Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Medical Director, Vascular Surgery - Remote
$248K - $373K *
Join a team that's shaping the future of healthcare through innovative claims review. Lead quality assurance for medical services, engage with providers, and influence policy development, while enjoyi...
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Principal Client Success Manager
$110K - $130K *
Unlock potential by managing complex relationships with multi-hospital systems, guiding clients through intricate reimbursement processes, and influencing strategies that drive partnerships and operat...
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Sr. Manager, Central Monitoring, Data Analysis
$120K - $145K *
Drive impactful data analysis and risk management for global clinical trials, interpreting complex data to identify trends and risks. Lead cross-functional teams in enhancing study quality and patient...
5 days ago
$180K - $210K *
Elevate creative excellence by leading a multidisciplinary team, setting vision and quality standards, and driving impactful brand strategies across diverse channels in a dynamic healthcare environmen...
2 weeks ago
Clinical Documentation Integrity Supervisor
$110K - $159K *
Inspire excellence in clinical documentation by leading a team of specialists, ensuring quality assurance, and fostering professional development. Collaborate with stakeholders to enhance operational...
1 week ago
Clinical Documentation Integrity Supervisor
$110K - $159K *
Lead the charge in enhancing clinical documentation integrity by supervising staff, conducting quality reviews, and fostering professional development. Collaborate with teams to implement effective st...
2 weeks ago
Associate Director, Thought Leader Liaison, Oncology - Central
$157K - $256K *
Champion strategic engagements with oncology thought leaders to enhance insights and drive initiatives for our Solid Tumor portfolio, focusing on collaboration across teams and executing regional stra...
1 week ago
$210K - $225K *
Pioneer innovative research strategies to enhance clinical outcomes and drive impactful insights through collaboration across teams, while establishing a robust research infrastructure and publication...
4 weeks ago
$87K - $157K *
Elevate your career by leading strategic programs and large-scale projects. Drive cross-functional collaboration, manage complex integrations, and deliver impactful executive communications to achieve...
Reposted today
Strategy and Operations Associate, GTM
$100K - $110K *
Drive strategic GTM initiatives and optimize operations across teams. Collaborate with leadership to enhance revenue processes, leveraging AI tools and data insights to ensure alignment and execution...
1 week ago
SENIOR HEALTH SYSTEMS PROJECT MANAGER
$120K - $183K *
Empower your career by leading large-scale health system projects, managing complex initiatives, and guiding teams to achieve strategic goals. Collaborate with senior leaders to drive impactful outcom...
3 weeks ago
Revenue Operations & Clean Claim Manager
$95K - $115K *
Drive revenue operations excellence by leading clean-claim workflows, overseeing claim accuracy, and enhancing cross-functional collaboration. Partner with various departments to ensure timely billing...
3 weeks ago
Operations Support & Strategy Manager
$109K - $144K *
Join a dynamic team to drive operational excellence and process improvements in healthcare. Lead complex initiatives, influence strategy, and enhance care delivery while collaborating across multiple...
Yesterday
$80K - $95K *
Manage and optimize the administrative and financial operations of the Sponsored Programs division, enhancing funding levels and proposal output while ensuring compliance with policies and effective r...
3 weeks ago
Senior Vice President, Delivery - Denials Resolution and Payment Compliance
$210K - $250K *
Shape the future of healthcare delivery by leading operations in denials resolution and payment compliance. Drive performance, quality, and financial outcomes while building a high-performing team and...
4 days ago
$110K - $130K *
Oversee the planning and execution of clinical trials, ensuring compliance and data integrity while collaborating with cross-functional teams to drive innovative treatments and therapies forward...
3 weeks ago
Legal Operations & Compliance Lead
$110K - $130K *
Pioneer impactful legal operations and compliance practices that enhance team efficiency. Oversee systems, processes, and compliance initiatives that support a dynamic, fast-growing global business en...
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$110K - $130K *
Join a dynamic team to innovate and deliver high-quality software solutions. Collaborate in an Agile environment, leveraging modern technologies to enhance product functionality and customer satisfact...
2 weeks ago
Client Director- US West (Professional Services Sales)
$132K - $199K *
Champion client success by driving Professional Services sales and revenue generation. Collaborate across North America to enhance client relationships and maximize value through effective solution im...
1 week ago
$110K - $130K *
Join a team that's defining and driving enterprise data governance for a federal agency. Collaborate with stakeholders to establish data quality frameworks and compliance protocols, ensuring best prac...
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$125K - $150K *
Pioneer in radiology innovation by enhancing clinical value and technology. Join a forward-thinking team that prioritizes high-quality patient care while driving improvements in service and operationa...
Reposted 2 weeks ago
Account Director - Medical Communications
$130K - $140K *
Join a team that's dedicated to driving client success in oncology. As a key leader, you'll manage relationships, oversee project delivery, and foster growth across a diverse portfolio, ensuring high...
4 days ago
$90K - $110K *
Join a team that's redefining change management in healthcare. Support the adoption of innovative informatics solutions, ensuring seamless transitions and user readiness across the Veterans Health Adm...
3 weeks ago
Manager, Sponsored Programs (Post Award)
$80K - $95K *
Unlock potential by leading the Sponsored Programs division to enhance funding levels and proposal output. Oversee financial management, develop policies, and ensure compliance while fostering collabo...
Reposted 3 days ago
$80K - $100K *
Transform data into actionable insights, empowering operational leaders to enhance client performance and uncover strategic opportunities across diverse datasets and analytical challenges...
4 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.