Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.
Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.
Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.
Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.
$170K - $180K *
Transform the sales landscape by leading strategic initiatives that enhance performance management, forecasting, and accountability across the commercial organization, driving profitable growth and ac...
2 weeks ago
Senior Engineering Manager, Agent Platform & Growth
$150K - $180K *
Join a team that's redefining the onboarding experience for human and AI agents by leading innovative UX and engineering teams. Drive growth through strategic roadmap ownership, hands-on leadership, a...
Reposted 3 weeks ago
$150K - $180K *
Manage financial planning and performance analysis for the GTM organization, partnering with leadership across Sales, Marketing, and Customer Success to drive revenue growth and profitability through...
3 weeks ago
$90K - $110K *
Grow your career with a dynamic HR leadership role that champions culture, drives talent strategies, and ensures compliance while fostering a positive workplace. Collaborate with executives to align H...
4 days ago
$125K - $150K *
Unlock potential by driving client success through expert system configuration, data analysis, and consultative training. Ensure timely project delivery while enhancing user experience and satisfactio...
Reposted 2 weeks ago
Senior Advisor, Sponsored Projects & Funds
$135K - $145K *
Advance your career by leading strategic partnerships and managing fiscal sponsorship projects. Collaborate with clients and stakeholders to ensure successful outcomes while providing expert guidance...
2 weeks ago
Program Manager, Provider Partnerships
$110K - $130K *
Architect scalable provider programs by turning individual relationships into streamlined systems. Oversee the complete lifecycle, maintain compliance, and manage flagship programs while collaborating...
Reposted 4 weeks ago
$150K - $180K *
Join a team that's redefining scientific data management in drug discovery. Lead the scientific data team, bridging scientists and engineers to ensure data integrity, quality, and innovative solutions...
2 weeks ago
$80K - $95K *
Take ownership of payroll operations, ensuring accuracy and compliance while leading a team to deliver timely wage payments and manage tax obligations effectively across the organization...
Today
$120K - $140K *
Shape the future of federal financial operations by driving user adoption and change management for a new tool. Collaborate with stakeholders to enhance user experience, streamline processes, and ensu...
4 days ago
$70K - $140K *
Lead the charge in enhancing our Partner ecosystem by managing relationships and driving growth initiatives. Oversee onboarding, operations, and support for System Integrators while implementing autom...
Reposted 2 weeks ago
$110K - $130K *
Manage a dedicated team to enhance patient access to complex medications, ensuring operational excellence and compliance while delivering exceptional experiences. Guide strategic improvements to optim...
Reposted 2 weeks ago
Sr. Director, Scientific Affairs
$181K - $225K *
Lead the charge in operationalizing complex clinical studies globally, collaborating with cross-functional teams to enhance proposal development and manage global lab relationships, ensuring strategic...
2 weeks ago
Sr. Director, Scientific Affairs
$181K - $225K *
Lead the charge in advancing scientific operations within a dynamic team, driving global lab relationships and supporting complex clinical studies. Collaborate across functions to ensure strategic, op...
2 weeks ago
$125K - $150K *
Lead the charge in managing high-impact capital projects and engineering staff. Drive innovation and efficiency at our manufacturing facility while ensuring compliance with CGMP and ISO standards. Emp...
Reposted 1 week ago
Principal Group Product Manager- AL Labs
$170K - $243K *
Transform product innovation by leading AI-driven strategies and experiments, collaborating across teams to enhance software solutions and improve employee experiences in a dynamic, fast-paced environ...
3 days ago
Product Owner 360e Facility Coding
$125K - $172K *
Unlock potential by leading product initiatives for 360e Facility Coding, collaborating with diverse teams to enhance customer experiences and drive business value through innovative solutions and eff...
Today
Director, Business Development
$150K - $180K *
Unlock new opportunities as you drive business growth in the life sciences sector. Focus on building relationships and matching client needs with innovative solutions in commercial consulting, brand c...
Reposted 3 weeks ago
Director of Software Engineering, Platform Services
$208K - $306K *
Join a team that's redefining engineering excellence by leading platform services that enhance software development. Drive innovation, consolidate capabilities, and foster a culture of collaboration t...
3 weeks ago
1557- Director, Strategic Sourcing- Corporate Services
$125K - $185K *
Transform strategic sourcing for HR and Benefits, leading complex engagements and driving cost savings while ensuring high supplier performance and stakeholder satisfaction across diverse client needs...
4 days ago
Design Manager - Nuclear Facilities
$134K - $241K *
Shape the future of nuclear facilities by leading a team to design innovative fuel production and waste processing facilities. Drive compliance and efficiency while collaborating on large-scale projec...
1 month ago
$183K - $215K *
Shape the future of North American inland transportation by leading product strategy and development. Collaborate with cross-functional teams to deliver actionable insights and drive market success in...
Today
$250K - $275K *
Empower the data landscape by leading a team to create reliable, AI-ready data systems. Own the data platform, establish governance, and ensure data quality for impactful decision-making across client...
1 week ago
$150K - $180K *
Transform client relationships and drive strategic practice growth by developing goals, managing consulting services, and executing sales strategies within a collaborative, innovative environment to m...
Reposted 4 weeks ago
$188K - $245K *
Drive innovative UX design strategies in clinical settings, leading a talented team to enhance decision support and care coordination. Collaborate across functions to integrate AI and elevate user exp...
3 weeks ago
What types of $100,000+ jobs can I find in Kentucky?
Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.
Which Kentucky cities have professional job opportunities?
Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.
Do jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.
How can I find a high-paying job in Kentucky?
Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.