Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$140K - $170K *

Join a dynamic team to optimize operational systems, drive growth, and enhance performance across departments. Collaborate with leadership to ensure strategic goals translate into measurable results a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$82K - $111K *

Lead the charge in managing multiple retail construction projects, ensuring timely and budget-compliant store openings. Collaborate with internal and external partners to drive successful project exec...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$82K - $111K *

Grow your career with a dynamic team managing retail construction projects. Oversee store development, coordinate with internal and external partners, and ensure timely, budget-friendly project comple...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Pioneer operational excellence as you support the East Coast region, driving initiatives, managing projects, and providing strategic insights to enhance leadership effectiveness and regional performan...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Accelerate progress at the forefront of AI factory design delivery, leading multidisciplinary teams to ensure successful project execution from concept to handover while balancing quality, cost, and o...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$187K - $230K *

Elevate your career by leading Clinical Data Management initiatives, ensuring compliance and quality across clinical trials. Collaborate with cross-functional teams to drive data integrity and operati...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Take ownership of product strategy across diverse technologies, driving innovation in robotics and safety modules. Collaborate with leadership to translate market insights into actionable roadmaps, en...

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$196K - $243K *

Lead the charge in cross-functional delivery, managing prioritization and execution across diverse teams. Drive organizational effectiveness while fostering collaboration and trust, ensuring initiativ...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$235K - $255K *

Lead the HCP marketing strategy for a rare disease, driving engagement and collaboration with healthcare professionals. Oversee omnichannel initiatives, manage a team, and ensure compliance while opti...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $145K *

Lead the AirHub implementation, coordinating complex enterprise initiatives and ensuring operational readiness across cross-functional teams, from UAT to production rollouts, enhancing user support an...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$124K - $207K *

Champion innovative laboratory design and space planning, collaborating with R&D leaders to optimize environments that support scientific excellence and operational efficiency across a global portfoli...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$124K - $207K *

Drive laboratory design excellence by collaborating with R&D leaders to create innovative, flexible, and efficient lab environments that meet evolving scientific needs and uphold global design standar...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dynamic team to oversee acquisition management and support for mission planning systems, enhancing operational capabilities for the U.S. Air Force. Collaborate with stakeholders to ensure effec...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Empower the Aerospace Management Systems Division by providing expert program management support, ensuring effective acquisition strategies, and enhancing operational efficiency for critical air traff...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Join us to provide expert-level support to DoD acquisition programs, ensuring compliance and optimizing decision-making throughout the acquisition lifecycle. Your contributions will be vital in delive...

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Shape the future of defense by leading acquisition support for critical C3BM missions. Engage with diverse teams to manage programs that deliver integrated systems for operational excellence. Drive pr...

1 month ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive the strategy and execution of an AI framework for state government, ensuring responsible AI use and fostering innovation. Collaborate with stakeholders to implement effective AI initiatives that...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $145K *

Transform project delivery by leading strategies, budgets, and schedules. Serve as the primary client contact, ensuring seamless communication and collaboration across all phases of design and constru...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead complex product group initiatives, ensuring successful delivery through strategic planning, stakeholder engagement, and cross-team collaboration. Mentor program managers while driving transformat...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$156K - $195K *

Champion the global eDiscovery Technology practice, leading a diverse team to innovate AI-assisted workflows, ensuring defensibility and quality across jurisdictions while driving growth and operation...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$250K - $270K *

Lead the charge in enhancing the guest web ordering experience by managing a team of full-stack engineers. Drive product innovation, optimize conversion rates, and ensure engineering excellence across...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$86K - $129K *

Drive exceptional customer service for North American Solar accounts by coordinating field services, managing schedules, and ensuring effective communication between customers and internal teams. Your...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Empower project success through effective coordination and communication, ensuring client satisfaction and project completion on time and within budget. Be a key player in managing diverse teams and r...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$190K - $275K *

Lead the strategy and execution of AI and workflow capabilities, driving innovative solutions that enhance user experience and business outcomes across a scalable product suite. Mentor a team of Produ...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$105K - $130K *

Lead the proposal development process, enhancing strategies and systems to elevate submissions. Collaborate with executives and technical experts to create compelling, client-focused proposals that sh...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.