Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Director of Strategic Health System Partnerships
$273K - $381K *
Drive enterprise growth by building strategic partnerships with major health systems. Lead complex sales initiatives, collaborate across teams, and develop innovative solutions to enhance market share...
1 week ago
$150K - $185K *
Shape strategic success for key accounts by leading market access initiatives, collaborating with cross-functional teams, and driving growth through innovative solutions and insights in the managed ma...
2 weeks ago
Lead Director, Medical Benefit Portfolio Product Management (Central Region)
$100K - $231K *
Unlock market potential by leading product strategy and execution for the Central Region. Drive portfolio performance, align cross-functional teams, and enhance customer value through innovative healt...
Reposted 4 days ago
Senior Marketing Manager, HCP Non-Personal Promotions, Prostate Cancer
$149K - $202K *
Join a team that's shaping innovative HCP non-personal promotional strategies for prostate cancer. Lead impactful campaigns, collaborate with cross-functional teams, and drive insights for improved pa...
Reposted 1 week ago
$88K - $115K *
Unlock your potential in a pivotal integration role, ensuring customer success through seamless technical setups, collaboration across teams, and enhancement of integration performance for optimal sat...
4 weeks ago
New Product Planning Associate Director - Biopharma
$162K - $203K *
Shape the future of biopharma by leading commercial strategies for CNS pipeline programs, integrating R&D insights, and guiding investment decisions to ensure clinical and market success across multip...
3 weeks ago
$145K - $218K *
Join us in leading global Phase I–IV clinical trials, ensuring operational excellence and compliance. Oversee strategy, manage vendors, and collaborate with cross-functional teams to drive successful...
3 weeks ago
Senior Compensation Consultant
$110K - $130K *
Lead complex compensation initiatives, ensuring equitable pay programs while managing projects. Serve as a subject matter expert in various compensation areas and collaborate with teams to enhance org...
Reposted 3 days ago
MRD Clinical Account Executive, North Houston
$95K - $155K *
Transform healthcare by driving the adoption of innovative MRD testing services. Engage with key stakeholders, develop strategic partnerships, and enhance client relationships to promote cutting-edge...
Today
$104K - $130K *
Join a team that's driving project success in mission-critical environments. As a Project Manager, you'll oversee design and construction phases, manage stakeholder relations, and ensure project profi...
3 weeks ago
Director, AI Transformation, Cvent Consulting
$150K - $180K *
Lead the charge in AI transformation for Fortune 500 clients, shaping solutions that drive measurable business outcomes. Collaborate with cross-functional teams to deliver high-quality engagements and...
3 weeks ago
Strategic Partnerships Director
$125K - $150K *
Lead the charge in forging strategic partnerships with financial institutions, driving growth through innovative market strategies, complex negotiations, and cross-functional collaboration to enhance...
2 weeks ago
Senior Marketing Operations Manager
$120K - $145K *
Drive the evolution of the Marketing PMO, enhancing planning, governance, and execution across functions. Lead strategic programs, optimize workflows, and establish metrics to ensure predictable outco...
1 week ago
$165K - $180K *
Transform your career by driving new customer acquisition in healthcare. Leverage your expertise to build C-suite relationships and lead complex sales processes, contributing to the growth of a dynami...
1 week ago
Manager, Strategic Client Solutions
$100K - $120K *
Accelerate client relationships by managing strategic accounts, driving revenue growth, and expanding service lines. Collaborate with internal teams to ensure client satisfaction and deliver tailored...
Today
Director, Integrated Marketing
$130K - $160K *
Join a dynamic team to drive integrated marketing strategies that enhance brand visibility and support business growth through innovative campaigns, digital activation, and thought leadership across m...
1 week ago
RCM Regional Sales Manager, Strategic
$110K - $130K *
Accelerate progress at the forefront of healthcare sales by driving revenue growth and expanding strategic partnerships in the RCM sector. Lead comprehensive sales strategies to engage large clients a...
2 weeks ago
Director Of Business Development / Long-Term Care Pharmacy Sales
$110K - $120K *
Accelerate growth in the Assisted Living sector by leading business development initiatives, collaborating with cross-functional teams, and driving customer acquisition strategies to meet revenue obje...
1 week ago
Director of Cyber Security Operations
$208K - $235K *
Join an enterprise-scale cybersecurity team leading operations, incident response, and risk management across cloud and hybrid infrastructures. This role drives innovation in security architecture whi...
4 weeks ago
$105K - $125K *
Lead technology operations for global teams, optimizing systems and support. Collaborate on strategic AI solutions, ensuring compliance and enhancing workflows. Drive efficiency and innovation in a dy...
6 days ago
Director, Strategic Growth & Institutional Funding
$110K - $130K *
Transform K-12 education by driving strategic growth through grant writing and funding acquisition. Collaborate with K-12 leaders to identify opportunities and unlock essential resources for education...
4 weeks ago
Regional Patient Access Manager - Long Term Care, Mid South
$151K - $206K *
Empower patient access by providing education and support to healthcare professionals, ensuring effective communication with pharmacies and payers, and optimizing distribution networks for timely trea...
3 days ago
$100K - $120K *
Join an aviation leadership team to oversee operations in the Northeast region. Ensure compliance, manage safety training, and support flight personnel, while fostering relationships and driving excel...
Reposted 4 weeks ago
$120K - $180K *
Shape the future of neuroscience by leveraging AI to enhance research methodologies. Collaborate with experts to define benchmarks, analyze data, and ensure AI agents meet rigorous scientific standard...
1 week ago
$145K - $160K *
Lead the charge in transforming member support by defining strategy, enhancing team performance, and integrating AI solutions. Drive operational excellence while fostering a culture of empathy and acc...
Yesterday
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.