Director of Operational Excellence Jobs

Discover Director of Operational Excellence opportunities on Ladders, where professionals can explore vetted jobs paying $100,000 or more. These senior leaders help organizations improve performance, streamline processes, and build a culture of continuous improvement. Roles span industries and may focus on enterprise transformation, quality, supply chain, manufacturing, healthcare, technology, or business operations.

What Does a Director of Operational Excellence Do?

A Director of Operational Excellence develops and leads initiatives that make an organization more effective, resilient, and customer-focused. Responsibilities often include identifying process gaps, setting improvement priorities, establishing performance measures, and partnering with executives and operational teams to deliver sustainable results. Depending on the employer, the role may oversee Lean, Six Sigma, change management, process design, or operational transformation programs.

Skills and Qualifications Employers Seek

Employers commonly look for strategic leadership, analytical problem-solving, change management, and the ability to influence across departments. Experience with continuous improvement methods such as Lean or Six Sigma, along with data analysis, project portfolio management, and KPI development, can be valuable. Many positions require a bachelor’s degree and substantial relevant experience; some prefer an advanced degree or professional certification.

Industries and Career Opportunities

Director of Operational Excellence roles are available in sectors where reliable, efficient processes are critical, including manufacturing, healthcare, financial services, logistics, retail, and technology. The scope varies: some directors lead improvement teams at a single site, while others shape operating models and transformation efforts across multiple business units or global organizations. Career paths may lead to vice president of operations, chief operating officer, or enterprise transformation leadership.

Find Director of Operational Excellence Jobs on Ladders

Use Ladders to explore vetted senior-level opportunities with salaries of $100,000 or more. Compare roles by industry, location, and scope, and look for positions that match your experience in operational strategy, process improvement, and executive leadership.

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$125K - $150K *

Drive your career with a leadership role overseeing marketing operations, guiding teams to enhance sales processes, optimize technology strategies, and deliver impactful data analysis for informed dec...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$159K - $257K *

Transform security posture by leading enterprise vulnerability management, prioritizing risks, and driving remediation efforts across diverse technology environments. Collaborate with teams to enhance...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $150K *

Lead the charge in executive support and strategic sales initiatives, managing schedules, communications, and events for the EVP of Global Client Services. Drive efficiency and stakeholder engagement...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$183K - $293K *

Champion a global Knowledge Management strategy to enhance customer experience, operational excellence, and digital transformation. Lead cross-functional teams to drive adoption of best practices and...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$155K - $210K *

Lead complex programs and strategic client engagements, driving technology transformation and sustainable business value. Act as a trusted adviser to C-level stakeholders, shaping program vision and e...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $140K *

Lead the charge in driving revenue growth and client retention by managing strategic relationships and optimizing transportation solutions for a diverse portfolio of enterprise clients. Your expertise...

Chicago, ILRemote

Today

  •   8 - 10 years exp.  •   Transportation

$175K - $200K *

Lead and evolve omnichannel strategy across diverse clients and brands, driving integrated customer experiences that align with business objectives while enhancing strategic capabilities in a dynamic...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$140K - $165K *

Elevate project management excellence by leading complex pharmaceutical marketing campaigns, mentoring teams, and ensuring strategic alignment with client objectives while driving operational success...

New York, NYRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Partner with us to lead a dynamic model audit team, enhancing financial modelling processes while driving strategic growth and innovation across projects, all while fostering a collaborative and high...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $140K *

Drive cost transparency and efficiency in manufacturing operations by analyzing product costs, collaborating with diverse teams, and supporting strategic initiatives to enhance profitability and busin...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$120K - $145K *

Lead a high-performing team to drive new business growth and customer acquisition. Shape strategic sales initiatives, build strong relationships, and optimize pipelines to achieve revenue goals across...

Florida, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$120K - $145K *

Drive new business growth by leading a high-performing team focused on customer acquisition and market expansion. Develop strategies, build relationships, and optimize sales processes to achieve measu...

Florida, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$140K - $150K *

Shape your career by managing clinical research studies, ensuring compliance with regulations, and leading cross-functional teams to achieve project milestones efficiently and effectively...

Boston, MARemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $185K *

Transform strategic sourcing for HR and Benefits, leading complex engagements and driving cost savings while ensuring high supplier performance and stakeholder satisfaction across diverse client needs...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Business Services

$180K - $220K *

Unlock potential by leading software systems management and optimization across a global portfolio. Collaborate with business and technology leaders to enhance operational efficiency, drive innovation...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$140K - $180K *

Unlock potential by leading client strategy and product initiatives, driving growth through market insights and cross-functional collaboration. Shape solutions that enhance client value and optimize H...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$165K - $215K *

Shape the future of value-based payments by leading product strategy, overseeing team development, and driving market innovations within a collaborative, cross-functional environment...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $150K *

Lead the charge in strategic sourcing and procurement excellence, partnering with business leaders to optimize categories, drive cost savings, and enhance supplier relationships while developing talen...

Virginia, USRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$88K - $95K *

Drive operational excellence by leading projects across teams, enhancing efficiency, managing stakeholders, and ensuring timely delivery. Collaborate within a dynamic environment dedicated to improvin...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$114K - $190K *

Drive the Integrated Operations Center, overseeing cybersecurity operations, fraud defense, and incident management. Lead cross-functional teams to enhance threat detection, operational resilience, an...

Lancaster, PARemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Unlock your potential to lead programmatic strategies, shape best practices, and empower teams to excel in the DSP landscape. Collaborate with stakeholders and transform our approach to digital advert...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$142K - $177K *

Lead the charge in transforming legacy applications into modern solutions. Drive software development excellence, foster team growth, and collaborate across departments to enhance customer experiences...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$101K - $154K *

Shape product strategy and commercialization efforts, ensuring alignment with market trends and customer needs. Drive product development, marketing initiatives, and cross-functional collaboration to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Transform client relationships by leading customer success strategies, driving utilization, and maximizing retention across enterprise health systems. Oversee a high-performing team to ensure client s...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Lead organizational change initiatives, driving employee adoption and engagement through strategic communication and training. Collaborate with leaders to assess readiness, mitigate resistance, and en...

Ohio, USRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What does a Director of Operational Excellence do?question toggle

    A Director of Operational Excellence leads initiatives to improve organizational performance, processes, quality, and efficiency. The role often includes setting improvement strategy, tracking KPIs, guiding transformation projects, and helping teams adopt sustainable ways of working.

  • What qualifications are commonly required for Director of Operational Excellence jobs?question toggle

    Employers often seek a bachelor’s degree, extensive experience in operations or continuous improvement, and a record of leading cross-functional change. Lean or Six Sigma expertise, data analysis skills, and an advanced degree or relevant certification may be preferred.

  • How much do Director of Operational Excellence jobs pay?question toggle

    Compensation varies by industry, location, company size, and role scope. Ladders focuses on vetted professional jobs paying $100,000 or more, including senior operational excellence opportunities.

  • Which industries hire Directors of Operational Excellence?question toggle

    Manufacturing, healthcare, logistics, financial services, retail, technology, and other industries hire these leaders to improve processes, manage transformation, and strengthen operational performance.

  • What career paths can follow this role?question toggle

    Experienced Directors of Operational Excellence may advance to vice president of operations, chief operating officer, enterprise transformation executive, or other senior leadership positions.