Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Senior Technical Project Manager
$110K - $130K *
Empower the future of technology delivery in financial services by leading cross-functional teams to execute strategic initiatives, ensuring high-quality releases that align with business priorities a...
3 weeks ago
Senior Director, Global Field Operations
$175K - $210K *
Lead global field operations, driving strategy and execution across sales, technical services, and partner functions. Collaborate with senior leadership to optimize pipeline management, forecasting, a...
2 weeks ago
Director, Commercial Project Management
$201K - $251K *
Join us to lead cross-functional project management in a dynamic biotech environment. Drive global commercialization initiatives, ensuring alignment and execution across teams while enhancing operatio...
2 weeks ago
Director, People Business Partner - Product, Technology & AI
$150K - $180K *
Transform the future of talent management by partnering with Product and Technology leaders to design and implement a GM operating model, ensuring effective organizational strategies and people practi...
1 week ago
Program Manager, Enterprise Growth & Capital Programs
$100K - $180K *
Lead the charge in delivering enterprise-level growth programs by ensuring alignment across all functions, driving planning and execution adherence, and managing complex initiatives for timely product...
Reposted 1 week ago
Senior Technical Program Manager
$200K - $220K *
Empower the future of financial operations by mastering money movement, ensuring seamless transactions and transparency. Collaborate with cross-functional teams to drive product success and enhance cl...
2 weeks ago
$80K - $121K *
Champion legal operations excellence by driving process improvements, metrics establishment, and AI integration to enhance workflow efficiencies and support the Legal team in dynamic, fast-paced envir...
Reposted 3 weeks ago
Director, Technology Delivery and Release Management
$184K - $225K *
Champion delivery excellence and release governance across technology portfolios. Drive operational readiness and continuous improvement while collaborating with stakeholders to ensure predictable out...
1 week ago
Associate Director, Strategic Program Management
$120K - $145K *
Drive strategic program management by leading cross-functional teams to execute complex global projects, balancing business strategy with program execution to achieve transformative results and ensure...
Today
$125K - $150K *
Shape the future of biopharmaceuticals by leading our Program Management team. Drive program success from contract to closure, ensuring quality and customer satisfaction while fostering a high-perform...
2 weeks ago
Director, Production and Infrastructure Engineering
$240K - $290K *
Elevate your career by leading a dynamic engineering team focused on production and infrastructure. Drive performance, foster collaboration, and deliver innovative solutions while managing diverse tec...
2 days ago
$150K - $170K *
Lead the charge in delivering high-impact project management services, overseeing a remote PMO team to ensure alignment with organizational goals, while driving stakeholder communication and adapting...
Reposted 1 month ago
$160K - $297K *
Join us to lead the evolution of product operations, enhancing collaboration across teams and driving measurable outcomes through innovative processes and AI-enabled workflows. Your expertise will sha...
Today
Senior Project Manager, Promotional Medical Education
$90K - $100K *
Accelerate progress at a dynamic agency by leading complex client campaigns. Manage project scope, timelines, and budgets while collaborating with cross-functional teams to deliver high-quality result...
Reposted 1 week ago
Senior Program Manager, Medical Product Development
$160K - $215K *
Lead and innovate in medical product development, managing a diverse portfolio of projects. Collaborate with multidisciplinary teams to drive scientific objectives, ensure accountability, and navigate...
2 weeks ago
Senior Program Manager - Data Security & Information Governance
$135K - $178K *
Transform data governance by leading initiatives that bridge legal compliance, data security, and technology operations. Drive innovative self-service workflows while ensuring compliance across divers...
Reposted 5 days ago
$155K - $410K *
Shape large-scale SAP implementations by defining objectives, managing resources, and guiding cross-functional teams. Lead strategic direction, mentor future leaders, and drive innovation to enhance o...
1 week ago
$155K - $410K *
Shape the future of SAP implementation by leading large-scale programs, defining strategic objectives, and mentoring teams to drive operational efficiency and client success across multiple engagement...
1 week ago
$155K - $410K *
Shape the future of SAP solutions by leading large-scale implementations, guiding teams, and driving strategic direction while fostering client relationships and mentoring future leaders in a dynamic...
1 week ago
CEx Program Management Manager, HSDC
$137K - $189K *
Join a team that's dedicated to strategic account management, ensuring customer satisfaction through collaboration with cross-functional teams. Drive continuous improvement and enhance customer experi...
Reposted 1 week ago
Director- SW Software Portfolio Excellence
$150K - $180K *
Champion cross-functional excellence by driving strategic software portfolio initiatives, aligning teams, and ensuring accountability for measurable business outcomes...
4 weeks ago
$110K - $130K *
Elevate your career by leading a technical team to enhance collaboration tools in a dynamic, cloud-based environment. Engage with federal clients, drive Agile practices, and ensure toolset efficiency...
1 month ago
$90K - $140K *
Join a team that's driving project success by leading technical initiatives, resolving complex challenges, and aligning outcomes with client objectives. Your expertise will enhance profitability and o...
1 week ago
$171K - $202K *
Drive the creation and oversight of a risk framework that balances growth with security. Partner with cross-functional teams to implement risk strategies operationally, while conveying insights to exe...
1 month ago
$110K - $130K *
Lead the charge in overseeing high-impact projects, driving strategic initiatives, and fostering strong customer relationships while ensuring alignment with business objectives and delivering measurab...
Reposted 2 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.