Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$110K - $130K *

Elevate client relationships by leading Client Success teams to ensure operational excellence, proactive issue resolution, and strategic growth, while fostering collaboration across departments to enh...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $225K *

Drive innovative design solutions as a Staff Product Designer, leading strategy and experience design for a new judiciary product. Collaborate with cross-functional teams to create impactful user expe...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $170K *

Lead the charge in managing strategic partnerships, leveraging data insights to drive growth and retention. Collaborate cross-functionally to enhance partner performance and operational excellence whi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Shape the future of patient care by providing expert pharmaceutical services, ensuring safe medication use, and collaborating with healthcare teams to enhance patient outcomes through effective drug t...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $192K *

Empower your career by driving commercial success as you engage healthcare providers, build relationships, and support innovative therapies in a dynamic, remote role focused on impactful patient outco...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $120K *

Help us drive sales growth and enhance community partnerships by leading a dynamic sales team focused on expanding market share and improving patient registrations in the healthcare sector...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Lead the charge in delivering high-quality surgical care by providing comprehensive inpatient and perioperative services. Collaborate with multidisciplinary teams to enhance patient outcomes and advoc...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of secure software development by integrating security practices into engineering workflows, building automation tools, and conducting penetration tests to identify vulnerabilities an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $166K *

Lead the charge in managing site contract negotiations and agreements, ensuring alignment with clinical study timelines. Collaborate with cross-functional teams to enhance contract processes and mento...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$122K - $171K *

Unlock potential by driving data-driven insights for Customer Success. Collaborate across teams to enhance customer journeys, optimize growth strategies, and shape analytics foundations that support A...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Lead the charge in delivering exceptional pharmaceutical care, overseeing clinical and production pharmacy services, ensuring patient safety, and collaborating with healthcare teams to optimize medica...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Lead cross-functional teams to enhance the Epic Resolute Hospital Billing application, ensuring project milestones are met while driving process improvements and delivering exceptional service to inte...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate imaging services by leading a dynamic team, ensuring quality care and operational excellence across multiple outpatient facilities while fostering a collaborative environment...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive client success by managing relationships, optimizing collections, and resolving issues. Collaborate with diverse stakeholders to ensure satisfaction and compliance while leading a team to enhanc...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Empower patients by conducting comprehensive eye exams and fostering long-term relationships. Collaborate with staff to provide exceptional care, diagnose conditions, and recommend treatments, all whi...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Champion eye health by conducting comprehensive exams, diagnosing issues, and fostering long-term patient relationships through education and optimal care solutions while maximizing the practice's gro...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $130K *

Empower your veterinary career by delivering exceptional care in a supportive environment. Join a dedicated team focused on meaningful relationships and clinical independence, while enjoying a variety...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Empower pet health through quality veterinary care, bolstered by mentorship and a collaborative culture. Join a devoted team committed to clinical excellence while enjoying work-life balance and profe...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Engage your career with a dynamic team dedicated to delivering high-quality behavioral healthcare. Enjoy flexible schedules, competitive compensation, and a supportive environment focused on professio...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Lead end-to-end healthcare AI deployments, ensuring alignment with clinical workflows and driving measurable impact through strategic partnerships and hands-on execution in complex environments...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Unlock potential by becoming a key business advisor, delivering tailored audit and assurance services to middle market clients. Collaborate with leadership to drive growth, mentor talent, and enhance...

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Serve as a key business advisor, delivering industry-focused audit services while mentoring staff and driving growth. Collaborate with leadership to enhance client relationships and ensure quality ser...

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$125K - $150K *

Join a team that's redefining audit services, providing expert guidance and mentorship while delivering tailored assurance solutions to enhance client success in specific industries. Shape your career...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$90K - $110K *

Reimagine workplace health as you provide comprehensive care to employees, conducting exams, developing care plans, and collaborating with healthcare teams. Enjoy a consistent schedule with no nights...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$88K *

Empower patient wellness by delivering hands-on care in a supportive clinic. Build lasting relationships while performing assessments, treatments, and education to enhance men's health outcomes in a c...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.