Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$132K - $232K *

Redefine career mobility strategies by integrating talent marketplace capabilities, enabling associates to explore growth opportunities through data-informed solutions and collaborative practices acro...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Business Services

$120K - $150K *

Empower a healthcare association by leading strategic initiatives, fostering partnerships, and driving revenue growth. Collaborate with stakeholders to enhance program excellence and ensure effective...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$90K - $130K *

Engage teams in revenue cycle operations to drive performance and efficiency. Lead strategic initiatives while managing day-to-day operations, ensuring optimal service delivery and financial outcomes...

Chicago, ILRemote

4 days ago

  •   5 - 7 years exp.  •   Business Services

$120K - $150K *

Unlock new opportunities by building strategic partnerships with academic institutions to enhance research in neurology, psychiatry, and sleep. Collaborate with principal investigators to drive adopti...

Boston, MARemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in optimizing healthcare processes for the Veterans Health Administration, enhancing business and clinical operations. Collaborate with stakeholders to redesign workflows, address chal...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$145K - $185K *

Join a dynamic team as a Senior Marketing Analytics Manager, driving marketing performance measurement and insights. Collaborate cross-functionally to build impactful reporting and attribution models...

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1 week ago

  •   5 - 7 years exp.  •   Information Technology

$162K - $224K *

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1 week ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $150K *

Elevate support operations by leading AI transformation initiatives, enhancing customer experience and operational efficiency through strategic ServiceNow platform management and innovative workflow r...

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1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $120K *

Elevate healthcare technology as a senior analyst, optimizing complex Epic applications. Collaborate with stakeholders to enhance operational efficiencies and support application users, while mentorin...

Miami, FLRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead global clinical studies across diverse therapeutic areas, ensuring operational excellence and client satisfaction through effective project management and team leadership...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $85K *

Optimize partnerships with healthcare entities to enhance cancer care access and outcomes, while driving strategic initiatives and influencing policy through collaborative efforts across the cancer ca...

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Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Shape the future of healthcare by driving customer success and engagement. As a key advisor, you'll enhance client relationships, advocate for their needs, and identify growth opportunities within a d...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $135K *

Unlock potential by leading global oncology clinical trials, driving project execution, managing timelines, and collaborating across teams to deliver innovative therapies for patients worldwide in a d...

Indiana, USRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$120K - $135K *

Join a team that's dedicated to advancing cancer therapies by leading global oncology clinical trials, managing cross-functional study teams, and ensuring high standards of study execution and complia...

Tennessee, USRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $135K *

Lead the charge in advancing oncology research by managing global clinical trials. Utilize your expertise to ensure seamless operation, compliance, and timely delivery across diverse oncology studies...

Minnesota, USRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $135K *

Drive global oncology clinical trials by managing operational execution and ensuring compliance with timelines and regulations. Collaborate with cross-functional teams to advance cancer research and d...

Oklahoma, USRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$148K - $175K *

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Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Drive impactful strategies by leveraging research and insights to advance government health opportunities. Collaborate with leaders to enhance competitive positioning and secure meaningful work that b...

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1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$202K - $253K *

Elevate your leadership as you drive engineering excellence, overseeing multiple squads from prototype to production. Shape the roadmap, empower teams, and ensure quality delivery while staying techni...

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Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Champion integrated project management for complex pharmaceutical advertising, leading cross-functional teams to ensure timely delivery within scope and budget while mentoring junior staff and enhanci...

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5 days ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $190K *

Transform data into actionable insights by leading a team of data scientists and analysts. Drive advanced analytics initiatives, foster collaboration with stakeholders, and ensure high-quality deliver...

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4 days ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $291K *

Shape the future of AI by leading enterprise-level initiatives across multiple business units, driving investment decisions, and mentoring teams to achieve transformative results with cutting-edge tec...

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Reposted today

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Lead strategic growth initiatives across a defined region, mentoring a high-performing team to exceed goals while fostering strong provider relationships and ensuring alignment with service delivery...

Mckinney, TXRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Elevate your career by joining a dynamic team focused on transforming corporate learning. As a senior leader, you'll drive strategic initiatives, engage with top executives, and shape the future of wo...

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6 days ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Shape the future of discovery operations by leveraging your legal expertise and leadership skills to enhance service delivery and team performance, ensuring top-quality results and efficient workflows...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.