Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Experienced Clinical Research Associate | Regionally Aligned Across US
$80K - $95K *
Join a dynamic team to oversee clinical research activities, ensuring compliance with regulatory standards and driving site performance. Collaborate with stakeholders to enhance patient safety and dat...
1 week ago
Senior Manager, Provider Network Performance
$107K - $199K *
Champion the development of network performance analytics by designing solutions that transform data to support comprehensive contracting analytics and modeling applications, enhancing financial insig...
6 days ago
$225K - $250K *
Transform operations by leading a diverse team to enhance profitability and efficiency across multiple sites, while building strategic relationships with clients and driving growth initiatives in the...
4 days ago
Sr. CTM/Associate Director, QED Alliance support
$145K - $177K *
Join a team that's dedicated to advancing clinical trials for rare diseases. As a Senior Clinical Trial Manager, you'll lead operational execution, ensuring compliance and quality while fostering stro...
3 weeks ago
$120K - $145K *
Drive your career with a pivotal role in shaping product strategy and delivery, enhancing member experiences in healthcare. Collaborate across teams to define problems, prioritize outcomes, and levera...
3 weeks ago
Senior Manager, Customer Success Applications
$156K - $234K *
Join a dynamic team to lead the development of AI-driven customer success platforms, enhancing post-sale experiences through innovative technology and automation, while collaborating closely with engi...
Reposted 3 weeks ago
Senior Analyst, Marketing Operations
$72K - $113K *
Deliver impactful insights by owning our marketing tech ecosystem, maximizing HubSpot and Salesforce integration, and ensuring data integrity. Collaborate across teams to translate needs into actions...
Reposted 3 weeks ago
Senior Site Identification and Relationship Manager - US/Mexico City/Argentina - Remote
$90K - $178K *
Drive post-award site identification efforts by developing strategies, managing feasibility questionnaires, training resources, and coordinating outreach to ensure optimal site activation and client c...
Reposted 5 days ago
Sr. Director, Revenue Operations - AMER
$198K - $298K *
Lead the charge in shaping the AMER Revenue Operations strategy, driving operational excellence and predictable outcomes. Collaborate with executive leadership to optimize sales processes and build a...
4 days ago
NeuroPsych Account Specialist - Chicago North
$123K - $168K *
Empower your career by driving product growth and building relationships with healthcare professionals. Utilize your expertise to educate and manage accounts, ensuring the success of Neurocrine produc...
3 weeks ago
Associate Creative Director, Design
$160K - $200K *
Empower creative excellence by leading diverse teams to craft innovative designs across digital and immersive platforms. Drive impactful storytelling and mentor talent while balancing hands-on design...
3 days ago
Principal, Data Governance Platforms
$149K - $224K *
Shape the future of data governance by leading the design and implementation of enterprise platforms that ensure data integrity, quality, and compliance across the organization, while collaborating wi...
2 weeks ago
MRD Regional Sales Director, Dallas
$150K - $200K *
Shape the future of oncology diagnostics by leading a dynamic sales team to exceed revenue goals. Drive strategic initiatives, develop key customer relationships, and implement innovative sales strate...
Today
Assistant General Counsel - Managed Services Organization
$150K - $235K *
Elevate your legal career by delivering strategic counsel and effective services to Managed Services Organizations and physician practices, while managing complex legal projects and mentoring a team i...
1 week ago
Sr. Program Manager (Healthcare)
$120K - $140K *
Engage in leading complex, cross-functional programs for healthcare clients. Drive strategic initiatives, manage risks, and enhance stakeholder communication while delivering impactful results in a dy...
3 weeks ago
Manager, Compliance Risk Adjustment
$87K - $157K *
Join a team that's dedicated to managing external audits for Risk Adjustment processes. Oversee audit deliverables, collaborate with stakeholders, and ensure compliance while driving continuous improv...
3 weeks ago
Head of Customer Success, Payer & Employer
$137K - $205K *
Transform customer relationships by leading a team to enhance account management, drive product adoption, and ensure client success in the healthcare sector, fostering growth and retention across dive...
3 weeks ago
$144K - $173K *
Shape the future of pharmaceutical media by leading client strategy and integrated media delivery. Drive audience engagement, manage high-impact relationships, and leverage data insights to achieve me...
1 week ago
$80K - $95K *
Drive client success by managing relationships, optimizing collections, and resolving issues. Collaborate with diverse stakeholders to ensure satisfaction and compliance while leading a team to enhanc...
1 week ago
Senior Clinical Research Associate - Psychiatry (US, Central)
$97K - $193K *
Join a dynamic team as a Senior CRA, ensuring high-quality clinical studies through expert oversight, proactive monitoring, and strong partnerships with sites and sponsors. Your leadership will drive...
Reposted 5 days ago
$120K - $150K *
Drive the marketing strategy and execution from the ground up. Collaborate with cross-functional teams to build scalable demand-generation programs to boost qualified pipeline and revenue for innovati...
Reposted 4 weeks ago
$190K - $240K *
Shape the future of product management by leading the vision and roadmap for innovative solutions in the Human Data Trial lifecycle, collaborating closely with engineering and mentoring junior team me...
1 week ago
$68K - $105K *
Join a dynamic team to configure, implement, and support Epic ClinDoc applications. Engage in business analysis, system design, and user support to enhance workflows and resolve issues, contributing t...
2 weeks ago
Director, Software Engineering
$150K - $180K *
Lead and inspire a blended team of developers to enhance AI-driven legal automation platforms, ensuring technical excellence, delivery, and collaboration across functions while managing architecture...
2 weeks ago
Director, Marketing Programs | Remote, USA
$150K - $180K *
Empower our marketing initiatives by leading enterprise programs and events strategy. Drive alignment across teams, manage budgets, and ensure impactful experiences that enhance brand visibility and s...
2 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.