Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$95K - $115K *

Partner with us to enhance patient care in our Baby Friendly post-partum units. As a Women's Health Nurse Practitioner, you'll provide essential services, collaborate with a multidisciplinary team, an...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Transform the future of special education by leading compliance, program development, and staff training. Oversee a dedicated team to ensure exceptional outcomes for students while collaborating with...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$230K - $260K *

Unlock potential by joining a dedicated team of Psychiatric Nurse Practitioners focused on delivering high-quality behavioral healthcare with flexible schedules and a supportive work environment...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$187K - $257K *

Elevate global sales operations by leading forecasting, pipeline management, and productivity initiatives. Collaborate with sales leaders to enhance clarity and consistency, driving growth through inn...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$113K - $160K *

Champion the quantification of business impact from technology and transformation investments. Lead financial modeling and value realization efforts, translating insights into actionable recommendatio...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Media

$215K - $240K *

Shape the future of drug development by leading analytical strategies, ensuring compliance and optimization of processes across lifecycle stages, and collaborating with cross-functional teams and exte...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Champion a transformative product vision, leading cross-functional teams to drive strategic outcomes in a dynamic digital health environment. Shape the future of patient care and client experience whi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Deliver comprehensive psychological assessments and evidence-based interventions, guiding treatment plans for complex cases. Collaborate with interdisciplinary teams and supervise trainees while enhan...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$230K - $260K *

Unlock your potential by joining a dedicated team of Psychiatric Nurse Practitioners committed to delivering high-quality behavioral healthcare with flexible schedules and a focus on work-life balance...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Shape the future of executive recruitment by leading strategic sourcing, engaging high-level candidates, and collaborating with a dedicated team to uncover top talent. This role offers growth opportun...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Elevate the engineering team's impact by analyzing requirements, crafting user stories, and driving SaaS product development. Collaborate with stakeholders to ensure solutions meet business needs whil...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$101K - $129K *

Oversee technical services and program management in healthcare technology. Lead a team to ensure effective maintenance, compliance, and communication while fostering a positive environment and drivin...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$206K - $276K *

Optimize global site contracting activities for clinical trials, ensuring efficient execution and compliance. Engage cross-functional teams to enhance operational performance and align contracting str...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$182K - $247K *

Drive innovative clinical operations to enhance member care and outcomes. Collaborate across teams to implement strategies, optimize processes, and scale programs, ensuring seamless coordination and e...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$175K - $210K *

Lead the charge in developing innovative T-cell engagers for prostate cancer treatment. Oversee a cross-disciplinary team, driving scientific excellence and collaboration to pioneer next-generation th...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Help us lead innovative oncology research by developing cutting-edge T-cell engagers and small molecule therapeutics. Drive scientific excellence and collaboration to create impactful cancer treatment...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$107K - $145K *

Drive growth by identifying and securing new business opportunities in risk management and medical education. Collaborate with teams to develop proposals, manage sales pipelines, and ensure alignment...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $165K *

Join a dynamic team as a Managing Consultant, driving innovative solutions in Revenue Integrity. Oversee engagements, enhance client relationships, and lead project teams to optimize financial perform...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$170K - $195K *

Engage in strategic account acquisition for our Legal Technologies sector, focusing on sourcing, qualifying, and closing new enterprise accounts. Drive revenue growth through complex sales cycles whil...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$90K - $110K *

Transform healthcare for geriatric members by collaborating with physicians and interdisciplinary teams. Utilize your advanced skills to empower patients, ensuring they maintain independence and quali...

Today

  •   Less than 5 years exp.  •   Healthcare

$92K - $110K *

Champion the health of geriatric members by providing comprehensive care assessments and collaborating with interdisciplinary teams to enhance quality of life and independence in their homes and commu...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$214K - $234K *

Champion strategic payer engagement across regional markets, building relationships that enhance patient access to therapies. Connect national strategies with local execution for optimal outcomes in c...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Empower your career as you optimize our ERP platform, collaborating with stakeholders to enhance financial processes, drive efficiency, and deliver measurable business value through innovative solutio...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $114K *

Transform the health and wellness of residents by leading a dedicated care team, ensuring high standards of resident-centered care, and fostering a compassionate environment in our vibrant community...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$240K - $260K *

Join a team that's dedicated to providing expert legal guidance in consumer loan servicing. Leverage your extensive experience to support compliance, risk management, and operational strategies while...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.