Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Mgr, Risk Adjustment Vendor & Performance Mgmt
$109K - $149K *
Unlock vendor performance by leading analytics and risk adjustment initiatives across healthcare programs. Drive strategy, manage relationships, and ensure accurate reporting to optimize operational s...
Reposted 5 days ago
Strategy & Operations Manager, In-person (Remote)
$100K - $120K *
Empower the growth of in-person behavioral healthcare by leading strategic operations, enhancing provider acquisition, and ensuring compliance. Drive high-impact initiatives while collaborating across...
3 weeks ago
Director, CRM Product Management
$150K - $180K *
Accelerate your career by leading CRM product management, shaping the roadmap for Salesforce solutions, and driving innovation in AI integration while collaborating with cross-functional teams to enha...
1 week ago
$150K - $190K *
Accelerate customer success by leading post-sales deployments of innovative AI solutions in healthcare. Shape operational strategies to ensure measurable outcomes, adoption, and expansion while drivin...
Reposted 3 weeks ago
$185K - $220K *
Join a team that's redefining engineering service delivery for legal and professional clients. Lead a dynamic organization focused on operational excellence, client satisfaction, and continuous improv...
3 weeks ago
Senior Director, Client Growth & Strategy, Federal Civilian
$200K - $250K *
Join a team that's shaping growth strategies for Federal Civilian accounts. Leverage your expertise in federal markets to drive business development, capture opportunities, and enhance customer relati...
4 days ago
Clinical Liaison and Market Dev. Leader
$110K - $130K *
Join a team that's driving innovation in transplant advocacy by integrating business development, marketing, and medical expertise. Collaborate with key stakeholders to enhance KOL engagement and mark...
2 weeks ago
Executive Director - Cyber Defense Operations
$175K - $334K *
Drive your career by leading a global team in cybersecurity operations, shaping enterprise-wide strategies for detection and response, and ensuring rapid threat remediation while enhancing operational...
Reposted 3 days ago
Epic Clinical Sr. Reporting Business Analyst
$95K - $115K *
Unlock potential by leading analytics initiatives, transforming data into actionable insights, and mentoring junior analysts. Collaborate with stakeholders to enhance reporting solutions and drive ope...
2 weeks ago
Senior Compensation Program Manager
$99K - $144K *
Transform workforce strategies by leading enterprise-level compensation initiatives. Collaborate across HR and business teams to drive impactful change, utilizing data analysis and project management...
1 week ago
Clinical Research Associate (CRA)
$80K - $95K *
Join a team that's redefining clinical research! As a CRA, you'll build site relationships, ensure compliance, and drive patient recruitment while enjoying world-class training and technology. Experie...
1 week ago
$110K - $138K *
Join a dynamic team to drive clinical trial success in Oncology, fostering strong investigator relationships and strategic enrollment strategies. Leverage your expertise to enhance trial execution and...
1 week ago
Vice President - Strategic Collaborations
$240K - $260K *
Elevate collaborative efforts by building and managing executive-level relationships within the Precision Oncology Alliance and leading institutions. This role focuses on strategic partnerships and en...
Reposted 3 weeks ago
Market CEO - North Carolina and Virginia
$210K - $250K *
Drive regional growth and performance by overseeing facilities, managing key relationships, and implementing corporate initiatives to ensure high-quality patient care and operational excellence across...
5 days ago
REMOTE: Strategy & Operations Manager
$70K - $120K *
Champion strategic initiatives to enhance sales development and marketing operations, driving growth through data-driven insights and cross-functional collaboration. Optimize processes and implement s...
1 week ago
Director, Managed Markets-National Accounts
$235K - $270K *
Lead strategic access initiatives and relationships with key stakeholders in managed markets, ensuring alignment and execution of the access strategy for a growing portfolio of therapies. Drive contra...
1 week ago
Sr. CRA, FSP - Surgical / Medical Device - Central region
$130K - $133K *
Advance clinical research by leading site monitoring and management efforts. Ensure compliance with regulatory standards while overseeing study protocols and data integrity. Collaborate with teams to...
1 week ago
Nurse Manager - UW Medical Center Surgical Services
$113K - $210K *
Transform patient care by leading a dynamic surgical team, ensuring excellence in operations, compliance, and staff management while enhancing the overall patient experience in a fast-paced environmen...
6 days ago
Staff Technical Program Manager, Enterprise Transformation
$120K - $145K *
Shape complex, cross-functional programs that drive enterprise transformation, focusing on Customer Data Platform implementation and AI initiatives. Collaborate with diverse teams to ensure strategic...
6 days ago
$95K - $112K *
Transform legal operations by streamlining processes, enhancing data management, and implementing innovative technology solutions. Collaborate cross-functionally to optimize workflows and support a sc...
3 days ago
$150K - $180K *
Accelerate regional commercialization of innovative cell therapies by leading strategic initiatives, enhancing customer engagement, and ensuring optimal patient access while collaborating cross-functi...
1 week ago
Senior Manager, Obesity Coverage and Value Strategy
$144K - $195K *
Oversee value-driven strategies for obesity coverage, enhancing payer access through robust communication and market analysis, while leading cross-functional partnerships and research to optimize cove...
4 weeks ago
Associate Director, Commercial Manufacturing & Packaging
$150K - $195K *
Lead the strategy and execution of commercial drug product manufacturing, ensuring operational performance and supply security while collaborating across teams to develop effective manufacturing plans...
4 weeks ago
Associate Director, Medical Information & Medical Review
$135K - $160K *
Elevate scientific communication at a leading biotech firm by building Medical Information and Review capabilities. Drive quality and integrity in medical content while collaborating across teams to s...
2 weeks ago
$135K - $160K *
Champion regulatory strategy and lead insurance affairs, engaging with regulators and advising clients on AI and imagery use. Build a robust filing program and ensure compliance while shaping industry...
1 week ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.