Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
$95K - $115K *
Champion the successful delivery of projects and technology initiatives by coordinating cross-functional teams and managing risks, ensuring timely and high-quality outcomes that align with business ob...
2 weeks ago
$100K - $120K *
Elevate clinical research by assisting with study design, medical monitoring, and compliance to ensure effective execution of clinical trials and contribute positively to patient outcomes in alignment...
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Engage with strategic Oracle customers to drive success through relationship management, implementation guidance, and value realization. Champion customer outcomes and optimize their journey with Redw...
4 days ago
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$230K - $260K *
Oversee regional sales strategies and lead a team to drive oncology product sales. Collaborate cross-functionally to enhance market insights and ensure compliance while fostering team development and...
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$230K - $368K *
Elevate global BD Excellence capabilities by defining strategies, leading transformation initiatives, and partnering with stakeholders to drive measurable improvement in operational performance and or...
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Transform the landscape of patient safety by leading medical safety initiatives for gene therapy products, ensuring rigorous safety surveillance and risk management practices while collaborating close...
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Optimize quality operations for large-scale data pipelines, ensuring high standards and consistency across diverse datasets. Lead a team to enhance efficiency and reliability in audio data processing...
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Regional Business Director - LA/Hawaii
$180K - $210K *
Elevate our sales strategy by leading a dynamic team of account managers and specialists. Drive growth in the oncology market through effective coaching, relationship building, and strategic planning...
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Transform your career by partnering with teams to drive strategic growth through legal expertise in healthcare contracts, negotiations, and compliance. Collaborate with leadership to optimize performa...
3 weeks ago
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Lead the charge in developing and executing CMC strategies for antibody-based radiopharmaceuticals, ensuring alignment with Stage-Gate requirements while managing cross-functional teams and external p...
Today
Senior Manager, RCM Optimization & Strategy
$130K - $145K *
Elevate revenue cycle management by analyzing workflows, optimizing processes, and driving strategic improvements. Collaborate across teams to enhance billing accuracy and maximize collections in a fu...
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Elevate service operations by developing strategies that enhance performance, drive accountability, and ensure customer satisfaction through effective leadership and operational excellence in a comple...
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Director, Technology Innovation COE
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Transform the future of supply chain technology by leading innovation initiatives, managing a structured evaluation process, and engaging stakeholders to drive measurable value and strategic alignment...
1 week ago
Director of Sales - MDLive - Remote
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Drive new logo acquisition and revenue growth in the healthcare sector by leading complex sales processes, building executive relationships, and collaborating with cross-functional teams to deliver ta...
6 days ago
Director, Digital Strategy & Operations
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Shape the future of digital product strategy by leading cross-functional teams, driving innovation, and ensuring alignment with business goals. Your expertise will enhance customer experiences and fos...
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Director, Biologics CMC Technical Writing
$189K - $246K *
Shape the future of biologic product development by leading CMC documentation strategy and execution, ensuring regulatory compliance and scientific rigor across submissions. Collaborate with cross-fun...
3 weeks ago
Director Of Sales, Community Health Centers, East
$145K - $155K *
Pioneer strategic growth in healthcare by engaging C-suite executives, driving partnerships, and expanding market share within Community Health Centers across the Eastern U.S. This consultative role d...
2 weeks ago
Clinical Documentation Manager
$73K - $115K *
Unlock the potential of clinical documentation integrity by driving ICD-10-CM coding accuracy and enhancing provider education. Collaborate with cross-functional teams to support risk adjustment initi...
1 week ago
Associate Director, Compliance & Revenue Integrity
$110K - $130K *
Shape the future of healthcare revenue integrity by ensuring compliance and optimizing revenue capture through strategic oversight and collaboration across departments, fostering a culture of accounta...
1 week ago
$100K - $120K *
Oversee clinical trial management, ensuring quality deliverables and compliance. Collaborate with teams to design protocols, analyze data, and address challenges, driving successful execution of innov...
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Clinical Project Manager II, Oncology- Remote US
$135K - $150K *
Lead the charge in managing clinical projects, ensuring timely delivery, budget adherence, and quality standards while fostering high-performing teams and client relationships in a dynamic, multi-cult...
Reposted yesterday
Associate Director, Innovation Strategy and Execution
$110K - $130K *
Optimize the Innovation portfolio by leading high-impact projects, collaborating with senior leaders, and driving strategic initiatives. Your role will ensure seamless operations and foster growth in...
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$130K - $145K *
Empower business growth by leveraging advanced analytics to drive data-driven decision-making across Commercial, Operations, and Finance, transforming complex data into actionable insights for measura...
3 weeks ago
$110K *
Elevate channel strategy and partner relationships to drive revenue growth, enhance market positioning, and ensure effective collaboration across teams, while managing negotiations and performance met...
3 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.