Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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1
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$76K - $199K *

Drive sales and foster relationships in the healthcare sector by engaging customers through innovative strategies and effective communication, while leveraging analytical skills and product knowledge...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Lead the charge in enhancing member care as you coach and develop clinical teams, oversee daily operations, and ensure compliance with regulatory standards while driving quality improvements and opera...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $87K *

Lead the charge in strategic oversight and operational direction across multiple service areas, ensuring compliance and quality improvement while fostering a culture of person-centered care and team d...

Danvers, MARemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $225K *

Optimize logistics operations by managing product distribution and temperature-controlled shipments. Collaborate with cross-functional teams to enhance supply chain efficiency and ensure compliance in...

Boston, MARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $101K *

Lead the charge in executing client transition projects, managing onboarding and account expansions. Collaborate with teams to ensure seamless experiences while overseeing budgets, timelines, and stak...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$153K - $268K *

Empower your career by leading bio sample operations across clinical studies. Oversee end-to-end processes, ensuring compliance and quality while collaborating with cross-functional teams and external...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$195K - $225K *

Shape technology strategy and drive innovation within a dynamic organization, collaborating closely with leadership to enhance business value, build partnerships, and oversee digital transformation ef...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Elevate your career by leading the strategy and delivery of a robust Salesforce ecosystem, driving business impact through innovative solutions and team development in a dynamic, global environment...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $200K *

Drive the growth of Data Science and AI initiatives across diverse sectors, focusing on strategic industries. Lead business development, advisory roles, and solution creation to enhance client engagem...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$181K - $261K *

Lead transformation initiatives by aligning digital innovation with strategic goals, fostering external partnerships, and driving opportunity assessment for impactful business solutions...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $122K *

Unlock potential by leading a dynamic accounting team, managing full-cycle accounting processes, ensuring compliance, and driving process improvements in a fast-paced environment. Collaborate with fin...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock compensation strategies by partnering with teams to analyze, model, and deliver data-driven solutions. Drive benchmarking, job architecture, and annual comp cycles to ensure equitable pay pract...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$60K - $132K *

Elevate operational excellence by coordinating cross-functional teams, optimizing resource utilization, and driving process improvements to enhance efficiency and customer satisfaction while achieving...

Florida, USRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $202K *

Drive product operations excellence by leading cross-functional teams, enhancing AI integration, and optimizing UX design to ensure a seamless product development lifecycle that empowers rapid, high-q...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Transform the finance function by leading operations, capital strategy, and team building in a fast-growing software company. Collaborate with leadership to drive accountability and operational effici...

New York, NYRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$248K - $373K *

Drive the charge in clinical excellence by leading coverage determinations and collaborating with multidisciplinary teams to ensure quality medical care and cost-effectiveness for members across Enter...

Phoenix, AZRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Elevate your career by managing comprehensive HR operations, fostering employee relations, and ensuring compliance. Collaborate across teams while driving strategic initiatives and providing hands-on...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$120K - $145K *

Pioneer innovative finance systems to enhance automation and reporting. Lead the integration of AI and controls in a fast-growing mental health company, collaborating across teams to ensure scalable f...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Optimize your career by leading insights-driven strategies that shape brand decisions. Collaborate across functions to deliver actionable market research and analysis, driving impactful outcomes in a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead strategic initiatives in oncology nursing, optimizing field operations and education. Collaborate across functions to enhance performance and ensure compliance, driving impactful execution of por...

Boston, MARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Unlock potential by leading strategic initiatives across oncology franchises. Collaborate with cross-functional teams to enhance field operations, optimize resources, and drive effective nursing educa...

Denver, CORemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Unlock strategic potential by leading oncology nursing initiatives across multiple franchises. Collaborate with cross-functional teams to enhance field execution, optimize operations, and drive impact...

Atlanta, GARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in developing and executing oncology nursing strategies across multiple franchises, ensuring alignment and resource optimization for high-impact field performance in a dynamic, cross-f...

Dallas, TXRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $155K *

Champion the clinical implementation of diagnostic solutions, guiding customers through every phase from contract to sustained usage. Collaborate cross-functionally to ensure successful adoption and i...

Boston, MARemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$104K - $143K *

Advance clinical risk management by identifying, assessing, and mitigating risks in patient care and operations. Collaborate with leaders to enhance safety and compliance, ensuring effective strategie...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.