Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
RN Operations Manager, One Medical Operations , Virtual Care Operations
$74K - $129K *
Elevate healthcare delivery by managing operations for a nationwide virtual medical team. Collaborate with leaders to optimize patient care, drive performance improvements, and implement innovative wo...
1 week ago
Senior Advisor, Clinical Pharmacology
$153K - $268K *
Join our team to provide expert clinical pharmacology insights, driving dose selection and study design for innovative therapies. Collaborate with cross-functional teams to translate complex data into...
1 week ago
Director, Diagnosis-Related Group Validation (DRGV)
$125K - $150K *
Unlock your potential by leading the development of innovative DRGV services, enhancing billing and coding optimization. Collaborate across teams to create scalable solutions that drive operational ex...
1 week ago
$125K - $150K *
Join a team that leads enterprise-wide financial planning and analysis. Collaborate with senior leaders to improve business performance and drive strategic financial outcomes, while managing a dedicat...
3 weeks ago
Manager, Clinical Stewardship Operations (RN)
$150K - $165K *
Build and manage clinical stewardship operations, driving client success through effective program implementation and cross-functional collaboration. Leverage clinical expertise to enhance client rela...
Today
Senior Director, Patient Recruitment - Remote
$150K - $180K *
Inspire patient recruitment strategies by leading a dynamic team, collaborating with senior management, and leveraging innovative tools to enhance enrollment across clinical trials while ensuring dive...
6 days ago
Senior Director, Revenue Operations
$170K - $195K *
Join a dynamic team as you lead Revenue Operations, driving strategy and execution for sales and renewals. Collaborate across departments to enhance processes, optimize technology, and ensure accurate...
3 days ago
Director, Operational Excellence - UHC Data and Analytics - Remote
$134K - $230K *
Champion operational excellence by leading financial planning, workforce management, and vendor governance to enhance decision-making and drive transformation within a dynamic data and analytics envir...
3 days ago
Clinical Trial Manager/Sr Clinical Trial Manager
$145K - $190K *
Join a team dedicated to advancing oncology clinical trials. In this role, you’ll manage global studies, oversee vendors, collaborate with multi-disciplinary teams, and ensure compliance with regulato...
Reposted 1 week ago
Senior Clinical Operations Manager, Canada/USA, remote
$110K - $130K *
Transform clinical operations by leading a dynamic team, ensuring high-quality trial management, and driving innovation through technology and AI solutions. Your strategic oversight will enhance perfo...
1 week ago
Director of Tier 3 and Support Engineering
$125K - $150K *
Lead the charge in enhancing customer support by managing Tier 3 Support and Support Engineering teams. Drive technical resolutions, streamline escalations, and foster team development within a dynami...
1 week ago
$110K - $130K *
Lead a high-performing team to manage comprehensive patient services, focusing on strategic operations, client relationships, and compliance. Ensure program performance meets KPIs while driving contin...
Reposted 3 weeks ago
$153K - $290K *
Transform drug discovery by leading a dynamic team in medicinal chemistry, driving innovative small-molecule candidates from concept to IND-ready status while fostering collaboration across a global n...
Today
$160K - $200K *
Join a team that's dedicated to establishing a robust Quality Management System, ensuring compliance and excellence in global clinical development and commercialization. Lead quality initiatives and f...
3 weeks ago
$210K - $250K *
Empower oncology research by leveraging real-world evidence and clinical expertise. Collaborate with cross-functional teams to develop innovative solutions that enhance cancer treatment and support bi...
1 week ago
Director, Client Media Solutions
$100K - $140K *
Drive innovative media strategies for healthcare clients, leveraging audience insights and performance data. Collaborate with cross-functional teams to enhance planning processes and deliver impactful...
4 days ago
Medical Director -Pharmacy Appeals
$223K - $313K *
Shape the future of healthcare by leveraging your clinical expertise to review Medicare drug appeals, ensuring compliance and optimal value-based care through collaboration and analysis of complex cas...
3 days ago
Medical Director (Medical Policy & Operations)
$174K - $374K *
Champion high-quality medical care by providing clinical expertise in policy and operations. Lead transactional reviews and collaborate with diverse teams to enhance healthcare delivery and efficiency...
Reposted 6 days ago
Director, Translational Pharmacokinetics - DMPK
$177K - $283K *
Unlock potential by leading pharmacokinetic modeling for early-stage drug development. Collaborate with cross-functional teams to enhance drug absorption, distribution, metabolism, and excretion (ADME...
1 week ago
$135K - $160K *
Elevate your career by leading the strategy and execution of analytics products that drive measurable value in healthcare. Collaborate across teams to transform complex data into actionable insights t...
5 days ago
Senior Director, Oncology Clinical Educators
$197K - $246K *
Lead the charge in building strategic relationships with national payers, ensuring access and reimbursement for products. Drive initiatives that enhance patient affordability while collaborating with...
1 week ago
Associate Vice President, Clinical Services - Market Access Marketing
$180K - $220K *
Champion clinical services initiatives, driving strategic content development and mentoring teams to enhance market access and client success. Lead projects, ensure compliance with standards, and reso...
Reposted 2 weeks ago
Pharmacy Operations Program Manager
$95K - $115K *
Lead the charge in optimizing pharmacy operations by managing client relationships and ensuring operational excellence. Drive performance reviews, compliance, and continuous improvement initiatives to...
Reposted 3 weeks ago
Precision Oncology Director - Remote
$150K - $180K *
Unlock your potential by leading a high-performing sales team in precision oncology. Drive strategic initiatives, foster cross-functional collaboration, and enhance patient care through innovative sal...
2 weeks ago
Assistant Director, Global Service Delivery
$100K - $120K *
Advance global service delivery by managing offshore partnerships, ensuring performance excellence, and driving operational improvements across teams to enhance productivity and quality outcomes...
3 days ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.