Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$80K - $95K *

Accelerate your nursing career by leading care delivery in our Cardiac Cath Lab, fostering team growth, mentoring staff, and enhancing patient experiences through collaboration and evidence-based prac...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $140K *

Empower provider accounts post-launch by driving growth through strategic engagement, tailored training, and effective collaboration with internal teams. Cultivate relationships across diverse healthc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Unlock potential by shaping mobile development solutions and guiding implementation teams to deliver projects following your architectural designs, ensuring quality and effectiveness throughout the de...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Lead compliance initiatives across multiple states, ensuring adherence to healthcare regulations. Collaborate with operations to localize policies, deliver training, and monitor regulatory changes, dr...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Lead mobile solution design and architecture, translating business needs into robust software blueprints. Ensure design adherence, guide implementation teams, and uphold project integrity while collab...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Information Technology

$88K - $105K *

Lead the charge in organizing and overseeing clinical laboratory operations, ensuring compliance with standards and regulations while enhancing service quality and team performance across all laborato...

Today

  •   5 - 7 years exp.  •   Healthcare

$85K - $95K *

Lead the charge in client engagement and lifecycle management, driving retention and organic growth within legal accounts. Build relationships, identify cross-sell opportunities, and ensure high clien...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$58K - $110K *

Take ownership of third-party risk management by assessing vendors, documenting risks, and ensuring compliance. Collaborate with cross-functional teams to enhance security measures and support audits...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$87K - $151K *

Unlock potential by providing expert remote clinical applications support for advanced molecular imaging. Leverage your clinical knowledge and customer service skills to enhance productivity and deliv...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Transform healthcare delivery by leading nursing services, ensuring high-quality patient care, compliance with regulations, and fostering staff development in a dynamic environment. Drive operational...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$242K - $303K *

Join as the primary privacy leader to manage and enhance an enterprise-wide privacy program while navigating complex regulations. Collaborate across departments to drive compliance, innovation, and ef...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Join a visionary team to lead operational excellence in clinical education, driving performance and innovation within a dynamic network. Shape the future of graduate medical education while prioritizi...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Lead the charge in enhancing patient outcomes through effective Care Management processes, ensuring compliance with regulatory standards while providing clinical and administrative direction to staff...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Oversee the Care Management process, ensuring regulatory compliance and optimal patient outcomes. Lead clinical and administrative teams, provide training, and monitor performance metrics to enhance c...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $162K *

Champion customer support by managing maintenance services and operations. Lead a team to ensure timely resolutions and enhance product performance while utilizing technical expertise and strategic pl...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Elevate client relationships by leading Client Success teams to ensure operational excellence, proactive issue resolution, and strategic growth, while fostering collaboration across departments to enh...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $225K *

Drive innovative design solutions as a Staff Product Designer, leading strategy and experience design for a new judiciary product. Collaborate with cross-functional teams to create impactful user expe...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $170K *

Lead the charge in managing strategic partnerships, leveraging data insights to drive growth and retention. Collaborate cross-functionally to enhance partner performance and operational excellence whi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Shape the future of patient care by providing expert pharmaceutical services, ensuring safe medication use, and collaborating with healthcare teams to enhance patient outcomes through effective drug t...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $192K *

Empower your career by driving commercial success as you engage healthcare providers, build relationships, and support innovative therapies in a dynamic, remote role focused on impactful patient outco...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $120K *

Help us drive sales growth and enhance community partnerships by leading a dynamic sales team focused on expanding market share and improving patient registrations in the healthcare sector...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Lead the charge in delivering high-quality surgical care by providing comprehensive inpatient and perioperative services. Collaborate with multidisciplinary teams to enhance patient outcomes and advoc...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of secure software development by integrating security practices into engineering workflows, building automation tools, and conducting penetration tests to identify vulnerabilities an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $166K *

Lead the charge in managing site contract negotiations and agreements, ensuring alignment with clinical study timelines. Collaborate with cross-functional teams to enhance contract processes and mento...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$122K - $171K *

Unlock potential by driving data-driven insights for Customer Success. Collaborate across teams to enhance customer journeys, optimize growth strategies, and shape analytics foundations that support A...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.