Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$90K - $110K *

Accelerate program implementation and stakeholder engagement in pharmaceutical market access. Oversee daily operations, client relations, and staff management while ensuring adherence to budgets and p...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$165K - $248K *

Lead enterprise-scale operations for cloud services, ensuring performance and customer satisfaction. Drive a multidisciplinary team, manage service transitions, and leverage data-driven metrics to enh...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$115K - $158K *

Join a team that's driving innovation in project management for enterprise decisioning. Collaborate across business and technology teams to ensure successful delivery of complex initiatives while main...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$117K - $158K *

Unlock potential by leading complex client engagements, ensuring timely delivery, budget management, and effective resource utilization while navigating challenges in a dynamic environment. Empower te...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$160K - $190K *

Shape the future of legal technology by leading product strategy and development for innovative SaaS solutions. Collaborate with cross-functional teams to enhance user experience and drive market diff...

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the charge in executing healthcare projects, overseeing feasibility, design, and construction processes while ensuring budget adherence and client satisfaction through effective collaboration and...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $227K *

Lead the strategy and execution of workforce management for customer operations, optimizing staffing and performance through data-driven insights. Collaborate with senior leaders to enhance service le...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$91K - $190K *

Drive the charge in advancing Anaplan strategies, leading diverse teams to optimize solutions that align with business objectives. Collaborate with stakeholders to enhance the Anaplan ecosystem and en...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$170K - $200K *

Drive portfolio strategy and execution by transforming market needs into profitable offers. Collaborate across teams to ensure alignment and operational readiness, enhancing sales confidence and optim...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$131K - $196K *

Unlock potential by developing AI-driven applications and data pipelines. Collaborate with teams to enhance operational efficiency through innovative technical solutions, ensuring quality and scalabil...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$100K - $120K *

Empower a dynamic team to create impactful product education strategies, ensuring effective training delivery for customers and partners. Collaborate across departments to enhance learning paths and c...

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$185K - $231K *

Unlock potential by leading regional service delivery, driving growth and operational excellence across multiple territories. Collaborate with diverse teams to enhance customer satisfaction and optimi...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$85K - $95K *

Transform processes and drive accountability by leading cross-functional projects. Manage initiatives from scoping to completion while maintaining clear communication across teams and ensuring stakeho...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Champion the management of IT infrastructure and security, driving compliance and AI initiatives. This hands-on role requires direct involvement in operations, ensuring robust cybersecurity and effici...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Empower senior leadership by driving delivery strategies for a large-scale supplier program. Collaborate with stakeholders to ensure alignment, mitigate risks, and optimize outcomes while maintaining...

Today

  •   8 - 10 years exp.  •   Staffing

$100K - $120K *

Transform data operations by architecting scalable solutions that enhance fan engagement and analytics. Collaborate across teams to integrate systems, ensure data integrity, and drive AI initiatives...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$167K - $176K *

Shape the future of design operations by driving program execution, leveraging AI for efficiency, and managing cross-functional partnerships to enhance creative workflows and deliver impactful design...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $110K *

Join a team that's dedicated to delivering successful large-scale projects. Oversee all phases from planning to execution, ensuring timely completion and budget adherence while fostering strong custom...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$160K - $200K *

Lead the operational execution of a patient support program, ensuring high-quality service delivery and compliance. Drive strategic planning, team development, and continuous improvement initiatives t...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Drive operational excellence in patient support programs, enhancing access and outcomes through strategic leadership, compliance, and team development. Oversee key functions to ensure a patient-center...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$140K - $215K *

Drive the execution of business-specific IS strategy as the PPM Tool Product Owner, managing system enhancements, team performance, and change management initiatives to align with organizational goals...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$92K - $154K *

Champion end-to-end program delivery for rack integration operations, ensuring seamless production scheduling, materials coordination, and quality assurance while collaborating with cross-functional t...

North Carolina, USRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$242K - $282K *

Lead the oversight of contractual matters across departments, serving as a trusted advisor to internal stakeholders from pre-clinical to commercial readiness. This role emphasizes collaboration and ex...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead cross-functional collaboration to ensure seamless execution of strategic projects, monitoring performance and Initial Manufacturing expenses, while driving innovation through AI tools and harmoni...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $141K *

Lead the product direction for membership operations, balancing customer needs and enterprise requirements. Collaborate with teams to enhance workflows, improve operational outcomes, and ensure a seam...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.