Director of Operational Excellence Jobs

Discover Director of Operational Excellence opportunities on Ladders, where professionals can explore vetted jobs paying $100,000 or more. These senior leaders help organizations improve performance, streamline processes, and build a culture of continuous improvement. Roles span industries and may focus on enterprise transformation, quality, supply chain, manufacturing, healthcare, technology, or business operations.

What Does a Director of Operational Excellence Do?

A Director of Operational Excellence develops and leads initiatives that make an organization more effective, resilient, and customer-focused. Responsibilities often include identifying process gaps, setting improvement priorities, establishing performance measures, and partnering with executives and operational teams to deliver sustainable results. Depending on the employer, the role may oversee Lean, Six Sigma, change management, process design, or operational transformation programs.

Skills and Qualifications Employers Seek

Employers commonly look for strategic leadership, analytical problem-solving, change management, and the ability to influence across departments. Experience with continuous improvement methods such as Lean or Six Sigma, along with data analysis, project portfolio management, and KPI development, can be valuable. Many positions require a bachelor’s degree and substantial relevant experience; some prefer an advanced degree or professional certification.

Industries and Career Opportunities

Director of Operational Excellence roles are available in sectors where reliable, efficient processes are critical, including manufacturing, healthcare, financial services, logistics, retail, and technology. The scope varies: some directors lead improvement teams at a single site, while others shape operating models and transformation efforts across multiple business units or global organizations. Career paths may lead to vice president of operations, chief operating officer, or enterprise transformation leadership.

Find Director of Operational Excellence Jobs on Ladders

Use Ladders to explore vetted senior-level opportunities with salaries of $100,000 or more. Compare roles by industry, location, and scope, and look for positions that match your experience in operational strategy, process improvement, and executive leadership.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
More
1
caret down

$70K - $105K *

Collaborate with cross-functional teams to drive project execution and operational excellence in medical communications. Leverage your project management skills to ensure timely delivery and high-qual...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$138K - $231K *

Lead revenue cycle operations for a multi-site Center of Excellence, driving performance improvements, managing budgets, and mentoring teams to enhance billing accuracy and cash collections while ensu...

Texas, USRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$225K - $285K *

Lead the implementation of global PLM/PDM systems, collaborating cross-functionally to enhance supply chain processes and support a Tier 1 ERP buildout, ensuring scalability and efficiency across inte...

San Francisco, CARemote

Today

  •   8 - 10 years exp.  •   Information Technology

$130K - $160K *

Drive operational excellence by leading a global team to deliver high-quality wellbeing programs. Collaborate with stakeholders to ensure effective execution, maintain standards, and enhance participa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $105K *

Shape impactful insights through analytics, driving data-informed decisions for healthcare clients. Collaborate with cross-functional teams to enhance marketing performance and audience understanding...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock your potential as a Technical Project Manager, driving software delivery timelines and ensuring seamless project execution with engineering and product teams. Foster strong stakeholder relation...

Toronto, ONRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Analyze and improve sales operations by collaborating with leadership to enhance forecasting, pipeline management, and overall performance. Establish scalable processes, transforming data into actiona...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $300K *

Champion strategic growth by partnering with executive leadership to drive operational excellence, enhance data integrity, and lead cross-functional initiatives that propel business expansion and prod...

Boston, MARemote

3 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$150K - $180K *

Accelerate growth by leveraging deep supply chain expertise to drive new business, optimize value chains, and deliver compelling ROI to executives. Collaborate cross-functionally to exceed sales targe...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Empower our team to build innovative security and governance solutions, shaping access management for both human and agent users. Lead a small, dynamic group as we define architectural foundations and...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Optimize the implementation of Epic Clinical EHR for State Healthcare Facilities, leading project planning, stakeholder engagement, and team coordination while ensuring quality, scope, and communicati...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$185K - $215K *

Champion AI integration across teams, driving transformative initiatives for measurable outcomes. Lead enterprise-wide AI adoption strategy, governance, and programs, influencing stakeholders to harne...

Toronto, ONRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $160K *

Transform the future of employee benefits by leading product management and IT operations. Drive strategic initiatives, oversee product development, and ensure compliance while collaborating with dive...

Clermont, FLRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Explore new opportunities as you drive growth in our driver network, working closely with cross-functional teams to strategize, implement, and scale initiatives that optimize onboarding and activation...

Ventura, CARemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$76K - $115K *

Join a team that's shaping the future of customer education through innovative instructional design. Leverage your expertise to create engaging learning experiences that empower users and drive succes...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$94K - $151K *

Shape the future of enterprise strategy by leading a diverse portfolio of programs and initiatives. Collaborate with cross-functional teams to drive measurable business value and ensure alignment with...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$155K - $170K *

Lead the charge in shaping enterprise business solutions through hands-on architecture and delivery in Microsoft Dynamics 365 Finance & Operations, focusing on integration, process optimization, and o...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Staffing

$100K - $120K *

Take ownership of diverse projects, leading cross-functional teams to ensure successful execution, from planning to closure. Drive innovation and efficiency while managing budgets and stakeholder comm...

Tennessee, USRemote

3 days ago

  •   Less than 5 years exp.  •   Transportation

$232K - $250K *

Lead the charge in enterprise technology strategy and governance. Spearhead innovative planning and oversight to enhance business outcomes, ensuring alignment with organizational goals and optimizing...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$90K - $110K *

Champion the optimization of business systems for Legal, Safety, and Environmental teams. Drive continuous improvement and support for Icertis and related applications, enhancing user experience and o...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$109K - $165K *

Build strong relationships at a leading IoT company, guiding enterprise customers through deployment and adoption of innovative solutions. Collaborate cross-functionally while driving customer success...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $166K *

Champion project execution and risk management in complex energy infrastructure, driving operational efficiency and digital innovation while collaborating with cross-functional teams to enhance projec...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$190K *

Transform the future of public safety as a Director of Product Management, leading a high-performing team to define and deliver innovative SaaS products. Collaborate across departments to drive produc...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $190K *

Accelerate progress at a leading Customer Success team, driving renewal outcomes and enhancing team effectiveness through innovative engagement strategies and AI-driven solutions for a diverse portfol...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Lead the evolution of our GTM Systems Architecture, enhancing Salesforce and its tech stack for AI-native workflows. Collaborate with cross-functional teams to build a trusted data foundation and driv...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What does a Director of Operational Excellence do?question toggle

    A Director of Operational Excellence leads initiatives to improve organizational performance, processes, quality, and efficiency. The role often includes setting improvement strategy, tracking KPIs, guiding transformation projects, and helping teams adopt sustainable ways of working.

  • What qualifications are commonly required for Director of Operational Excellence jobs?question toggle

    Employers often seek a bachelor’s degree, extensive experience in operations or continuous improvement, and a record of leading cross-functional change. Lean or Six Sigma expertise, data analysis skills, and an advanced degree or relevant certification may be preferred.

  • How much do Director of Operational Excellence jobs pay?question toggle

    Compensation varies by industry, location, company size, and role scope. Ladders focuses on vetted professional jobs paying $100,000 or more, including senior operational excellence opportunities.

  • Which industries hire Directors of Operational Excellence?question toggle

    Manufacturing, healthcare, logistics, financial services, retail, technology, and other industries hire these leaders to improve processes, manage transformation, and strengthen operational performance.

  • What career paths can follow this role?question toggle

    Experienced Directors of Operational Excellence may advance to vice president of operations, chief operating officer, enterprise transformation executive, or other senior leadership positions.