Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
$127K - $216K *
Champion risk adjustment initiatives by leading enterprise-wide programs, ensuring compliance and accuracy in data reporting. Collaborate with cross-functional teams to optimize processes and enhance...
4 days ago
Director, Chronic Practice Liaison - Remote
$126K - $210K *
Lead strategic initiatives to enhance referral growth and provider engagement across chronic therapy markets. Drive collaboration among cross-functional teams to optimize patient progression and deliv...
2 weeks ago
Senior Director, Head of Analytical Development
$250K - $275K *
Transform the future of drug development by leading Analytical Development for small molecules and oligonucleotides. Drive scientific strategy, build a high-performing team, and ensure regulatory read...
2 weeks ago
Director - Statistics - Lilly Regenerative Medicines
$193K - $308K *
Join a team that's redefining statistical leadership in clinical research. Drive innovative study designs, enhance drug development effectiveness, and influence critical decisions through data-driven...
1 week ago
Director, Partnerships and Business Development - Southeast
$150K - $180K *
Transform your career by driving strategic partnerships in healthcare. Leverage your extensive relationships within benefits consulting to influence and expand business opportunities while collaborati...
Reposted 3 weeks ago
Project Director - Documentation Integrity
$100K - $120K *
Optimize clinical documentation processes across facilities while ensuring regulatory compliance and enhancing reimbursement efficiency. Leverage your expertise in behavioral health and audit readines...
3 weeks ago
$201K - $251K *
Transform workforce intelligence by leading People Analytics, establishing data governance, and driving strategic decision-making in a high-growth environment. Collaborate across functions to enhance...
2 weeks ago
Director, Business Applications
$120K - $145K *
Transform the future of business applications by leading strategy, delivery, and operations. Collaborate with multidisciplinary teams to enhance core processes and drive value through effective system...
1 week ago
Director, Patient Support Strategy & Operations (Remote Eligible)
$204K - $265K *
Pioneer patient support strategies to enhance onboarding and access for upcoming product launches. Drive program development, operations, and cross-functional collaboration to optimize patient and pro...
4 weeks ago
Senior Director Product Management
$172K - $287K *
Join us to shape the future of pharmacy by leading product strategy and innovation. Drive growth and commercialization for a diverse portfolio of healthcare technology solutions, influencing enterpris...
Reposted 1 week ago
Vice President, Client Management
$160K - $200K *
Shape the future of client management by leading strategic planning and enhancing RCM client relationships. Drive operational performance and scalability while leveraging analytics and AI to meet clie...
Yesterday
$150K - $180K *
Accelerate progress at the forefront of AI initiatives, driving strategic development and implementation across the Health Systems and Government Services unit to enhance operational excellence and cu...
6 days ago
Senior Manager, Physical Therapy
$110K - $130K *
Lead the charge in optimizing physical therapy operations, enhancing care quality and access through strategic resource allocation and team development. Collaborate across clinical functions to drive...
Today
Associate Director, Real-World Analytics Programming
$186K - $233K *
Empower the future of real-world analytics by leading programming activities for observational studies, ensuring high-quality deliverables through collaboration with cross-functional teams and innovat...
2 weeks ago
Manager, Clinical Data Manager Study Lead
$114K - $187K *
Empower clinical studies by leading data management efforts, ensuring compliance and quality throughout the trial lifecycle. Collaborate with teams to optimize processes and enhance data integrity, me...
Reposted 3 weeks ago
$250K - $286K *
Shape the future of sales by leading a dynamic team to drive new business, refine strategies, and enhance customer experiences in a fast-paced SaaS environment, while mentoring leaders and achieving a...
2 weeks ago
Director, Client Coding Integration
$120K - $145K *
Execute accurate coding practices to ensure compliance and optimal reimbursement in a dynamic healthcare environment. Collaborate with clinical teams to maintain integrity and efficiency in revenue cy...
Reposted 1 week ago
$100K - $120K *
Join a team that's driving business development across a diverse portfolio, managing accounts, generating leads, and closing sales. You'll engage with clients to deliver customized solutions while ach...
1 week ago
$110K - $130K *
Join a dynamic team as a strategic partner to senior living operators, driving adoption and ROI. Leverage your clinical expertise and commercial acumen to enhance client relationships and ensure succe...
1 week ago
Senior Director, Global Medical Affairs
$177K - $338K *
Innovate the global medical strategy for a leading drug program. Drive launch readiness, evidence generation, and cross-functional partnerships while serving as the primary medical voice in product li...
Reposted 2 weeks ago
$150K - $178K *
Optimize biosample operations in clinical trials, ensuring quality and compliance while collaborating with cross-functional teams to enhance sample management and drive innovation in biosampling strat...
1 week ago
Senior Director, Medical Affairs - Oncology
$210K - $331K *
Optimize team performance by leading field-based medical professionals, managing budgets, and executing Oncology support plans. Drive compliance and foster development through effective coaching and p...
2 weeks ago
Director, Marketing Operations
$124K - $205K *
Optimize marketing operations by managing systems, data, and processes to drive pipeline growth. Lead HubSpot and Salesforce integration, oversee lifecycle reporting, and implement AI solutions while...
3 weeks ago
Strategy and Operations Physician Enterprise Clinical SME
$125K - $235K *
Drive operational excellence in healthcare by leading transformative initiatives, optimizing workflows, and enhancing provider productivity. Collaborate with teams to deliver data-driven solutions tha...
3 days ago
Senior Budget Administrator - Clinical Trials
$100K - $161K *
Advance your career by coordinating clinical trial budgets and coverage analyses. Collaborate with stakeholders to ensure compliance and cost efficiency while mentoring junior staff and enhancing admi...
4 days ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.