Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$97K - $193K *

Transform clinical research by ensuring high-quality study execution and compliance. Collaborate with sites and teams to drive data integrity and patient safety, influencing successful outcomes throug...

Texas, USRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$174K - $261K *

Lead the charge in transforming enterprise technology strategies by coaching a specialized sales team. Drive complex sales cycles and build executive relationships to unlock business value through inn...

Remote, ORRemote

6 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$140K - $160K *

Lead our initiatives in designing and constructing innovative water and carbon capture facilities globally. Collaborate across teams to ensure project success within budget and timeline while promotin...

California, USRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $120K *

Shape the future of executive recruitment by leading strategic sourcing, engaging high-level candidates, and collaborating with a dedicated team to uncover top talent. This role offers growth opportun...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $240K *

Shape the future of enterprise security by leading vulnerability management initiatives. Drive strategy, execution, and collaboration across teams to enhance risk reduction and improve security outcom...

Charlotte, NCRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$115K - $175K *

Lead the creative program management efforts, ensuring timely delivery of high-quality projects across various marketing initiatives. Drive process improvements and foster collaboration within a dynam...

Seattle, WARemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Shape the future of patient services by ensuring timely delivery of features and integrations. Collaborate across teams to enhance operational efficiency in a compliance-heavy environment, driving inn...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$164K - $247K *

Join a dynamic team to lead central monitoring efforts in clinical trials, driving data-driven insights and risk management strategies. Collaborate across functions to enhance monitoring efficiency an...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$128K - $254K *

Oversee and manage large-scale, multi-national projects, ensuring successful delivery through direct team leadership and cross-functional collaboration, while maintaining high quality and financial pe...

RemoteRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $140K *

Reimagine client success by managing relationships and ensuring seamless communication across teams. Drive operational excellence and enhance client satisfaction through proactive updates, coordinatio...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$220K - $290K *

Accelerate the development of autonomous systems by leading systems engineering strategies, aligning cross-functional teams, and ensuring rigorous safety and performance standards throughout the produ...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$85K - $120K *

Transform market dynamics by building strategic relationships with healthcare provider networks. Drive referral growth and partnership initiatives while collaborating with cross-functional teams to en...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$204K - $274K *

Champion the U.S. Biologics Regulatory CMC team by providing strategic leadership, ensuring timely regulatory submissions, and fostering collaboration among global stakeholders to drive innovative bio...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Drive reputation management and consumer insights initiatives, enhancing brand trust and informing strategic decisions. Collaborate across teams to analyze data, identify trends, and improve consumer...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading a high-performing team that shapes the future of our Association, guiding strategic initiatives to enhance member value, organizational growth, and community impact through...

Forest Hill, MDRemote

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Drive operational excellence by developing and maintaining standards, ensuring consistency across markets, and collaborating with cross-functional teams to enhance processes and documentation for opti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Transform state performance by driving growth and profitability through strategic management of pricing, underwriting, and market analysis. Collaborate across departments to enhance compliance and eff...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$188K - $235K *

Unlock potential by shaping and driving the People Systems roadmap, translating business needs into scalable processes, and managing technology vendors to enhance the employee lifecycle through innova...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $231K *

Lead a team to optimize analytics capabilities, drive forecasting, and deliver AI-driven insights that enhance sales performance and support strategic business goals in a collaborative environment...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$91K - $163K *

Lead transformative credit operations by optimizing workflows, enhancing AI integration, and driving process excellence. Collaborate across functions to manage multi-million-dollar portfolios and ment...

Draper, UTRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $170K *

Shape the future of healthcare technology by leveraging your expertise to drive sales success. Collaborate with cross-functional teams to deliver tailored solutions, engage customers, and enhance prod...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by driving partnerships within health systems, building strategic relationships, and creating impactful ecosystems that accelerate product adoption and streamline sales cycles, while...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Transform the IT landscape by leading a dynamic team of product managers and analysts, driving innovation and strategic alignment to enhance enterprise value and ensure compliance while fostering coll...

Atlanta, GARemote

Today

  •   8 - 10 years exp.  •   Healthcare

$112K - $193K *

Champion financial leadership for shared services in a dynamic environment, overseeing forecasting, budgeting, and reporting while driving cost management and accountability across a complex organizat...

Eden Prairie, MNRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $95K *

Transform client relationships by leading strategic projects, ensuring quality and alignment across teams. Collaborate with stakeholders to drive success and meet client expectations while fostering g...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.