Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$210K - $250K *

Join a team that's dedicated to advancing electrodiagnostic medicine and outpatient musculoskeletal care. Collaborate with experts, mentor residents, and contribute to a nationally recognized rehabili...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Shape the future of clinical trials by driving business development initiatives, identifying opportunities with sponsors and CROs, and promoting CTSdatabase's services to enhance growth and profitabil...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $175K *

Explore strategic business development opportunities to foster client retention and new client acquisition. Utilize your sales expertise to create innovative strategies and deliver impactful presentat...

Pennsylvania, USRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$68K - $113K *

Lead the charge in optimizing coding accuracy and compliance by analyzing complex patient care documentation, providing expert guidance, and enhancing coder education to ensure adherence to ethical st...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Join our dynamic Cardiology team as an Advanced Practice Provider, where you'll deliver exceptional cardiovascular care across inpatient and outpatient settings, collaborating with healthcare professi...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Innovate and optimize software solutions that transform construction processes. Collaborate across teams to develop 3D visualization tools, leveraging AI and geospatial data to enhance project managem...

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Champion healthcare project delivery by managing design and construction lifecycles, ensuring compliance with quality, safety, and budget standards while fostering collaboration among stakeholders to...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$69K - $125K *

Transform regulatory insights into actionable strategies by analyzing national and state legislative activities. Collaborate with legal and business teams to ensure compliance and support effective de...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $150K *

Join a dynamic team to leverage clinical expertise in healthcare consulting, driving improvements in perinatal care and women's health. Collaborate with leaders to analyze data, share best practices...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$205K - $380K *

Accelerate progress at enterprise sales by driving strategic growth initiatives, building relationships with healthcare leaders, and leading complex sales pursuits to enhance market presence and custo...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$95K - $100K *

Join a dynamic team as a Senior Strategist, where you'll lead data-driven strategies, mentor talent, and drive innovative solutions in healthcare advertising. Collaborate with creative teams to enhanc...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$104K - $166K *

Deliver comprehensive home-based care, manage chronic diseases, and collaborate with an interdisciplinary team to enhance patient outcomes and prevent hospital visits, ensuring safe transitions for se...

Today

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Optimize cloud security by conducting assessments, identifying gaps, and delivering actionable recommendations. Collaborate with stakeholders to enhance security posture and ensure compliance with ind...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Join a team that's dedicated to enhancing patient care and experience across multiple departments. Lead nursing staff, collaborate with healthcare professionals, and ensure compliance with regulations...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$140K - $150K *

Join a team that's dedicated to transforming addiction treatment through telehealth. Collaborate with physicians to provide comprehensive care for patients with substance use disorders, ensuring a sup...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Unlock potential by driving commercial growth strategies for a product family. Collaborate across teams to translate market insights into actionable plans that enhance revenue, profitability, and cust...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$120K - $145K *

Elevate commercial growth strategies by collaborating across teams to drive revenue, profitability, and market positioning for a product family. Utilize market insights and performance data to develop...

Today

  •   11 - 15 years exp.  •   Healthcare

$208K - $220K *

Drive enterprise leadership in clinical quality and regulatory readiness, ensuring consistent standards and governance across regions. Collaborate with stakeholders to translate quality insights into...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Deliver expert advisory services to life sciences firms, optimizing government pricing strategies and ensuring compliance. Collaborate with clients to support project execution and drive impactful out...

Philadelphia, PARemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive strategic advisory services supporting life sciences clients in government pricing, compliance, and contracting; facilitating product launches while enhancing pricing frameworks for optimal enga...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$210K - $230K *

Drive your career with a dynamic role focused on enterprise B2B sales, where you'll cultivate relationships, leverage data insights, and collaborate cross-functionally to close high-value deals in a f...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$105K - $135K *

Join a team that's redefining digital agreement workflows and secure transactions. As a Mid-Level DocuSign/CLM Developer, you'll collaborate with stakeholders to enhance platform capabilities and deli...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$134K - $249K *

Lead the charge in enhancing clinical systems operations, driving efficiency and effectiveness across pharmacy initiatives while managing a dedicated team and overseeing complex workflows and data int...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $151K *

Elevate your career by representing the organization in claims-related legal matters. Provide expert legal counsel, manage litigation costs, and develop effective strategies to ensure compliance and e...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$113K - $188K *

Elevate your career by leading the strategic development of sustainability programs across international markets, focusing on carbon project design, risk management, and technical innovation to drive...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.