Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$125K - $185K *

Transform the future of healthcare sourcing by leading strategic initiatives, managing a dedicated team, and driving cost-saving projects across Facilities categories to ensure high-quality service de...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$140K - $160K *

Shape the future of healthcare by building strategic partnerships that enhance behavioral health referrals. Collaborate with leadership to drive growth, develop tailored solutions, and maintain strong...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Join a dynamic team to lead clinical operations, ensuring quality care and compliance across medical specialties. Collaborate with management and providers to enhance communication and operational eff...

New York, NYRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Drive your career with a pivotal role in business development, focusing on lead generation and relationship building to enhance pipeline growth and support sales objectives across North America...

Mississauga, ONRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by driving business growth through lead generation, relationship building, and strategic engagement. Collaborate with sales teams to identify opportunities and close deals, ensuring a...

Raleigh, NCRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's driving growth by identifying and developing new business opportunities. You'll engage prospects, nurture relationships, and support the sales team in achieving corporate objectives...

Denver, CORemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$255K - $424K *

Lead the development and execution of Immunology access services strategy, ensuring seamless patient and provider experiences. Collaborate cross-functionally to enhance reimbursement initiatives and d...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$91K - $137K *

Shape the future of clinical research by managing site operations, ensuring patient safety, and maintaining data integrity. Collaborate with study teams to oversee monitoring activities and drive succ...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$91K - $137K *

Empower your career by managing clinical research sites, ensuring patient safety, and maintaining data integrity. Collaborate with teams to oversee study implementation and monitoring, while enhancing...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$72K - $94K *

Transform patient access operations by leading centralized support functions, optimizing workflows, and enhancing service quality across multiple regions. Drive continuous improvement and develop lead...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Elevate healthcare through strategic AI product management, driving innovation and lifecycle management of AI solutions. Collaborate cross-functionally to align business objectives with customer needs...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to advancing global studies in Neurology, Psych, and Rare Disease. Lead project teams, manage operations, and ensure timely delivery to exceed client expectations while ac...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate client integration projects by leading implementation of Prancer RTSM/Admin systems. Engage with clients, manage project activities, and resolve issues while ensuring high-quality standards in...

Wellesley, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive your career with a strategic role focused on enhancing project management standards and integrating enterprise initiatives. Collaborate with leaders to improve clarity, prioritization, and execu...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Champion global physical security and resiliency initiatives by providing strategic leadership to enhance safety for employees and assets while driving compliance across all company operations and thi...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $185K *

Champion strategic payer engagement to enhance access and reimbursement across a national portfolio. Drive medical policy influence and build relationships with key stakeholders to expand coverage and...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$98K - $155K *

Shape the future of healthcare by driving strategic growth initiatives, forging partnerships, and executing acquisitions across a diverse regional portfolio. Collaborate with leaders to enhance market...

New York, NYRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$130K *

Lead the charge in safeguarding and risk management for behavioral health services, ensuring compliance with regulatory frameworks while driving user satisfaction and engagement through strategic coll...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Transform the creative landscape by leading innovative art direction and visual storytelling. Collaborate with a dynamic team to craft compelling concepts that resonate with our brand vision and inspi...

Chicago, ILRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$325K - $375K *

Lead the charge in driving revenue growth by building and mentoring a high-performing sales team in the Mid-Enterprise segment, focusing on customer acquisition and market penetration in a competitive...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $250K *

Shape the future of global sales strategy by leading initiatives that drive partner growth and sales enablement. Collaborate with cross-functional teams to optimize processes, enhance capabilities, an...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$159K - $273K *

Join a team that's shaping the future of epidemiology by leading innovative research initiatives, fostering scientific excellence, and driving client impact across diverse sectors. Leverage your exper...

Boston, MARemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$174K - $374K *

Shape the future of healthcare by overseeing medical policy implementation and enhancing clinical programs. Collaborate with teams to ensure quality care and effective medical management across the co...

Florida, USRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $95K *

Drive operational excellence by leading projects across teams, enhancing efficiency, managing stakeholders, and ensuring timely delivery. Collaborate within a dynamic environment dedicated to improvin...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$92K - $124K *

Partner with us to enhance legal operations and implement eDiscovery processes. You'll lead customer data privacy initiatives, improving cross-functional collaboration and response strategies for comp...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.