Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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Dentist Jobs in South Dakota

Sort By: Relevance

$100K - $120K *

Transform community health by providing comprehensive dental care in a supportive, team-oriented environment. Enjoy a fulfilling role with no weekends or call, fostering long-lasting patient relations...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Shape the future of dental care by joining a dedicated team to provide comprehensive services, build lasting patient relationships, and enhance community health in a supportive, mission-driven environ...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Transform community health by providing comprehensive dental care in a supportive environment. Collaborate with a dedicated team to enhance patient relationships and deliver high-quality services, all...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Elevate pediatric dental care by joining our collaborative team, where you'll provide exceptional treatment to children in a supportive, high-volume practice. Enjoy a fulfilling role that fosters last...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $144K *

Join a team that's dedicated to providing exceptional dental care to children. This role offers the chance to build lasting relationships in a supportive, multi-doctor environment while utilizing mode...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Shape the future of orthodontics by delivering exceptional care and innovative treatments. Join a dedicated team in a thriving practice, enhancing smiles and patient experiences across multiple locati...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive impactful training and coaching for dental practices, enhancing adoption of digital workflows and intraoral scanning. Collaborate with clinicians and leaders to ensure operational readiness and...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$93K - $132K *

Lead the charge in developing and maintaining dental coverage policies, ensuring clinical integrity and compliance. Collaborate across teams to enhance program infrastructure and support regulatory au...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$114K - $179K *

Lead the charge in shaping the social media presence for U.S. Henry Schein Dental. Drive strategy, create engaging content, and foster community interaction while collaborating with Corporate Communic...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Transform the landscape of dental negotiations by leading strategic partnerships with payers, optimizing contracts, and driving revenue growth through data-driven insights and collaborative execution...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Lead the charge in enhancing customer support by managing Tier 3 Support and Support Engineering teams. Drive technical resolutions, streamline escalations, and foster team development within a dynami...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$70K - $120K *

Drive sales success by building relationships with dental professionals, promoting innovative products, and achieving targets. Leverage your expertise to deliver exceptional customer service and suppo...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$71K - $99K *

Join a team that's dedicated to enhancing clinical practices through effective IT solutions. This role involves training, system maintenance, and collaboration with healthcare professionals to optimiz...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$113K - $178K *

Empower dental sales growth by collaborating with leadership to develop effective strategies. Build strong relationships, enhance customer offerings, and drive success across key accounts while leadin...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Join us to lead payer contracting strategies, negotiate complex agreements, and enhance reimbursement performance across diverse healthcare models while managing a high-performing team in a dynamic, r...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$75K - $90K *

Unlock new business opportunities by developing strategic marketing and sales plans. Collaborate with executives to secure and grow employer accounts, driving revenue growth and expanding market share...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$82K - $150K *

Join a team that's driving growth in the dental implant market by aggressively prospecting and converting new customers. Leverage your sales expertise to expand market share and position value-oriente...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $150K *

Champion growth by aggressively prospecting and converting new dental accounts. Leverage a hunter mentality to expand market share and position value-driven implant solutions, while collaborating with...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $150K *

Drive growth by aggressively prospecting and converting new dental accounts while expanding existing relationships. Leverage a hunter mentality to position value-oriented implant solutions and achieve...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $150K *

Join a team that's driving growth in the dental implant market by converting competitive accounts and expanding opportunities. Leverage your sales expertise to build relationships and position value-o...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $150K *

Accelerate growth by driving new customer acquisition and expanding market share within the dental implant community. Leverage a hunter mentality to convert competitive accounts and position value-ori...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $150K *

Lead the charge in expanding market presence by driving new customer acquisition and maximizing share of wallet within the dental implant community. Utilize a hunter mentality to identify opportunitie...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $150K *

Accelerate growth by driving new customer acquisition and expanding market share in the dental implant sector. Leverage a hunter mentality to convert competitive accounts and position value-oriented s...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $220K *

Shape the future of healthcare by leading a dynamic sales team in the Urology and Incontinence sector. Drive revenue growth, foster key relationships, and implement strategic initiatives to enhance ma...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$165K - $235K *

Drive the execution of DSO growth strategies, leading a team to achieve revenue targets through data-driven sales and cross-functional collaboration, while enhancing customer relationships and ensurin...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.