Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$80K - $95K *

Join a team that's dedicated to enhancing client experiences through exceptional facility management. Oversee multiple locations, collaborate on strategic initiatives, and ensure a welcoming atmospher...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$150K - $200K *

Unlock potential by defining and guiding enterprise architecture, integrating cloud, infrastructure, and security to support business priorities. Lead modernization efforts and influence cross-functio...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Innovate within a dynamic team, driving impactful projects and solutions that enhance operational efficiency and foster growth across multiple departments. Your expertise will shape strategic initiati...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Partner with us to enhance veterinary medical support through education, training, and product expertise. Engage with veterinarians and sales teams to ensure compliance and promote American Regent Ani...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join our team to drive sales across a defined portfolio, engaging healthcare organizations with our innovative solutions. Own the sales cycle from prospecting to closing while collaborating with inter...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $192K *

Manage territory business plans to drive sales performance, engage healthcare providers, and support product launches. Collaborate with cross-functional teams to optimize patient access and ensure com...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Unlock product potential by leading the development of innovative food safety solutions. Collaborate with cross-functional teams to address complex industry challenges and drive scalable product strat...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Lead the charge in enhancing patient and workplace safety through strategic risk management initiatives. Collaborate across departments to identify risks, ensure compliance, and foster a culture of sa...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$91K - $179K *

Drive operational excellence in manufacturing through digital transformation solutions, working with cross-functional teams to enhance efficiency, quality, and visibility across production processes w...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$91K - $179K *

Join a team that's transforming manufacturing through digital solutions. Drive operational efficiency and enhance production processes while collaborating with cross-functional teams to build robust s...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$180K - $220K *

Drive clinical excellence by providing medical expertise across therapeutic areas, ensuring safety and integrity in clinical trials. Collaborate with project teams and senior management to enhance cli...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion advanced analytics initiatives to enhance supply chain efficiency, drive strategic decision-making, and improve mission readiness through actionable insights and predictive modeling across di...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Explore forensic pathology by conducting postmortem examinations, determining causes of death, and collaborating with law enforcement and legal entities. Engage in community education and mentorship w...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$62K - $112K *

Transform member engagement by proactively addressing concerns, coordinating solutions, and enhancing satisfaction. Collaborate with cross-functional teams to drive improvements and ensure a seamless...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Transportation

$125K - $150K *

Join a dynamic team to advance pediatric hematology through clinical care, teaching, and innovative research. Engage with students and fellows while contributing to impactful scholarship in a collabor...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $96K *

Innovate clinical services for adults in a Residential Treatment Facility by conducting assessments, developing treatment plans, and collaborating with a multidisciplinary team to enhance client growt...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$228K - $342K *

Drive technical strategies and influence enterprise executives to enhance identity security. Mentor teams, shape product direction, and engage with Fortune 500 leaders to tackle complex security chall...

RemoteRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$120K - $150K *

Elevate your career as a leader in veterinary medicine, overseeing medical quality and patient care while driving strategic direction. Balance clinical duties with leadership responsibilities in a sup...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Transform healthcare by leading a dynamic team in clinical pharmacy services, ensuring safe and effective medication management while optimizing patient care and operational efficiency...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$275K - $335K *

Launch innovative marketing strategies to create a new category in veterinary medicine. Collaborate with teams to build brand credibility and consumer awareness for a groundbreaking longevity drug for...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $100K *

Shape the future of behavioral healthcare by delivering exceptional patient care. Collaborate with a dedicated team in a supportive environment, focusing on professional growth and work-life balance w...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Champion patient care by providing outpatient psychiatric services to adults. Collaborate with a multidisciplinary team to deliver evaluations and medication management, ensuring comprehensive support...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $104K *

Unlock your potential as a Speech Language Pathologist, delivering tailored rehab services to enhance communication and swallowing abilities. Collaborate with patients and peers to create impactful tr...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $104K *

Advance patient communication and swallowing abilities by designing and implementing tailored rehabilitation plans. Collaborate with peers and educate patients and caregivers to foster independence an...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $104K *

Join us to empower patients by enhancing their communication and swallowing abilities. As a Speech Language Pathologist, you'll design and implement personalized rehab plans, collaborating with peers...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.