Director of Operational Excellence Jobs

Discover Director of Operational Excellence opportunities on Ladders, where professionals can explore vetted jobs paying $100,000 or more. These senior leaders help organizations improve performance, streamline processes, and build a culture of continuous improvement. Roles span industries and may focus on enterprise transformation, quality, supply chain, manufacturing, healthcare, technology, or business operations.

What Does a Director of Operational Excellence Do?

A Director of Operational Excellence develops and leads initiatives that make an organization more effective, resilient, and customer-focused. Responsibilities often include identifying process gaps, setting improvement priorities, establishing performance measures, and partnering with executives and operational teams to deliver sustainable results. Depending on the employer, the role may oversee Lean, Six Sigma, change management, process design, or operational transformation programs.

Skills and Qualifications Employers Seek

Employers commonly look for strategic leadership, analytical problem-solving, change management, and the ability to influence across departments. Experience with continuous improvement methods such as Lean or Six Sigma, along with data analysis, project portfolio management, and KPI development, can be valuable. Many positions require a bachelor’s degree and substantial relevant experience; some prefer an advanced degree or professional certification.

Industries and Career Opportunities

Director of Operational Excellence roles are available in sectors where reliable, efficient processes are critical, including manufacturing, healthcare, financial services, logistics, retail, and technology. The scope varies: some directors lead improvement teams at a single site, while others shape operating models and transformation efforts across multiple business units or global organizations. Career paths may lead to vice president of operations, chief operating officer, or enterprise transformation leadership.

Find Director of Operational Excellence Jobs on Ladders

Use Ladders to explore vetted senior-level opportunities with salaries of $100,000 or more. Compare roles by industry, location, and scope, and look for positions that match your experience in operational strategy, process improvement, and executive leadership.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
More
1
caret down

$149K - $224K *

Drive analytics excellence by leading a team to deliver impactful insights, enhance reporting capabilities, and support strategic decision-making across diverse business functions. Foster collaboratio...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$76K - $127K *

Unlock growth by collaborating with cross-functional teams to drive market strategies, analyze data, and enhance customer engagement in the healthcare ecosystem. Contribute to impactful marketing init...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive operational excellence by overseeing program management activities, supervising a dedicated team, and ensuring adherence to policies and procedures. Collaborate with stakeholders to enhance effi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Help us drive business development in oncology by leading strategic partnerships and optimizing resources to enhance clinical outcomes and market potential for our innovative diagnostic and therapeuti...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K *

Drive your career by leading technical architecture and AI tooling development in a dynamic company transitioning to multi-platform solutions. Collaborate with teams, mentor talent, and engage with en...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$132K - $182K *

Drive program execution across high-priority workstreams in Customer Outcomes, managing threat intelligence partnerships and AI model initiatives. Collaborate with cross-functional teams to ensure tim...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Optimize runtime authorization strategies across diverse segments, driving technical wins and enabling Sales Engineers. Leverage deep IAM and PAM expertise to deliver impactful solutions, ensuring com...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$142K - $234K *

Shape the future of technology risk management by leading initiatives that enhance security, resilience, and innovation. Collaborate with cross-functional teams to embed risk practices and drive scala...

California, USRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in market intelligence and sales support, bridging teams to drive insights and strategies in U.S. power markets. Collaborate cross-functionally to identify opportunities and enhance cu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$82K - $182K *

Lead strategic initiatives by connecting technology investments to business goals, ensuring effective governance and measurable outcomes. Collaborate cross-functionally to enhance operational efficien...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $223K *

Transform territory management by leading sales initiatives, building client relationships, and collaborating cross-functionally to achieve growth and profitability targets in the healthcare sector...

San Diego, CARemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Lead transformative facilities initiatives by analyzing data, optimizing performance, and managing capital projects. Collaborate across teams to drive efficiency, reduce costs, and enhance restaurant...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$120K - $145K *

Transform global partner marketing strategies to drive growth and engagement. Collaborate with cross-functional teams to execute integrated campaigns and optimize performance across diverse markets, e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$130K - $170K *

Transform procurement strategies globally by leading a dynamic team, collaborating with finance and legal, and optimizing vendor relationships to drive operational efficiency and cost savings across a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $170K *

Join a team that's shaping healthcare innovation through AI-driven voice solutions. Lead a distributed engineering team to deliver high-quality software and collaborate with cross-functional stakehold...

CanadaRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$195K - $245K *

Champion AI strategy and implementation in healthcare, leading a team to deliver measurable value. Drive business development, client engagement, and practice growth while shaping innovative solutions...

Chicago, ILRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$107K - $147K *

Unlock potential by partnering with clients to implement CDI solutions, optimize workflows, and enhance client satisfaction. Leverage your expertise to drive change and ensure best practices in health...

Pittsburgh, PARemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$196K - $243K *

Lead the charge in cross-functional delivery, managing prioritization and execution across diverse teams. Drive organizational effectiveness while fostering collaboration and trust, ensuring initiativ...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$75K - $105K *

Tackle comprehensive project management for onboarding HME providers, driving digital transformation across healthcare. Collaborate strategically, enhance platform adoption, and leverage data insights...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$117K - $156K *

Elevate strategic decision-making by managing integrated program plans, ensuring accurate portfolio data, and collaborating with cross-functional teams to drive continuous improvement in a fast-paced...

Cambridge, MARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $200K *

Unlock potential by leading a dynamic creative team to drive performance-focused video ads. Oversee the entire creative process, from concept to execution, ensuring data-driven decisions enhance custo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$120K - $150K *

Lead and scale a dynamic performance marketing strategy to enhance demand generation, optimize marketing initiatives, and drive revenue across multiple service units. Collaborate with teams to create...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Staffing

$109K - $173K *

Help us drive strategic project planning and AI adoption across teams, ensuring clear objectives and strong follow-up. Collaborate with cross-functional leaders to enhance visibility and efficiency in...

Ontario, CARemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Unlock potential by leading transformative ERP implementations and mentoring teams. Drive multi-phase projects, enhance client relationships, and ensure profitable outcomes through strategic analysis...

Louisville, KYRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$114K - $143K *

Drive operational excellence by leading complex PMO initiatives, enhancing governance, and implementing AI-driven methodologies. Collaborate cross-functionally to transform processes and elevate organ...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What does a Director of Operational Excellence do?question toggle

    A Director of Operational Excellence leads initiatives to improve organizational performance, processes, quality, and efficiency. The role often includes setting improvement strategy, tracking KPIs, guiding transformation projects, and helping teams adopt sustainable ways of working.

  • What qualifications are commonly required for Director of Operational Excellence jobs?question toggle

    Employers often seek a bachelor’s degree, extensive experience in operations or continuous improvement, and a record of leading cross-functional change. Lean or Six Sigma expertise, data analysis skills, and an advanced degree or relevant certification may be preferred.

  • How much do Director of Operational Excellence jobs pay?question toggle

    Compensation varies by industry, location, company size, and role scope. Ladders focuses on vetted professional jobs paying $100,000 or more, including senior operational excellence opportunities.

  • Which industries hire Directors of Operational Excellence?question toggle

    Manufacturing, healthcare, logistics, financial services, retail, technology, and other industries hire these leaders to improve processes, manage transformation, and strengthen operational performance.

  • What career paths can follow this role?question toggle

    Experienced Directors of Operational Excellence may advance to vice president of operations, chief operating officer, enterprise transformation executive, or other senior leadership positions.