Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$119K - $186K *

Manage legal services for indirect sourcing, delivering strategic counsel and project management. Negotiate vendor agreements and ensure compliance while collaborating with stakeholders to support bus...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $231K *

Transform the pharmaceutical landscape by driving value realization on rebate contracts, collaborating with cross-functional teams, and optimizing negotiation strategies to enhance financial performan...

Pennsylvania, USRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $100K *

Transform patient care by joining a dynamic clinical team dedicated to delivering high-quality behavioral healthcare. Enjoy flexible schedules and a supportive environment while making a meaningful im...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Grow your clinical expertise as you tackle diverse patient needs in a dynamic OB/GYN setting. Join a collaborative team dedicated to continuous learning and community service while delivering high-qua...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$132K - $199K *

Join a team that's committed to transparency in clinical trials, ensuring compliance with global disclosure regulations. This role blends operational and strategic tasks, fostering collaboration and q...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $110K *

Elevate your career by leveraging your expertise in healthcare to drive exceptional patient outcomes, foster community relationships, and cultivate a positive team culture in a dynamic clinic environm...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Champion customer success by driving impactful relationships, ensuring clients maximize platform value through effective training and insights. Collaborate cross-functionally to enhance account growth...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $100K *

Drive daily operations in a dynamic emergency department, overseeing nursing staff and ensuring high-quality patient care. Collaborate with multidisciplinary teams to enhance service delivery and impl...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $120K *

Shape the future of marketing strategy for a premier industry expo, driving attendance and engagement through innovative campaigns and cross-functional collaboration. Lead a dynamic team to enhance br...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$175K - $200K *

Transform compliance within a dynamic enterprise by designing and overseeing an effective Ethics and Compliance Program that aligns with regulations and promotes enterprise growth. Drive culture and a...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Support patient evaluations by conducting psychological assessments and collaborating with a clinical team to enhance diagnostic outcomes and treatment plans. Leverage expertise in standardized testin...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K *

Lead the charge in enhancing patient care by overseeing clinical operations, guiding staff, and ensuring compliance with regulations. Collaborate with the Executive Director to maintain high-quality h...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Tackle the challenge of bridging IT and business units, ensuring alignment with healthcare priorities. Collaborate with stakeholders to gather requirements, document processes, and foster a culture of...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Engage with mission-driven organizations to drive growth in housing solutions. Own the full sales lifecycle, from prospecting to closing, while expanding your portfolio and collaborating across teams...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Lead the clinical services at a premier behavioral health facility, driving strategic planning and program development to enhance community care and meet performance goals in a supportive environment...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Contribute to the development of scalable data solutions that enhance analytics and product functionality, collaborating with cross-functional teams to drive improvements in data infrastructure and su...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$111K *

Unlock potential by leading Clinical Documentation Integrity operations, enhancing physician engagement, and driving performance improvement. Collaborate with diverse teams to ensure compliance and op...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$230K - $260K *

Join a dedicated team of Psychiatric Nurse Practitioners focused on delivering high-quality behavioral healthcare. Enjoy flexible schedules, a supportive environment, and opportunities for professiona...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Explore opportunities as a Senior Security Engineer, safeguarding the DeFi ecosystem by identifying vulnerabilities, enhancing monitoring tools, and ensuring compliance with security protocols. Collab...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$72K - $90K *

Champion safety and compliance by leading EHS programs, conducting audits, and delivering training. Collaborate with teams to enhance workplace safety and ensure adherence to regulations while driving...

2 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $115K *

Unlock potential by providing vital sales support and presentations, driving customer integration and product utilization, while conducting market research to enhance offerings. Collaborate closely wi...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Join us to architect a unified web platform that enhances user experience across multiple services. Lead front-end development, optimize performance, and mentor engineers while ensuring seamless integ...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$133K - $147K *

Help us guide financial institutions to measurable outcomes through expert value consulting. Leverage your analytical skills and industry knowledge to influence engagement, optimize platform usage, an...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Manage implementation projects, ensuring clear ownership and accountability across complex customer engagements while maintaining rigorous oversight of critical paths and deliverables for timely launc...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$75K - $90K *

Take ownership of national account strategies, driving sales growth and fostering relationships with key retail partners. Lead product initiatives and collaborate with cross-functional teams to enhanc...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.