Discover professional opportunities across Michigan with Ladders, where job seekers can explore vetted roles offering salaries of $100,000 or more. From established employers in Detroit to growing companies in Grand Rapids, Ann Arbor, Lansing, and other communities, Michigan offers career paths across a diverse range of industries and leadership levels.
Search jobs throughout the state, including major employment hubs such as Detroit, Grand Rapids, Ann Arbor, Lansing, and Kalamazoo. Depending on the role and employer, opportunities may offer on-site, hybrid, or remote work arrangements. Review each listing for location, compensation, responsibilities, and workplace expectations.
Michigan is known for its automotive and advanced manufacturing industries, while also supporting opportunities in technology, healthcare, finance, engineering, supply chain, energy, and professional services. Employers seek experienced professionals for specialized individual-contributor roles as well as management and executive positions.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Compare opportunities, identify roles that fit your experience, and tailor your résumé to highlight measurable results, leadership, and relevant expertise. Job availability and compensation vary by employer, location, and qualifications.
Senior Director, Clinical Quality Assurance (CQA)
$245K - $286K *
Elevate clinical quality assurance through strategic leadership and oversight of global trials, ensuring compliance with GCP regulations. Drive quality culture and inspection readiness while mentoring...
Reposted 4 weeks ago
$238K - $298K *
Drive the vision and strategy for autonomy behaviors, leading teams to innovate and enhance advanced decision-making technologies. Collaborate cross-functionally to tackle challenges and ensure effici...
Reposted 1 month ago
North America MFG Planning Manager
$110K - $130K *
Lead strategic initiatives in manufacturing optimization, driving cost efficiency and capacity management while coordinating cross-functional projects to enhance operational performance and support ne...
3 weeks ago
$114K - $165K *
Join our dynamic team to lead the development of high-performance backend solutions. Leverage your expertise in Java, microservices, and real-time data streaming to drive innovation and mentor a talen...
Reposted today
Senior Manager, Technology Category Management
$94K - $148K *
Join a team that's redefining technology sourcing strategies to drive savings and innovation. Lead cross-functional collaboration, manage supplier performance, and coach a talented team to optimize te...
3 days ago
Product Manager, Compliance Products Government
$91K - $169K *
Shape the future of compliance in AI by leading product roadmaps that ensure trust and security. Collaborate with cross-functional teams to translate regulatory requirements into actionable product fe...
3 days ago
Senior Manager, Trust Services
$110K - $130K *
Unlock potential by leading a global team in Trust Services, enhancing client relationships, and driving operational excellence. Shape the future of AI-powered security solutions while ensuring top-ti...
1 week ago
Director, Sales & Operations Planning
$150K - $180K *
Drive operational excellence by leading the S&OP strategy, aligning resources with business goals, and optimizing capacity planning across the network to enhance efficiency and service delivery...
1 week ago
Senior Product Manager, Value-Based Care Platforms
$130K *
Drive innovation in healthcare technology by leading product management efforts, connecting cross-functional teams, and shaping the product roadmap to enhance value-based care solutions. Engage hands...
3 days ago
Change Management Project Manager
$82K - $115K *
Optimize project execution by managing change processes, evaluating cost variances, and collaborating with stakeholders to ensure timely and effective project delivery while mitigating risks and enhan...
1 week ago
Senior Director Product Management
$172K - $287K *
Join us to shape the future of pharmacy by leading product strategy and innovation. Drive growth and commercialization for a diverse portfolio of healthcare technology solutions, influencing enterpris...
Reposted 2 weeks ago
Technical Product Manager, Data Platform
$120K - $145K *
Transform the data platform by owning product direction and delivery. Collaborate across teams to prioritize needs, streamline processes, and ensure engineering focuses on impactful projects while enh...
2 weeks ago
$220K - $260K *
Transform your career by leading product strategy and execution for payment solutions. Drive innovation in payment workflows, enhance reliability, and optimize operational efficiency while collaborati...
3 weeks ago
Program Executive, Drug Development and Commercial
$285K - $325K *
Drive transformational patient impact by leading cross-functional teams and executing strategic drug development programs in an agile environment. Foster collaboration and accountability to deliver in...
Reposted 2 weeks ago
Director, Data Center Solutions Architect
$165K - $228K *
Engage with customers to shape the future of Hyperscale Data Center networks. Lead architecture discussions, drive technology roadmaps, and collaborate with teams to deliver scalable, high-performance...
2 days ago
Senior Director, Clinical Operations
$270K - $280K *
Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...
3 weeks ago
$135K - $151K *
Drive product strategy and execution for Patient Experience solutions, enhancing healthcare practices' connection with patients. Lead cross-functional teams, leverage AI, and optimize workflows to imp...
3 days ago
$90K - $110K *
Engage with clients to design and implement tailored Manhattan WMS solutions, ensuring optimal performance and support throughout the project lifecycle. Leverage your expertise to transform supply cha...
Reposted 3 days ago
$154K - $193K *
Shape the future of public sector transformation by leading Organizational Change Management and training initiatives. Collaborate with stakeholders to ensure successful adoption of new systems and pr...
3 weeks ago
Technical Product Manager - AI & Data Analytics
$155K - $160K *
Drive the data and AI strategy by collaborating with clients, shaping predictive roadmaps, and translating complex problems into actionable product development, enhancing customer-facing analytics and...
Reposted 2 weeks ago
Director, Business Systems & Solution Architecture (D365 F&O)
$155K - $170K *
Lead the charge in shaping enterprise business solutions through hands-on architecture and delivery in Microsoft Dynamics 365 Finance & Operations, focusing on integration, process optimization, and o...
Reposted 2 weeks ago
Senior Manager, Data Engineering
$135K - $160K *
Lead the charge in transforming data accessibility for product teams and AI agents. Oversee a team of data engineers to build a robust platform that ensures secure, reliable data usage across the orga...
5 days ago
Payment Integrity Program Manager
$73K - $120K *
Drive the success of inpatient Payment Integrity programs by overseeing audits, ensuring compliance, and enhancing quality across teams and vendors. Collaborate with stakeholders to optimize processes...
3 weeks ago
$95K - $115K *
Lead the charge in MEP project management, driving design collaboration and cost analysis while fostering an inclusive team environment. Oversee project workflows, mitigate risks, and ensure effective...
Reposted 5 days ago
Sr. Project Manager-Intralogistics
$95K - $115K *
Drive material handling automation projects by managing diverse equipment, software, and technologies. Oversee project execution, financials, and vendor relationships while ensuring adherence to stand...
Yesterday
What kinds of $100,000+ jobs can I find in Michigan?
Listings may include senior and executive roles in fields such as engineering, technology, healthcare, finance, manufacturing, supply chain, and professional services. Available positions vary over time.
Which Michigan cities have professional job opportunities?
Opportunities can be found in Detroit, Grand Rapids, Ann Arbor, Lansing, Kalamazoo, and other Michigan communities. Search by location to find roles that match your preferences.
Are Michigan jobs on Ladders vetted?
Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Check individual listings for details about the employer, role, location, and compensation.
Do Michigan jobs offer remote or hybrid work?
Some employers may offer remote or hybrid arrangements, while others require on-site work. Review each job listing for its specific work-location expectations.