Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$142K - $197K *

Drive strategic improvements and operational efficiency in Partnerships by establishing frameworks, integrating AI solutions, and optimizing team performance, all while collaborating with cross-functi...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$254K - $317K *

Lead innovative marketing strategies and enhance brand presence while overseeing comprehensive communications efforts. Drive engagement with stakeholders and ensure operational excellence within the C...

3 days ago

  •   11 - 15 years exp.  •   Legal & Accounting

$166K - $249K *

Shape the future of AI in healthcare by defining and executing a strategic roadmap that integrates intelligent solutions into clinical workflows, ensuring safety and efficiency while collaborating wit...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$132K - $278K *

Optimize enterprise-wide digital employee experiences by leading initiatives that enhance productivity and operational efficiency through strategic technology solutions and architecture guidance...

2 days ago

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Advance the future of orthodontics by leading complex product programs, ensuring seamless integration across technical domains while coordinating cross-functional teams to achieve strategic business o...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$132K - $278K *

Transform enterprise environments by leading digital employee experience initiatives, providing strategic guidance, and enhancing productivity through innovative workplace technologies and solutions...

2 days ago

  •   8 - 10 years exp.  •   Business Services

$130K - $160K *

Lead engineering efforts by writing production code and mentoring a team. Drive modernization initiatives through Java microservices while managing performance and growth of engineers. Collaborate wit...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$140K - $180K *

Manage complex, custom-engineered projects from order to acceptance, ensuring alignment between customer expectations and internal teams. Drive project success through leadership, problem-solving, and...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$130K - $150K *

Elevate laboratory operations by managing logistics, compliance, and safety in a dynamic research environment. Collaborate with scientists to streamline processes and ensure a well-functioning lab tha...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive product strategy and modernization for merchant onboarding solutions, collaborating with cross-functional teams to enhance risk management capabilities and ensure market-leading standards in a d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by managing comprehensive data solutions for defense programs, ensuring effective documentation, compliance, and collaboration across teams to support the modernization and sustainmen...

5 days ago

  •   11 - 15 years exp.  •   Information Technology

$84K *

Join a team that's dedicated to supporting mental health consumers in transitioning from hospital to community living. Oversee clinical operations, enhance team collaboration, and foster a compassiona...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $210K *

Transform the Platform organization by owning roadmap planning, development processes, and cross-functional coordination. Drive execution and ensure alignment with business goals while providing leade...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$148K - $165K *

Drive the engineering team behind high-assurance cryptographic products, managing development from design to delivery. Collaborate with program managers to ensure security, quality, and performance st...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $95K *

Drive impactful administrative support across the Faculty of Arts and Sciences, overseeing a team to enhance event management and financial services while ensuring seamless operations and client satis...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Lead cross-functional efforts to drive execution in a fast-paced remote environment, overseeing key product initiatives and customer issues in our Privileged Access Management portfolio, while ensurin...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$108K - $130K *

Lead the charge in optimizing IT operations and security across multiple business units. Oversee service management, endpoint security, and compliance, ensuring seamless integration and support for a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Advance organizational growth by leading financial strategy, planning, and analytics. Collaborate with executive leaders to translate data into insights, enhance business performance, and drive inform...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $219K *

Drive the vision for Samsara device installations, enhancing user experiences and ensuring rapid, accurate setups. Collaborate with cross-functional teams to optimize the install process, making impac...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$117K - $156K *

Join a team that's driving strategic portfolio planning in R&D, enabling effective decision-making across drug discovery and development. Collaborate with cross-functional teams to ensure accurate, re...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $156K *

Elevate strategic decision-making by managing integrated program plans, ensuring accurate portfolio data, and collaborating with cross-functional teams to drive continuous improvement in a fast-paced...

Cambridge, MARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $156K *

Optimize strategic portfolio planning by developing integrated program timelines and collaborating with cross-functional teams to drive data accuracy and informed decision-making in R&D...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $150K *

Transform the energy efficiency landscape as a Senior Program Manager, leading utility programs in New England. Drive strategy, financial performance, and client relationships while managing cross-fun...

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$240K - $330K *

Champion the future of onboard software for autonomous vehicles, leading teams to deliver robust embedded firmware, operating systems, and middleware. Drive strategic vision and ensure quality across...

1 week ago

  •   11 - 15 years exp.  •   Transportation

$240K - $330K *

Champion the development of onboard software for autonomous vehicles, leading cross-functional teams to ensure a robust software foundation. Drive strategic vision, quality, and operational excellence...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.