Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Assoc Dir, Neuro Thought Leader Liaison (Northeast region)
$190K - $225K *
Transform healthcare engagement by leading KOL strategy and insight generation in rare diseases. Collaborate with thought leaders to influence brand strategies and drive educational initiatives in a d...
4 weeks ago
Senior Scientific Director - Publications (Oncology)
$150K - $180K *
Drive impactful scientific communication by overseeing content development across therapeutic areas, ensuring strategic alignment with client goals while managing a team and collaborating with various...
3 weeks ago
Clinical Project Manager - Oncology (Client Dedicated/Remote)
$120K - $135K *
Empower clinical research excellence by managing projects that ensure compliance with regulatory requirements and drive successful study delivery from initiation to closeout. Collaborate with interdis...
Reposted 3 weeks ago
$150K - $180K *
Empower innovation by leading the data and ML strategy, driving product outcomes through analytics and machine learning, and building a high-impact team in a growth-oriented tech environment...
Reposted 3 weeks ago
Staff Product Marketing Manager (PMM), Patient Growth
$190K - $238K *
Lead the transformation of patient experiences in mental health care by shaping marketing strategies that drive acquisition, activation, and retention. Collaborate across teams to enhance messaging an...
5 days ago
Senior Implementation Project Manager
$110K - $130K *
Manage implementation projects, ensuring clear ownership and accountability across complex customer engagements while maintaining rigorous oversight of critical paths and deliverables for timely launc...
Reposted 3 weeks ago
$116K - $193K *
Help shape privacy governance across digital platforms by managing initiatives, fostering collaboration, and ensuring compliance with privacy standards. Drive strategic actions and measurable outcomes...
Today
Senior Clinical Research Associate- CNS - (Mid Atlantic)
$97K - $193K *
Lead the charge in advancing clinical research by managing site activities throughout the study lifecycle, ensuring high-quality trial delivery, and collaborating with investigative sites and study te...
Today
$86K - $121K *
Join a team that's redefining subrogation leadership by driving strategic growth, optimizing operations, and enhancing client relationships. This role combines hands-on management with innovative tech...
3 weeks ago
Director, Business Systems & Solution Architecture (D365 F&O)
$155K - $170K *
Lead the charge in shaping enterprise business solutions through hands-on architecture and delivery in Microsoft Dynamics 365 Finance & Operations, focusing on integration, process optimization, and o...
Reposted 1 week ago
$95K - $115K *
Optimize customer success by driving engagement and retention, ensuring clients maximize value from services. Collaborate with teams to enhance the customer experience and advocate for their needs, co...
1 week ago
Director, HR Technology & Data
$110K - $130K *
Join a team that's transforming HR technology and data governance to enhance organizational effectiveness. Lead a global team in driving data-driven decision-making and innovative solutions that prote...
1 week ago
$149K - $248K *
Champion client engagement and operational excellence by managing consulting teams, driving quality standards, and fostering relationships within Military Health Systems. Lead new business development...
1 week ago
Senior Customer Succes Manager
$110K - $130K *
Pioneer customer success by nurturing strategic relationships, driving product adoption, and ensuring satisfaction. Leverage your expertise to mentor junior team members and shape customer success str...
3 weeks ago
$69K - $101K *
Unlock potential by delivering comprehensive clinical care management services, enhancing health outcomes for diverse populations through assessment, care planning, and coordination across multiple he...
5 days ago
Senior Director, Regulatory Affairs
$211K - $281K *
Champion regulatory excellence by leading U.S. FDA engagement and strategy for product development, ensuring timely approvals and compliance while driving cross-functional collaboration and organizati...
3 weeks ago
Head of Go-to-Market, AI Care Operations
$145K - $330K *
Shape the future of healthcare by leading go-to-market strategies for AI Care Operations. Drive product positioning, competitive differentiation, and enable commercial teams to effectively communicate...
2 weeks ago
Manager, Simulation Operations
$182K - $263K *
Drive simulation operations by leading a hybrid team to execute high-quality tests, establish evaluation metrics, and enhance processes using AI for improved operational performance across virtual tes...
Reposted 3 weeks ago
Senior Clinical Research Associate - Cns
$95K - $115K *
Champion clinical excellence by overseeing studies with a blend of remote and on-site monitoring. Leverage your expertise in CNS, oncology, or metabolic indications to ensure compliance and enhance si...
3 weeks ago
$110K - $130K *
Advance your career by leading complex divestiture initiatives. Drive alignment and manage interdependencies in a transformative environment, ensuring successful execution across varied business funct...
Reposted 3 weeks ago
Integrated Care Clinical Manager - RN - Lynn, MA
$80K - $120K *
Champion integrated care management by coordinating health services for dually-eligible enrollees with complex needs. Engage with members in community settings to enhance health outcomes and quality o...
1 week ago
$101K - $126K *
Join a dynamic team to lead complex projects, ensuring timely delivery and alignment with strategic goals. Collaborate across departments, manage risks, and mentor others while leveraging best practic...
2 weeks ago
$125K - $150K *
The Director of Government Reimbursement will serve in a consultancy capacity, advising large health systems on managing and optimizing healthcare reimbursement processes, particularly focusing on Med...
Reposted 4 weeks ago
$80K - $95K *
Drive data integrity and operational excellence by resolving complex payer data issues, collaborating across teams, and enhancing data quality for value-based care initiatives. Play a key role in opti...
3 weeks ago
Director of Client Services (Remote)
$80K - $154K *
Strategize and lead client services to enhance business performance, drive operational excellence, and ensure client satisfaction across diverse teams and portfolios. Foster talent development and ris...
2 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.