Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
More
1
caret down

$124K - $206K *

Drive the end-to-end revenue marketing strategy to enhance pipeline growth, accelerate revenue, and strengthen market positioning. Lead a cross-functional team to optimize performance and scale impact...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$233K - $303K *

Transform stakeholder advocacy by leading initiatives, fostering collaboration, and aligning strategies with evolving market dynamics to enhance patient access to essential treatments in the biopharma...

Hampton, NJRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$126K - $173K *

Transform provider onboarding and medical documentation processes to enhance compliance and operational efficiency. Lead teams in executing strategies that ensure timely, accurate documentation while...

Kentucky, USRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$150K - $206K *

Drive strategic risk management initiatives by leading regulatory audits, enhancing operational processes, and fostering cross-functional collaboration to minimize financial impacts and improve audit...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Drive client satisfaction as a Senior Project Manager, overseeing eDiscovery projects, managing budgets, and consulting on best practices. Lead teams, enhance workflows, and ensure timely delivery whi...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$268K - $466K *

Champion early clinical development in a dynamic team. Lead clinical research physician role for first-in-human studies, ensuring compliance and collaboration across scientific and regulatory areas to...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$203K - $319K *

Lead and optimize commercial operations to drive growth, enhance revenue strategies, and streamline processes. Collaborate with cross-functional teams to ensure effective execution of sales initiative...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Lead the strategic growth and operational excellence of palliative care services across multiple markets, ensuring high-quality patient-centered care and compliance with regulatory standards while fos...

Mckinney, TXRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $294K *

Drive innovation in drug development as a clinical pharmacology expert, leading strategic initiatives for both small and large molecules. Collaborate with diverse teams, communicate with regulatory ag...

Ridgefield, CTRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform healthcare delivery by leading program initiatives that drive partner success in value-based care. Utilize data-driven strategies to manage launch processes, ensuring alignment across teams...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Advance financial operations by managing project finance teams, enhancing reporting processes, and supporting month-end close activities. Collaborate with stakeholders to ensure accurate revenue recog...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Advance your career by managing financial operations for project teams, enhancing reporting accuracy, and leading financial analysis to support clinical trials and strategic decision-making...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $200K *

Unlock potential by driving sales strategies in the healthcare sector. Collaborate with C-Level executives, generate new opportunities, and enhance market presence while navigating complex enterprise...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $231K *

Lead and develop recruitment operations to enhance client engagement and project success. Collaborate across teams to translate client needs into actionable recruitment strategies, ensuring optimal de...

Pennsylvania, USRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$262K - $404K *

Optimize patient care and operational leadership as you manage Anesthesia APP teams, ensure regulatory compliance, and build strong client relationships while driving growth in practices and enhancing...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $215K *

Launch impactful product initiatives by bridging engineering and design while driving user-centered solutions and leveraging AI tools for enhanced workflows in a high-growth environment...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$174K - $374K *

Drive behavioral health care management, ensuring quality oversight, program development, and efficiency enhancements while leading a multidisciplinary team. Contribute to medical necessity decisions...

Texas, USRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$300K *

Elevate healthcare delivery by leading a dedicated team in clinical evaluations, ensuring best practices while providing client-facing support and expertise in medical claims, regulations, and emergin...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Engage a dynamic team to drive sales growth by coordinating in-field activities, implementing strategic plans, and fostering collaboration to achieve targets while developing team capabilities and mar...

New London, CTRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $181K *

Lead the charge in enhancing market and provider performance through strategic initiatives, project management, and cross-functional collaboration, ensuring operational excellence and improved member...

Long Beach, CARemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $185K *

Unlock your potential by leading a dynamic team to drive channel partnerships, transforming opportunities into revenue-generating relationships across diverse verticals in a fast-growing ecosystem...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Transform enterprise service delivery by leading cross-center operations, enhancing efficiency, and ensuring high-quality IT services across multiple locations. Drive initiatives that improve performa...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$90K - $110K *

Unlock potential by leading credentialing and payer operations, ensuring compliance and efficiency across health plans. Collaborate with teams to resolve issues, enhance processes, and maintain strong...

Southlake, TXRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Lead statistical strategy and oversight for oncology clinical trials, ensuring quality deliverables and regulatory compliance while collaborating with cross-functional teams to drive clinical developm...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$228K - $309K *

Drive strategic pharmacy partnerships and enhance patient access to Amgen medicines. Lead a high-performing team, develop customer strategies, and engage with senior leaders to optimize the pharmacy e...

Thousand Oaks, CARemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.