Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Director, Project Management Jobs in Mississippi

Sort By: Relevance

$96K - $128K *

Unlock potential by managing procurement processes, ensuring vendor compliance, and facilitating bid preparations. Collaborate with project teams to optimize purchasing strategies and maintain operati...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$95K - $123K *

Lead the charge in pharmaceutical meetings operations, driving client partnerships and operational excellence while navigating compliance. Shape processes and enhance stakeholder engagement to deliver...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Transportation

$125K - $150K *

Drive high-value B2B paid media strategies and growth across multiple channels while leading a team of media professionals, ensuring client success and operational excellence in performance marketing...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Elevate project management effectiveness by providing advanced administrative support, ensuring adherence to policies, and enhancing team performance through training and reporting. Drive project succ...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$180K - $230K *

Join a dynamic team as you lead engineering efforts to develop an AI Patient Engagement Agent, transforming clinical trials by automating patient interactions and enhancing operational efficiency for...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $230K *

Lead the charge in optimizing manufacturing processes through effective management of the Automation and Controls team, ensuring strategic alignment with innovation initiatives while fostering a cultu...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $190K *

Drive member activation by leading a cross-functional team to optimize outreach, incentives, and messaging strategies. Own the activation roadmap and funnel metrics to enhance engagement and ensure sc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$212K - $318K *

Shape the future of patient-centered outcomes in oncology by leading global strategies for clinical assessments and patient experience data, ensuring impactful evidence generation and regulatory succe...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$275K - $350K *

Lead the charge in building a subscription research business, driving sales and market strategy across energy, trading, and institutional sectors. Collaborate with analysts to tailor offerings and est...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Lead transformative facilities initiatives by analyzing data, optimizing performance, and managing capital projects. Collaborate across teams to drive efficiency, reduce costs, and enhance restaurant...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$160K - $200K *

Shape the future of our web strategy by leading a cross-functional team to optimize user experience, drive demand generation, and enhance web performance. Your expertise will transform our website int...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $160K *

Elevate digital experiences by guiding site operations and enhancing user engagement. Collaborate with cross-functional teams to implement innovative features and optimize performance metrics, driving...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Empower a team by leading GIS and Real Property projects, enhancing data quality and usability for Army installations. Collaborate with stakeholders to deliver innovative geospatial solutions and ensu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$107K - $199K *

Lead transformative process improvements to enhance healthcare quality and efficiency. Collaborate with teams to elevate performance metrics, oversee cultural competency initiatives, and drive strateg...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Optimize quality operations for large-scale data pipelines, ensuring high standards and consistency across diverse datasets. Lead a team to enhance efficiency and reliability in audio data processing...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Drive software engineering initiatives by leading teams to deliver innovative digital solutions. Define technology strategy, oversee development processes, and foster a culture of excellence and colla...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$80K - $90K *

Join a team that's transforming customer onboarding by leading complex implementations, aligning stakeholders, and delivering scalable solutions that drive success and revenue. Your expertise will bri...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$236K - $296K *

Lead innovative product initiatives by owning vision, strategy, and execution. Collaborate with cross-functional teams to transform ideas into scalable solutions, driving impactful outcomes for the co...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $170K *

Join a team that's expanding strategic partnerships with consulting firms to enhance supply chain solutions. Drive growth through collaboration, relationship management, and innovative go-to-market st...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$130K - $180K *

Join a team that's redefining data products on a modern platform. As a Senior Technical Product Manager, you'll drive the strategy for our data platform and API, ensuring quality, governance, and a se...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Staffing

$125K - $150K *

Drive the evolution of a next-gen Privileged Access Management platform, collaborating across teams to create user-centric and secure solutions while ensuring technical excellence and scalability in a...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$201K - $251K *

Shape the future of revenue accounting by leading critical processes and driving scalable methodologies to support commercial growth. Collaborate with cross-functional teams to deliver actionable fina...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $155K *

Unlock potential by leading strategic partnerships in Creative Software Licensing. Drive growth through innovative deals, build relationships with developers, and shape the future of digital tools for...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$95K - $115K *

Lead and enhance day-to-day accounting operations, focusing on accounts payable, receivable, and cash management. Collaborate with cross-functional teams to ensure accurate, timely transactions while...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $165K *

Elevate your career as a Scientific Product Owner, driving innovation in clinical genomics software. Collaborate with cross-functional teams to translate scientific needs into actionable requirements...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.