Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Chief Scientist, Director, Clinical Research Lab
$150K - $180K *
Unlock potential by leading a cutting-edge Clinical Research Laboratory, driving innovation in testing services, and ensuring regulatory compliance while collaborating with diverse stakeholders to enh...
3 days ago
Physical Medicine and Rehabilitation Medical Director
$206K - $413K *
Join our team to lead in Physical Medicine and Rehabilitation, providing oversight, improving utilization, and guiding medical policy. Collaborate with staff and external partners to enhance healthcar...
Reposted 3 days ago
Senior Scientific Director - Oncology (Medical Affairs & Commercial Medical Education)
$160K - $190K *
Champion the development and oversight of scientific content across diverse therapeutic areas while managing client relationships and brand strategy for multiple accounts, ensuring high-quality and im...
Reposted 3 weeks ago
Lead Director, Business Operations and Strategy
$100K - $231K *
Join a dynamic team as a strategic advisor, driving clinical priorities and operational excellence. Collaborate with leaders to translate strategy into action, enhance provider performance, and suppor...
3 days ago
$162K - $238K *
Design and optimize R&D operations to enhance organizational effectiveness through data-driven insights, collaboration, and governance. Partner cross-functionally to drive continuous improvement and e...
3 weeks ago
Director, Client Growth & Strategy, HHS
$150K - $200K *
Transform client relationships and drive growth strategies within HHS, leveraging market insights and technology to identify opportunities and enhance mission impact. Engage directly with stakeholders...
4 days ago
Associate Director, Local Delivery Lead/Local Trial Manager
$129K - $216K *
Pioneer clinical excellence in this remote role, leading US oncology study delivery. Collaborate with cross-functional teams to meet recruitment, quality, and compliance objectives while fostering inn...
3 weeks ago
$120K - $150K *
Lead the charge in elevating client success through strategic relationship management, team development, and robust operational frameworks to ensure exceptional service delivery and client satisfactio...
4 weeks ago
Executive Director, Account Management
$255K - $310K *
Lead a high-performing team to execute market access strategies, optimize payer engagement, and enhance product positioning. Drive collaboration across stakeholders to ensure effective reimbursement a...
4 days ago
Senior Director, Medical Affairs Strategy & Launch--Hematology
$247K - $309K *
Unlock potential by leading medical strategy for hematologic malignancies. Collaborate cross-functionally to drive evidence generation, stakeholder engagement, and launch readiness, ensuring impactful...
1 week ago
Director, Funded Billing & Collections
$110K - $130K *
Drive operational excellence at a leading healthcare organization by leading funded medical accounts receivable. Build a high-performing collections team, enhance cash flow, and ensure compliance whil...
6 days ago
$69K - $101K *
Lead the charge in holistic clinical care management, enhancing health outcomes through comprehensive assessments, care planning, and coordination for diverse member populations with complex needs...
1 week ago
Associate Medical Director (RadScience)
$110K - $130K *
Join a dynamic team to lead the creation of impactful scientific content, enhancing medical education and patient outcomes. Collaborate cross-functionally, mentor writers, and drive excellence in heal...
1 week ago
Director - Product Management, LillyDirect, EMEA
$163K - $297K *
Champion the development and execution of innovative digital product strategies across EMEA, enhancing consumer experiences and driving key performance indicators in a high-growth e-commerce environme...
4 days ago
Director of Strategic Accounts - Enterprise / Clinical Healthcare
$125K - $150K *
Drive strategic growth and retention by managing high-value enterprise accounts, fostering executive relationships, and leading contract negotiations to align client objectives with innovative solutio...
5 days ago
Director, Medical Affairs - Emerging Therapies
$175K - $210K *
Transform the landscape of emerging therapies by leading strategic clinical innovation, guiding development, and ensuring regulatory readiness for novel therapeutic solutions across early- and mid-sta...
1 week ago
Medical Director (Publications)
$130K - $150K *
Champion effective publication strategies and lead scientific communication initiatives, acting as a strategic partner to clients and teams. Navigate complex medical affairs content to drive impactful...
Reposted 1 week ago
Senior Director, HR Business Partner (Remote: Boston, Raleigh, Apex-Wilmington)
$150K - $180K *
Drive impactful HR strategies in a dynamic global environment, collaborating with senior leaders to align people initiatives with business goals. Contribute to a newly forming team focused on growth a...
Reposted 1 week ago
$275K - $350K *
Lead the charge in transforming operations by integrating AI and technology to enhance member and clinician experiences, ensuring efficient care delivery and operational excellence across a distribute...
5 days ago
Sr. Accounting Transformation Lead
$150K - $206K *
Transform the accounting landscape by leading strategic initiatives that enhance operational efficiency, standardize processes, and drive technology integration, all while ensuring public company read...
3 weeks ago
Director of Revenue Cycle Management
$165K - $175K *
Drive operational excellence by leading multi-state revenue cycle management, optimizing physician billing, and enhancing payer relationships. Collaborate with stakeholders to maximize collections and...
6 days ago
Senior Consultant (Life Sciences)
$155K - $171K *
Lead transformative consulting projects by conducting in-depth research and presenting strategic recommendations. Collaborate with clients and junior team members to drive high-quality deliverables an...
3 weeks ago
Senior Director, Oncology Pharmacology
$232K - $348K *
Lead the charge in oncology pharmacology, managing scientific teams to drive drug discovery from early stages through regulatory approval while ensuring alignment across cross-functional teams...
Reposted 6 days ago
Remote Clinical Director, Neuropsychology
$170K - $195K *
Lead and inspire a remote team of neuropsychologists, ensuring high-quality, client-centered care while promoting clinical excellence and compliance in a collaborative environment. Drive operational e...
3 weeks ago
Sr. Product Manager - Patient Recruitment
$110K - $130K *
Unlock potential by leading product strategy for patient recruitment, enhancing engagement and operational efficiency. Collaborate with cross-functional teams to drive measurable outcomes and improve...
5 days ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.