Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Manager, Clinical Study Operations
$115K - $135K *
Transform clinical trial operations by leading a dynamic team to ensure seamless execution of device-based studies, from feasibility to close-out, while driving process improvements and fostering cros...
1 week ago
$210K - $260K *
Join a fast-paced team of medical professionals to evaluate and enhance service appropriateness through evidence-based guidelines, impacting quality patient outcomes across multiple specialties while...
Reposted 3 weeks ago
Director, Process & Operations Management, Medical and Scientific Affairs (MSA)
$150K - $258K *
Elevate your career by leading strategic initiatives in Medical and Scientific Affairs. Drive portfolio governance, enhance operational excellence, and foster cross-functional collaboration to deliver...
1 week ago
$210K - $250K *
Drive the growth of a therapeutic portfolio by leveraging medical expertise and overseeing clinical trials. Collaborate across teams to shape strategies in cell and gene therapy, ensuring innovative...
6 days ago
Senior Medical Director, Medical Affairs - Rheumatology (US)
$175K - $348K *
Transform clinical research through expert medical management and support. Collaborate with teams to ensure protocol integrity, provide training, and contribute to business development while maintaini...
Reposted 5 days ago
$110K - $130K *
Lead the charge in strategic program management, overseeing project delivery and team development. Drive successful outcomes through effective staffing, risk management, and stakeholder collaboration...
1 week ago
Senior Director, Program Management, Regulatory Affairs
$160K - $190K *
Transform regulatory strategies by leading cross-functional teams to ensure timely submissions and compliance for our innovative gene therapy pipeline, driving excellence in pediatric neurodegenerativ...
Today
Director, Quality Assurance (Clinical)
$175K - $236K *
Champion quality excellence by leading a dynamic team to enhance compliance and drive continuous improvement in clinical development. Collaborate across functions to ensure regulatory readiness and de...
3 days ago
Vice President, Clinical Operations
$200K - $250K *
Make your mark at the forefront of clinical operations, driving global studies from strategy to execution while ensuring operational integration across teams and vendors for successful Phase 3 program...
3 weeks ago
$140K - $170K *
Shape the success of enterprise health systems by leading full implementations. Collaborate cross-functionally to manage project lifecycles, mitigate risks, and ensure smooth transitions to customer s...
4 weeks ago
$111K - $159K *
Lead clinical operations in review of medical certifications for leave requests. Build and manage a dedicated team, standardize workflows, and ensure compliance while driving continuous improvements i...
Reposted 4 days ago
Associate Director, Patient Recruitment and Retention Execution Manager
$194K - $266K *
Champion patient engagement strategies by leading a dynamic team focused on optimizing recruitment and retention across clinical trials. Drive performance, enhance collaboration, and ensure successful...
4 days ago
Director, Biometrics Strategy and Business Development
$125K - $150K *
Drive revenue growth and strategic partnerships in biometrics services, focusing on client relationships and market strategy. Collaborate with teams to deliver innovative solutions and position the or...
2 weeks ago
Associate Director, Clinical Science
$180K - $240K *
Lead scientific strategy for clinical development of BHB-1893, collaborating with cross-functional teams to ensure data integrity and regulatory compliance. Drive protocol design, data analysis, and e...
1 week ago
$115K - $145K *
Lead clinical research projects, ensuring compliance with regulations and timelines. Collaborate with teams and sponsors, manage study functions, and drive effective communication to achieve trial mil...
2 weeks ago
Program Manager, Client Services, Clinical Trial Support
$88K - $105K *
Lead the charge in managing client relationships and program performance, ensuring timely delivery of medications. Oversee budgets, facilitate communication between stakeholders, and drive successful...
6 days ago
Associate Director, CMC Operations
$155K - $190K *
Manage the planning and execution of CMC operations across multiple development programs, ensuring alignment with regulatory milestones and efficient collaboration with cross-functional teams and CDMO...
1 week ago
Senior Director, Physician Experience: CareerMD
$146K - $282K *
Join us in enhancing physician relationships and engagement through strategic leadership, managing a dynamic team, and executing impactful career events that foster lifelong partnerships with healthca...
Reposted 4 days ago
Director, Business Development
$120K - $150K *
Drive full-cycle sales for global clinical operations, fostering client relationships and developing strategic plans for service growth in alignment with company objectives...
Reposted 1 week ago
$180K - $195K *
Join a dynamic team to lead and manage clinical trials, ensuring timely execution and compliance. Collaborate with cross-functional partners and vendors to drive operational success in immunology rese...
3 weeks ago
$120K - $145K *
Champion the development of clinical operations by managing a network of providers, establishing policies, and enhancing quality programs. Collaborate with leadership to ensure operational excellence...
4 days ago
$115K - $140K *
Optimize customer engagement by designing connected experiences that bridge strategy and execution. Lead cross-functional teams to ensure seamless journey mapping, activation, and continuous improveme...
1 week ago
$135K - $160K *
Join a team that's redefining People Operations by leading strategic initiatives in benefits, payroll, and automation. Drive impactful change while managing a high-performing team and collaborating ac...
1 week ago
Director, Clinical Quality Assurance
$195K - $256K *
Elevate clinical quality assurance by designing and executing strategies for compliance, audit management, and oversight of global clinical operations. Collaborate with stakeholders to ensure adherenc...
6 days ago
Medical Director, Clinical Partnerships
$200K - $250K *
Transform provider engagement by leading peer-to-peer conversations and ensuring clinical governance. Leverage your medical expertise to enhance patient safety and optimize drug strategies while repre...
Reposted 3 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.