Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
$90K - $110K *
Accelerate program implementation and stakeholder engagement in pharmaceutical market access. Oversee daily operations, client relations, and staff management while ensuring adherence to budgets and p...
Reposted 3 weeks ago
Principal Cloud Operations Manager
$165K - $248K *
Lead enterprise-scale operations for cloud services, ensuring performance and customer satisfaction. Drive a multidisciplinary team, manage service transitions, and leverage data-driven metrics to enh...
Reposted 2 weeks ago
Lead Project Manager, Delivery
$115K - $158K *
Join a team that's driving innovation in project management for enterprise decisioning. Collaborate across business and technology teams to ensure successful delivery of complex initiatives while main...
Yesterday
$117K - $158K *
Unlock potential by leading complex client engagements, ensuring timely delivery, budget management, and effective resource utilization while navigating challenges in a dynamic environment. Empower te...
4 weeks ago
Sr. Director, Product Management - DealCloud for Legal
$160K - $190K *
Shape the future of legal technology by leading product strategy and development for innovative SaaS solutions. Collaborate with cross-functional teams to enhance user experience and drive market diff...
2 weeks ago
$110K - $130K *
Lead the charge in executing healthcare projects, overseeing feasibility, design, and construction processes while ensuring budget adherence and client satisfaction through effective collaboration and...
3 weeks ago
$135K - $227K *
Lead the strategy and execution of workforce management for customer operations, optimizing staffing and performance through data-driven insights. Collaborate with senior leaders to enhance service le...
2 weeks ago
Anaplan Product Owner, Manager
$91K - $190K *
Drive the charge in advancing Anaplan strategies, leading diverse teams to optimize solutions that align with business objectives. Collaborate with stakeholders to enhance the Anaplan ecosystem and en...
Today
Senior Principal Portfolio and Offer Management
$170K - $200K *
Drive portfolio strategy and execution by transforming market needs into profitable offers. Collaborate across teams to ensure alignment and operational readiness, enhancing sales confidence and optim...
3 weeks ago
Principal Engineer, Transformation Engineering
$131K - $196K *
Unlock potential by developing AI-driven applications and data pipelines. Collaborate with teams to enhance operational efficiency through innovative technical solutions, ensuring quality and scalabil...
6 days ago
$100K - $120K *
Empower a dynamic team to create impactful product education strategies, ensuring effective training delivery for customers and partners. Collaborate across departments to enhance learning paths and c...
5 days ago
Senior Director, Regional Governance
$185K - $231K *
Unlock potential by leading regional service delivery, driving growth and operational excellence across multiple territories. Collaborate with diverse teams to enhance customer satisfaction and optimi...
2 weeks ago
$85K - $95K *
Transform processes and drive accountability by leading cross-functional projects. Manage initiatives from scoping to completion while maintaining clear communication across teams and ensuring stakeho...
4 weeks ago
$120K - $145K *
Champion the management of IT infrastructure and security, driving compliance and AI initiatives. This hands-on role requires direct involvement in operations, ensuring robust cybersecurity and effici...
3 weeks ago
Senior Program Delivery Manager - Strategic Supplier Program
$120K - $145K *
Empower senior leadership by driving delivery strategies for a large-scale supplier program. Collaborate with stakeholders to ensure alignment, mitigate risks, and optimize outcomes while maintaining...
Today
Manager - Data Engineering & Operations
$100K - $120K *
Transform data operations by architecting scalable solutions that enhance fan engagement and analytics. Collaborate across teams to integrate systems, ensure data integrity, and drive AI initiatives...
3 weeks ago
Senior Design Program Manager II
$167K - $176K *
Shape the future of design operations by driving program execution, leveraging AI for efficiency, and managing cross-functional partnerships to enhance creative workflows and deliver impactful design...
Reposted 1 week ago
$90K - $110K *
Join a team that's dedicated to delivering successful large-scale projects. Oversee all phases from planning to execution, ensuring timely completion and budget adherence while fostering strong custom...
6 days ago
Executive Director, Patient Solutions Operations
$160K - $200K *
Lead the operational execution of a patient support program, ensuring high-quality service delivery and compliance. Drive strategic planning, team development, and continuous improvement initiatives t...
1 week ago
Executive Director, Patient Solutions Operations
$160K - $190K *
Drive operational excellence in patient support programs, enhancing access and outcomes through strategic leadership, compliance, and team development. Oversee key functions to ensure a patient-center...
1 week ago
PPM Director - PPM Tool, Data, Reporting
$140K - $215K *
Drive the execution of business-specific IS strategy as the PPM Tool Product Owner, managing system enhancements, team performance, and change management initiatives to align with organizational goals...
1 week ago
Rack Integration Project & Program Manager
$92K - $154K *
Champion end-to-end program delivery for rack integration operations, ensuring seamless production scheduling, materials coordination, and quality assurance while collaborating with cross-functional t...
1 week ago
$242K - $282K *
Lead the oversight of contractual matters across departments, serving as a trusted advisor to internal stakeholders from pre-clinical to commercial readiness. This role emphasizes collaboration and ex...
Reposted 3 weeks ago
Director, Program Management Strategic Capital Project (North Carolina)
$135K - $160K *
Lead cross-functional collaboration to ensure seamless execution of strategic projects, monitoring performance and Initial Manufacturing expenses, while driving innovation through AI tools and harmoni...
4 weeks ago
Product Manager, Ignite Member Operations
$125K - $141K *
Lead the product direction for membership operations, balancing customer needs and enterprise requirements. Collaborate with teams to enhance workflows, improve operational outcomes, and ensure a seam...
Yesterday
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.