Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$110K - $130K *

Join a dynamic team as you lead Reader Operations, ensuring high-quality imaging services. Drive strategic initiatives, enhance operational performance, and foster team collaboration to meet corporate...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$263K - $318K *

Transform your career by leading automation operations that enhance scientific workflows. Oversee multidisciplinary teams to build and optimize integrated platforms, ensuring reliability and scalabili...

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$350K - $400K *

Transform the landscape of addiction treatment by overseeing clinical services, guiding medical providers, and ensuring compliance with regulations while enhancing patient recovery efforts and educati...

4 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Transform nursing operations by leading staff, managing budgets, and ensuring compliance with standards. Drive quality improvement initiatives and foster a culture of safety and excellence in patient...

Today

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Help us drive operational excellence in clinical settings by overseeing key functions and collaborating with healthcare professionals to enhance patient care and efficiency. Your leadership will shape...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Champion risk management initiatives to ensure a safe environment for patients, staff, and visitors while ensuring compliance with regulatory standards and promoting a culture of safety and continuous...

4 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$75K - $90K *

Join us in overseeing clinic operations, ensuring quality patient care, and leading a dedicated team. Collaborate with leadership to enhance financial performance while fostering a supportive environm...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $92K *

Transform clinical operations by leading, training, and motivating staff to deliver exceptional patient care while ensuring compliance and efficiency. Collaborate across departments to optimize perfor...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$215K - $408K *

Join a team that's dedicated to enhancing medical management and quality improvement. Collaborate with clinical teams to optimize patient care, support performance initiatives, and drive effective uti...

Georgia, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$215K - $408K *

Lead the charge in enhancing medical management and quality improvement. Drive utilization review, collaborate with providers, and implement performance initiatives to optimize care quality and cost-e...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Pioneer exceptional customer service operations by leading high-performing teams, optimizing processes, and driving innovation. Ensure compliance and enhance beneficiary engagement through strategic o...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $110K *

Transform patient care by leading an outpatient clinic, fostering relationships, and driving growth. This role combines management with community engagement, ensuring exceptional service and continuou...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Elevate your career by providing leadership and operational oversight in a dynamic inpatient care environment. Drive quality service, patient safety, and team excellence while achieving departmental a...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $110K *

Champion exceptional patient care as an outpatient center manager, leading a dedicated team of physical therapists. Drive community partnerships and enhance service delivery while fostering profession...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $110K *

Join a team that's dedicated to enhancing patient care as an outpatient center manager. Oversee a skilled therapy team, foster community partnerships, and drive optimal outcomes while promoting profes...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $110K *

Manage and lead a dedicated therapy team to deliver exceptional patient care, oversee operations, and foster community relationships while promoting wellness and functionality in a supportive outpatie...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $110K *

Champion clinic operations by leading a dynamic team, fostering patient relationships, and driving growth through community engagement while ensuring exceptional care in a thriving outpatient setting...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $110K *

Transform patient care as you lead a dynamic outpatient therapy team, ensuring exceptional rehabilitation services while fostering community partnerships and professional growth...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $110K *

Lead the development and management of an outpatient center, fostering community partnerships and optimizing patient outcomes while expanding a skilled team of physical therapists and assistants...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $110K *

Empower patient care as a Center Manager/Physical Therapist, leading a new outpatient facility. Drive excellence in orthopedic treatment, foster community partnerships, and cultivate a talented team w...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $110K *

Grow your career with a leadership role in outpatient therapy, overseeing a dedicated team while enhancing patient care and community partnerships. Drive optimal outcomes and foster a collaborative en...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $120K *

Lead and enhance patient care as an outpatient clinic director, overseeing a dedicated team of physical therapists. Drive community partnerships and optimize rehabilitation services to promote patient...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $120K *

Lead the charge in delivering exceptional patient care as an outpatient clinic director. Oversee a dedicated team, enhance community partnerships, and drive optimal outcomes while fostering a supporti...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $120K *

Lead and inspire a dynamic outpatient therapy team, enhancing patient care and outcomes. Oversee operations, foster physician relationships, and drive community engagement while advancing your career...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $120K *

Take ownership of a dynamic outpatient center, leading a team to deliver exceptional orthopedic care while fostering community partnerships and enhancing patient outcomes through innovative rehabilita...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.