Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$162K - $243K *

Join a team that's dedicated to advancing clinical trials through strategic oversight and collaboration. Lead project management efforts globally, ensuring quality, cost, and timeline objectives are m...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Transform your career by leading a dynamic behavioral health center, overseeing operations, and ensuring quality care. Drive clinical excellence and financial performance while making a meaningful imp...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Drive impactful change as you lead operations at a new behavioral health center, ensuring quality care and compliance while managing a dedicated team. Your expertise will shape services for individual...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead a dynamic team in delivering high-quality clinical services while overseeing operational efficiency, ensuring compliance, and fostering community relationships to enhance patient care and program...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading clinical reimbursement strategies across skilled nursing facilities, ensuring compliance and optimal performance through collaboration with multidisciplinary teams to enhan...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $250K *

Join a team that's dedicated to providing compassionate psychiatric care for children and adolescents. Lead clinical quality improvements, supervise staff, and ensure compliance with regulations while...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$60K - $132K *

Champion operational excellence by coordinating teams to enhance efficiency, manage resources, and drive process improvements. Collaborate across functions to meet business objectives and foster a cul...

Texas, USRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$54K - $119K *

Lead the charge in optimizing operational efficiency by coordinating cross-functional teams, managing resources, and driving process improvements to enhance service delivery and achieve business objec...

Kentucky, USRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Elevate inpatient nursing services by fostering collaboration, driving strategic initiatives, and enhancing operational efficiency. Lead projects, manage data, and support nursing leadership to achiev...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $211K *

Drive strategic and operational leadership for ambulatory services across multiple specialties, ensuring quality, safety, and financial performance while fostering collaboration and accountability amo...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$92K - $124K *

Lead clinical operations to ensure high-quality patient care and staff support. Collaborate with teams to create a safe, therapeutic environment while overseeing hiring, training, and compliance for o...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$295K - $463K *

Empower patient care by leading a multidisciplinary team in adult and geriatric inpatient psychiatry. This role combines medical leadership with clinical practice, ensuring high-quality psychiatric se...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$165K - $180K *

Join our team to oversee the execution and management of regional clinical trials, driving operational excellence while collaborating across functions. Bring your expertise to lead clinical operations...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $180K *

Oversee and optimize US regional clinical trials, ensuring execution and compliance. Collaborate with cross-functional teams and manage vendor relationships while driving process improvements in a fas...

Houston, TXRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Oversee operations management across multiple health centers, driving strategic initiatives and enhancing client satisfaction. Lead and mentor teams while implementing innovative performance standards...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Unlock potential by leading operations across multiple health centers, enhancing client satisfaction and performance. Drive strategic initiatives, manage complex relationships, and mentor leadership t...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$248K - $461K *

Drive comprehensive translational strategies in neurodegeneration, overseeing biomarker development, clinical trial design, and operational execution to advance innovative therapies and ensure robust...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion organizational growth by leading strategic initiatives, optimizing community partnerships, and enhancing data governance to support sustainable funding and impactful health outcomes for the C...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$90K - $194K *

Join a team that's dedicated to advancing community health initiatives. Lead program operations, manage partnerships, and ensure compliance while driving impactful projects that align with strategic o...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Join a dynamic team to oversee operations across medical offices, ensuring compliance, managing projects, and enhancing processes. Lead staff development and maintain operational excellence while fost...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $100K *

Champion clinic operational excellence by leading teams, overseeing daily functions, and driving patient experience in a fast-paced, patient-centric environment, while ensuring compliance and optimizi...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Join a team that champions operational excellence and patient-centered care while leading a dedicated clinic team. Drive high engagement, optimize workflows, and ensure compliance, all while enhancing...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$117K - $164K *

Lead the charge in executing strategic projects across multiple business units, ensuring operational excellence and fostering team collaboration. Drive process optimization and champion project manage...

2 days ago

  •   Less than 5 years exp.  •   Media

$160K - $200K *

Empower healthcare innovation by leading clinical applications, ensuring systems are reliable and user-friendly. Collaborate with teams to enhance care delivery, optimize workflows, and drive strategi...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$96K - $128K *

Shape the future of wound care management by leading strategic growth and operational excellence in our Wound Care Program. Oversee clinical functions, financial management, and community education wh...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.