Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$110K - $130K *

Drive efficient order management and logistics operations, ensuring compliance with pharmaceutical regulations while collaborating with internal teams and 3PL partners to optimize product flow and per...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Join us in providing strategic financial leadership to enhance planning, forecasting, and performance management. Collaborate with executives to translate business strategies into actionable financial...

Maitland, FLRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$139K - $280K *

Lead a dynamic team in driving commercial success across Neuroscience and Cardiovascular portfolios. Collaborate with cross-functional partners to enhance customer engagement and execute strategic bus...

Florida, USRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$187K - $234K *

Drive the future of patient care by leading product strategy across Virtual Pharmacy, Patient App, and Partnerships. Shape high-impact initiatives, mentor teams, and enhance operational excellence thr...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$167K - $300K *

Unlock your potential by leading regional oncology thought leader engagement and advocacy strategies. Collaborate with cross-functional teams to shape brand strategy and launch planning for innovative...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$133K - $237K *

Contribute to patient safety by overseeing medical product surveillance, analyzing data, and ensuring compliance with regulations. Collaborate on risk management and support clinical studies to enhanc...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$112K - $193K *

Innovate the future of AI-driven revenue cycle products, leading strategy, commercialization, and product delivery. Collaborate across teams to drive adoption and revenue growth while navigating compl...

Minneapolis, MNRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Join a team that's redefining audit practices by leading the transition to an agentic operating model. Collaborate across functions to innovate audit methodologies and drive transformation for clients...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$131K - $303K *

Join a team that's at the forefront of healthcare analytics, driving innovation and strategy. You will support financial stewardship, operational excellence, and executive communications in a high-vis...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$76K - $199K *

Help us drive sales and build relationships in the Neuroscience sector by promoting innovative migraine therapies. Engage with healthcare professionals to implement strategic business plans and enhanc...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Accelerate customer journey operations by driving scalable processes and systems. Collaborate cross-functionally to enhance customer success, technical support, and partner engagement, ensuring effici...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $192K *

Drive the expansion of revenue cycle workflow products, collaborating across teams to define business requirements, develop product roadmaps, and ensure effective delivery using Agile methodologies fo...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Empower growth by building relationships with physicians and identifying new opportunities. Collaborate with leadership to enhance market share and drive initiatives that increase procedure volume in...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$259K - $350K *

Redefine the future of cybersecurity by leading product strategy for a cutting-edge Managed Detection & Response portfolio, driving innovation and customer success while managing a high-performing tea...

California, USRemote

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$100K - $170K *

Transform early-career recruiting by building relationships with universities, sourcing top talent, and enhancing campus strategies to attract exceptional candidates for technical roles...

New York, NYRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's redefining inpatient coding operations, ensuring quality and compliance while optimizing workflows. Lead a dedicated team to enhance documentation practices and support financial he...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$124K - $207K *

Join a team that's transforming risk data into actionable insights. Lead analytics and decision support initiatives, manage delivery roadmaps, and enhance team capabilities to drive effective risk man...

Philadelphia, PARemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a team that's redefining customer success by leveraging AI to enhance the post-sale journey. Lead and scale a dynamic team while driving retention and expansion for enterprise clients in a fast-p...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Unlock potential by managing system design, build, and support for applications, ensuring optimal functionality and user satisfaction while collaborating across teams to enhance workflows and resolve...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $140K *

Unlock potential by owning executive-level client relationships, driving integrated strategies, and leading action-oriented touchpoints that translate insights into measurable outcomes while championi...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Media

$104K - $176K *

Lead operational excellence within the Customer Success teams, driving impactful programs that enhance performance and efficiency while fostering collaboration across cross-functional teams in a dynam...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Empower your career by driving EHR operations and support. Collaborate with teams to enhance MyEvolv workflows, troubleshoot issues, and optimize user experience, ensuring efficient system performance...

New York, NYRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Empower global regulatory strategies and drive business growth while leading multidisciplinary collaborations in a fast-paced environment. Leverage your expertise to guide clients through complex regu...

Boston, MARemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Lead the charge in analytical development, overseeing drug substance and product strategies. Collaborate across teams to ensure compliance and performance, while mentoring a high-performing analytical...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Pioneer complex ERP implementations by leading diverse teams, managing risks, and aligning project outcomes with client objectives while ensuring timely, on-budget delivery across multiple projects...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.