Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$225K - $265K *

Partner with us to lead a high-performing engineering team, driving innovation and efficiency in our travel marketplace. You'll manage project lifecycles, enhance collaboration, and champion a custome...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$158K - $237K *

Elevate your career by leading product management strategies and performance for cutting-edge semiconductor inspection solutions, driving successful customer adoption and collaboration across cross-fu...

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$158K - $237K *

Advance your career by leading product strategy and business performance in semiconductor inspection solutions. Drive product lifecycle management and engage with customers while managing cross-functi...

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$114K - $187K *

Champion clinical laboratory operations by managing complex projects, ensuring timely study starts, and collaborating with cross-functional teams to deliver impactful results in precision medicine...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$183K - $305K *

Pioneer operational leadership in drug development, guiding cross-functional teams to create strategic plans, manage budgets, and ensure timely execution from preclinical stages to commercialization w...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$200K - $350K *

Join a team that's dedicated to operational excellence in Management Consulting. Lead strategic initiatives, develop talent, and drive sustainable growth while ensuring consistent support for client-s...

4 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$157K - $283K *

Lead the charge in driving business growth by developing strategic partnerships and innovative solutions for federal clients, while collaborating with cross-functional teams to deliver exceptional res...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Drive the planning and execution of complex therapeutic programs from discovery to clinic. Serve as a senior program management partner, ensuring successful execution and alignment across cross-functi...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$104K - $111K *

Lead complex projects that drive organizational success, managing cross-functional teams and engaging stakeholders to achieve strategic goals. Foster a culture of continuous improvement and excellence...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $111K *

Join us to lead complex projects that drive strategic initiatives and foster continuous improvement. Collaborate with cross-functional teams and engage stakeholders to ensure project success and align...

Boston, MARemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$75K - $109K *

Shape your career by managing digital projects that blend technical skills with clinical expertise. Drive project goals, timelines, and budgets while ensuring high-quality deliverables and effective c...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$175K - $210K *

Lead global field operations, driving strategy and execution across sales, technical services, and partner functions. Collaborate with senior leadership to optimize pipeline management, forecasting, a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Transform automation capabilities by leading innovative engineering projects and collaborating across teams. Drive continuous improvement in operations and ensure regulatory compliance throughout proj...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Food & Beverages

$129K - $184K *

Elevate clinical data management by overseeing data integrity and quality across studies. Collaborate with cross-functional teams and vendors to ensure timely delivery of clinical data analyses, drivi...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the optimization of cross-pillar workflows, ensuring technical soundness and operational effectiveness. Collaborate with engineering and product teams to enhance product adoption and drive measur...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $217K *

Lead a dynamic team of engineering Scrum professionals to deliver high-quality, scalable software solutions by driving strategic initiatives and fostering a culture of technical excellence and operati...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$95K - $125K *

Advance your career by coordinating healthcare technology integration across multiple VA sites. Leverage your project management skills to support the Federal Electronic Health Record Modernization pr...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$128K - $178K *

Lead the charge in shaping the future of destination marketing through data-driven insights and innovative product strategies. Collaborate with cross-functional teams to enhance customer experiences a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$118K - $128K *

Elevate your career by driving program execution and performance management. Collaborate with cross-functional teams to ensure project success through effective risk management, forecasting, and stake...

4 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$93K - $116K *

Shape the future of project management by supporting senior leaders in overseeing project execution, coordinating teams, and ensuring effective communication. Drive project success through meticulous...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$216K - $236K *

Join a team that's redefining AI product management by driving ROI through innovative solutions. Lead the development of AI capabilities that enhance Alteryx workflows, ensuring faster, better, and ch...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$80K - $95K *

Take ownership of marketing project management by coordinating creative initiatives, optimizing workflows, and ensuring timely delivery of marketing assets across teams in a fast-paced environment...

1 week ago

  •   Less than 5 years exp.  •   Staffing

$230K - $263K *

Engage in driving complex technical initiatives and strategic API transformations. Collaborate with cross-functional teams to deliver high-impact projects, ensuring alignment with business objectives...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $195K *

Drive operational excellence and lead a high-performing team to deliver complex digital products. Collaborate with cross-functional teams to define strategies, manage resources, and ensure profitable...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $188K *

Engage in strategic program management to deliver complex initiatives and drive results across technology and business teams, ensuring project governance and success in achieving organizational object...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.