Explore $100K+ Jobs in Michigan

Discover professional opportunities across Michigan with Ladders, where job seekers can explore vetted roles offering salaries of $100,000 or more. From established employers in Detroit to growing companies in Grand Rapids, Ann Arbor, Lansing, and other communities, Michigan offers career paths across a diverse range of industries and leadership levels.

Find Opportunities Across Michigan

Search jobs throughout the state, including major employment hubs such as Detroit, Grand Rapids, Ann Arbor, Lansing, and Kalamazoo. Depending on the role and employer, opportunities may offer on-site, hybrid, or remote work arrangements. Review each listing for location, compensation, responsibilities, and workplace expectations.

Explore Michigan Industries

Michigan is known for its automotive and advanced manufacturing industries, while also supporting opportunities in technology, healthcare, finance, engineering, supply chain, energy, and professional services. Employers seek experienced professionals for specialized individual-contributor roles as well as management and executive positions.

Build Your Next Career Move

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Compare opportunities, identify roles that fit your experience, and tailor your résumé to highlight measurable results, leadership, and relevant expertise. Job availability and compensation vary by employer, location, and qualifications.

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$245K - $286K *

Elevate clinical quality assurance through strategic leadership and oversight of global trials, ensuring compliance with GCP regulations. Drive quality culture and inspection readiness while mentoring...

United StatesRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$238K - $298K *

Drive the vision and strategy for autonomy behaviors, leading teams to innovate and enhance advanced decision-making technologies. Collaborate cross-functionally to tackle challenges and ensure effici...

Reposted 1 month ago

  •   5 - 7 years exp.  •   Transportation

$110K - $130K *

Lead strategic initiatives in manufacturing optimization, driving cost efficiency and capacity management while coordinating cross-functional projects to enhance operational performance and support ne...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$114K - $165K *

Join our dynamic team to lead the development of high-performance backend solutions. Leverage your expertise in Java, microservices, and real-time data streaming to drive innovation and mentor a talen...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$94K - $148K *

Join a team that's redefining technology sourcing strategies to drive savings and innovation. Lead cross-functional collaboration, manage supplier performance, and coach a talented team to optimize te...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$91K - $169K *

Shape the future of compliance in AI by leading product roadmaps that ensure trust and security. Collaborate with cross-functional teams to translate regulatory requirements into actionable product fe...

3 days ago

  •   Less than 5 years exp.  •   Media

$110K - $130K *

Unlock potential by leading a global team in Trust Services, enhancing client relationships, and driving operational excellence. Shape the future of AI-powered security solutions while ensuring top-ti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Drive operational excellence by leading the S&OP strategy, aligning resources with business goals, and optimizing capacity planning across the network to enhance efficiency and service delivery...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$130K *

Drive innovation in healthcare technology by leading product management efforts, connecting cross-functional teams, and shaping the product roadmap to enhance value-based care solutions. Engage hands...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$82K - $115K *

Optimize project execution by managing change processes, evaluating cost variances, and collaborating with stakeholders to ensure timely and effective project delivery while mitigating risks and enhan...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$172K - $287K *

Join us to shape the future of pharmacy by leading product strategy and innovation. Drive growth and commercialization for a diverse portfolio of healthcare technology solutions, influencing enterpris...

RemoteRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Transform the data platform by owning product direction and delivery. Collaborate across teams to prioritize needs, streamline processes, and ensure engineering focuses on impactful projects while enh...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$220K - $260K *

Transform your career by leading product strategy and execution for payment solutions. Drive innovation in payment workflows, enhance reliability, and optimize operational efficiency while collaborati...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$285K - $325K *

Drive transformational patient impact by leading cross-functional teams and executing strategic drug development programs in an agile environment. Foster collaboration and accountability to deliver in...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $228K *

Engage with customers to shape the future of Hyperscale Data Center networks. Lead architecture discussions, drive technology roadmaps, and collaborate with teams to deliver scalable, high-performance...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$270K - $280K *

Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $151K *

Drive product strategy and execution for Patient Experience solutions, enhancing healthcare practices' connection with patients. Lead cross-functional teams, leverage AI, and optimize workflows to imp...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Engage with clients to design and implement tailored Manhattan WMS solutions, ensuring optimal performance and support throughout the project lifecycle. Leverage your expertise to transform supply cha...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$154K - $193K *

Shape the future of public sector transformation by leading Organizational Change Management and training initiatives. Collaborate with stakeholders to ensure successful adoption of new systems and pr...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$155K - $160K *

Drive the data and AI strategy by collaborating with clients, shaping predictive roadmaps, and translating complex problems into actionable product development, enhancing customer-facing analytics and...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$155K - $170K *

Lead the charge in shaping enterprise business solutions through hands-on architecture and delivery in Microsoft Dynamics 365 Finance & Operations, focusing on integration, process optimization, and o...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Staffing

$135K - $160K *

Lead the charge in transforming data accessibility for product teams and AI agents. Oversee a team of data engineers to build a robust platform that ensures secure, reliable data usage across the orga...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$73K - $120K *

Drive the success of inpatient Payment Integrity programs by overseeing audits, ensuring compliance, and enhancing quality across teams and vendors. Collaborate with stakeholders to optimize processes...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in MEP project management, driving design collaboration and cost analysis while fostering an inclusive team environment. Oversee project workflows, mitigate risks, and ensure effective...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Drive material handling automation projects by managing diverse equipment, software, and technologies. Oversee project execution, financials, and vendor relationships while ensuring adherence to stand...

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Michigan?question toggle

    Listings may include senior and executive roles in fields such as engineering, technology, healthcare, finance, manufacturing, supply chain, and professional services. Available positions vary over time.

  • Which Michigan cities have professional job opportunities?question toggle

    Opportunities can be found in Detroit, Grand Rapids, Ann Arbor, Lansing, Kalamazoo, and other Michigan communities. Search by location to find roles that match your preferences.

  • Are Michigan jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Check individual listings for details about the employer, role, location, and compensation.

  • Do Michigan jobs offer remote or hybrid work?question toggle

    Some employers may offer remote or hybrid arrangements, while others require on-site work. Review each job listing for its specific work-location expectations.