentoring others a...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $190K *

Empower our sales team by driving strategic growth in key accounts. Leverage your expertise in Enterprise SaaS to navigate complex sales in the Life Sciences sector, fostering partnerships and deliver...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$194K - $228K *

Lead the charge in sustainability as a senior executive, driving growth and innovation in occupier facilities management. Mentor teams, enhance client relationships, and spearhead strategic initiative...

United StatesRemote

Reposted 5 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$160K - $200K *

Lead the charge in strategic pre-award contracting, driving compliance and operational excellence. Oversee a high-performing team while collaborating across functions to enhance efficiency and support...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Join a dynamic team as a finance leader, driving strategic growth through financial planning, investment analysis, and operational excellence. Collaborate with executives to shape business performance...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$119K - $186K *

Transform the future of supply chain technology by leading innovation initiatives, managing a structured evaluation process, and engaging stakeholders to drive measurable value and strategic alignment...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $200K *

Elevate healthcare technology by owning mobile and web apps that enhance clinician workflows. Drive product direction, prioritize initiatives, and ensure patient safety while leveraging AI to improve...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$240K - $330K *

Transform security operations by leading a dynamic Product Security team. Drive risk-based strategies, empower engineering teams, and enhance security posture through automation and collaboration. Sha...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Transform data into actionable insights by building robust data pipelines, dashboards, and monitoring frameworks. Leverage expertise in Skyline DataMiner to enhance network performance analytics and e...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Staffing

$110K - $138K *

Unlock potential by leading preconstruction for high-voltage electrical projects. Manage planning, estimating, and client coordination to ensure successful execution from concept to construction hando...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$135K - $160K *

Unlock your leadership potential by guiding product engineers in creating exceptional developer experiences. This role blends technical expertise and product vision, enabling you to drive impactful in...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Shape multi-year commodity strategies for electrical equipment, ensuring robust supplier negotiations and capacity management. Collaborate with engineering to optimize designs and mitigate risks throu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.